| Full name: ABI family member 3 | Alias Symbol: NESH|SSH3BP3 | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 51225 | HGNC ID: HGNC:29859 | Ensembl Gene: ENSG00000108798 | OMIM ID: 606363 |
| Drug and gene relationship at DGIdb | |||
Expression of ABI3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABI3 | 51225 | 223615_at | 0.1805 | 0.6626 | |
| GSE26886 | ABI3 | 51225 | 223615_at | -0.1001 | 0.5180 | |
| GSE45670 | ABI3 | 51225 | 223615_at | 0.1221 | 0.1744 | |
| GSE53622 | ABI3 | 51225 | 25427 | 0.0683 | 0.4553 | |
| GSE53624 | ABI3 | 51225 | 25427 | 0.0493 | 0.5762 | |
| GSE63941 | ABI3 | 51225 | 223615_at | 0.1926 | 0.1353 | |
| GSE77861 | ABI3 | 51225 | 223615_at | -0.1149 | 0.2493 | |
| GSE97050 | ABI3 | 51225 | A_23_P141429 | 0.3633 | 0.2864 | |
| SRP007169 | ABI3 | 51225 | RNAseq | 0.3502 | 0.6792 | |
| SRP064894 | ABI3 | 51225 | RNAseq | 0.6502 | 0.0359 | |
| SRP133303 | ABI3 | 51225 | RNAseq | -0.0485 | 0.8457 | |
| SRP159526 | ABI3 | 51225 | RNAseq | -0.4271 | 0.4879 | |
| SRP193095 | ABI3 | 51225 | RNAseq | -0.1756 | 0.3085 | |
| SRP219564 | ABI3 | 51225 | RNAseq | 0.3446 | 0.3758 | |
| TCGA | ABI3 | 51225 | RNAseq | 0.1176 | 0.3571 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABI3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABI3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABI3 | 51225 | 6 | 2 | 22 | |
| GSE20123 | ABI3 | 51225 | 6 | 2 | 22 | |
| GSE43470 | ABI3 | 51225 | 3 | 2 | 38 | |
| GSE46452 | ABI3 | 51225 | 32 | 0 | 27 | |
| GSE47630 | ABI3 | 51225 | 9 | 0 | 31 | |
| GSE54993 | ABI3 | 51225 | 2 | 4 | 64 | |
| GSE54994 | ABI3 | 51225 | 10 | 6 | 37 | |
| GSE60625 | ABI3 | 51225 | 4 | 0 | 7 | |
| GSE74703 | ABI3 | 51225 | 3 | 2 | 31 | |
| GSE74704 | ABI3 | 51225 | 4 | 1 | 15 | |
| TCGA | ABI3 | 51225 | 27 | 7 | 62 |
Total number of gains: 106; Total number of losses: 26; Total Number of normals: 356.
Somatic mutations of ABI3:
Generating mutation plots.
Highly correlated genes for ABI3:
Showing top 20/374 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABI3 | SEZ6L2 | 0.758017 | 3 | 0 | 3 |
| ABI3 | CD52 | 0.713976 | 6 | 0 | 6 |
| ABI3 | IL10RA | 0.709781 | 5 | 0 | 5 |
| ABI3 | IL21R | 0.705912 | 6 | 0 | 5 |
| ABI3 | ALPL | 0.693373 | 3 | 0 | 3 |
| ABI3 | GABRD | 0.687776 | 3 | 0 | 3 |
| ABI3 | BMF | 0.6876 | 3 | 0 | 3 |
| ABI3 | EVI2A | 0.687447 | 3 | 0 | 3 |
| ABI3 | DDC | 0.685293 | 4 | 0 | 4 |
| ABI3 | TBC1D10C | 0.684035 | 7 | 0 | 6 |
| ABI3 | LST1 | 0.683823 | 5 | 0 | 4 |
| ABI3 | MIIP | 0.683766 | 3 | 0 | 3 |
| ABI3 | FAM78A | 0.683207 | 5 | 0 | 4 |
| ABI3 | MZB1 | 0.683178 | 4 | 0 | 3 |
| ABI3 | CD48 | 0.680367 | 7 | 0 | 6 |
| ABI3 | FEV | 0.677458 | 3 | 0 | 3 |
| ABI3 | GPR26 | 0.676802 | 3 | 0 | 3 |
| ABI3 | GPR35 | 0.673801 | 4 | 0 | 3 |
| ABI3 | TRAT1 | 0.673058 | 4 | 0 | 3 |
| ABI3 | CDH4 | 0.671918 | 3 | 0 | 3 |
For details and further investigation, click here
