| Full name: surfactant associated 3 | Alias Symbol: NANCI | ||
| Type: protein-coding gene | Cytoband: 14q13.3 | ||
| Entrez ID: 253970 | HGNC ID: HGNC:18387 | Ensembl Gene: ENSG00000229415 | OMIM ID: 617860 |
| Drug and gene relationship at DGIdb | |||
Expression of SFTA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFTA3 | 253970 | 228979_at | -0.0013 | 0.9969 | |
| GSE26886 | SFTA3 | 253970 | 228979_at | 0.0638 | 0.3890 | |
| GSE45670 | SFTA3 | 253970 | 228979_at | 0.0335 | 0.6287 | |
| GSE53622 | SFTA3 | 253970 | 38427 | 0.2924 | 0.0000 | |
| GSE53624 | SFTA3 | 253970 | 38427 | 0.5260 | 0.0000 | |
| GSE63941 | SFTA3 | 253970 | 228979_at | 0.4062 | 0.6056 | |
| GSE77861 | SFTA3 | 253970 | 228979_at | 0.0510 | 0.5367 | |
| TCGA | SFTA3 | 253970 | RNAseq | 1.6984 | 0.4194 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SFTA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFTA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFTA3 | 253970 | 11 | 4 | 15 | |
| GSE20123 | SFTA3 | 253970 | 12 | 4 | 14 | |
| GSE43470 | SFTA3 | 253970 | 8 | 2 | 33 | |
| GSE46452 | SFTA3 | 253970 | 18 | 2 | 39 | |
| GSE47630 | SFTA3 | 253970 | 11 | 10 | 19 | |
| GSE54993 | SFTA3 | 253970 | 3 | 11 | 56 | |
| GSE54994 | SFTA3 | 253970 | 19 | 5 | 29 | |
| GSE60625 | SFTA3 | 253970 | 0 | 2 | 9 | |
| GSE74703 | SFTA3 | 253970 | 7 | 2 | 27 | |
| GSE74704 | SFTA3 | 253970 | 6 | 3 | 11 | |
| TCGA | SFTA3 | 253970 | 35 | 14 | 47 |
Total number of gains: 130; Total number of losses: 59; Total Number of normals: 299.
Somatic mutations of SFTA3:
Generating mutation plots.
Highly correlated genes for SFTA3:
Showing top 20/26 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFTA3 | PPP5C | 0.686888 | 3 | 0 | 3 |
| SFTA3 | SHISA7 | 0.683491 | 3 | 0 | 3 |
| SFTA3 | LGALS12 | 0.664579 | 3 | 0 | 3 |
| SFTA3 | STAC3 | 0.650767 | 3 | 0 | 3 |
| SFTA3 | PANX2 | 0.632289 | 3 | 0 | 3 |
| SFTA3 | LAT2 | 0.629211 | 3 | 0 | 3 |
| SFTA3 | WDR64 | 0.628132 | 3 | 0 | 3 |
| SFTA3 | ODF3L2 | 0.620985 | 3 | 0 | 3 |
| SFTA3 | TOR2A | 0.607881 | 3 | 0 | 3 |
| SFTA3 | CNOT3 | 0.600667 | 4 | 0 | 3 |
| SFTA3 | STMN4 | 0.587885 | 4 | 0 | 3 |
| SFTA3 | CABP4 | 0.583952 | 4 | 0 | 3 |
| SFTA3 | LINC00858 | 0.581902 | 4 | 0 | 3 |
| SFTA3 | MYBPC3 | 0.569958 | 4 | 0 | 3 |
| SFTA3 | ELFN1 | 0.557766 | 5 | 0 | 3 |
| SFTA3 | IL1F10 | 0.556991 | 4 | 0 | 3 |
| SFTA3 | INSC | 0.556414 | 3 | 0 | 3 |
| SFTA3 | ADAM8 | 0.551601 | 5 | 0 | 3 |
| SFTA3 | GRAMD1B | 0.540186 | 3 | 0 | 3 |
| SFTA3 | APOA2 | 0.53491 | 4 | 0 | 3 |
For details and further investigation, click here
