| Full name: zinc finger protein 3 | Alias Symbol: A8-51|KOX25|PP838|FLJ20216|HF.12|Zfp113 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 7551 | HGNC ID: HGNC:13089 | Ensembl Gene: ENSG00000166526 | OMIM ID: 194510 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF3 | 7551 | 212684_at | 0.4641 | 0.3817 | |
| GSE20347 | ZNF3 | 7551 | 212684_at | 0.7705 | 0.0001 | |
| GSE23400 | ZNF3 | 7551 | 219605_at | -0.1168 | 0.0008 | |
| GSE26886 | ZNF3 | 7551 | 212684_at | 0.2146 | 0.5424 | |
| GSE29001 | ZNF3 | 7551 | 212684_at | 0.2650 | 0.5715 | |
| GSE38129 | ZNF3 | 7551 | 212684_at | 0.7731 | 0.0000 | |
| GSE45670 | ZNF3 | 7551 | 212684_at | 0.3815 | 0.0581 | |
| GSE53622 | ZNF3 | 7551 | 30112 | 0.5218 | 0.0000 | |
| GSE53624 | ZNF3 | 7551 | 30112 | 0.4568 | 0.0000 | |
| GSE63941 | ZNF3 | 7551 | 212684_at | -1.1557 | 0.0242 | |
| GSE77861 | ZNF3 | 7551 | 212684_at | 0.3481 | 0.0656 | |
| GSE97050 | ZNF3 | 7551 | A_23_P219084 | 0.1351 | 0.7210 | |
| SRP007169 | ZNF3 | 7551 | RNAseq | 0.3852 | 0.3266 | |
| SRP008496 | ZNF3 | 7551 | RNAseq | 1.0382 | 0.0085 | |
| SRP064894 | ZNF3 | 7551 | RNAseq | 0.1642 | 0.1531 | |
| SRP133303 | ZNF3 | 7551 | RNAseq | 0.4357 | 0.0157 | |
| SRP159526 | ZNF3 | 7551 | RNAseq | 0.5991 | 0.0108 | |
| SRP193095 | ZNF3 | 7551 | RNAseq | 0.4309 | 0.0036 | |
| SRP219564 | ZNF3 | 7551 | RNAseq | 0.5566 | 0.1456 | |
| TCGA | ZNF3 | 7551 | RNAseq | 0.0030 | 0.9588 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ZNF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF3 | 7551 | 13 | 0 | 17 | |
| GSE20123 | ZNF3 | 7551 | 13 | 0 | 17 | |
| GSE43470 | ZNF3 | 7551 | 6 | 2 | 35 | |
| GSE46452 | ZNF3 | 7551 | 11 | 1 | 47 | |
| GSE47630 | ZNF3 | 7551 | 7 | 3 | 30 | |
| GSE54993 | ZNF3 | 7551 | 1 | 9 | 60 | |
| GSE54994 | ZNF3 | 7551 | 16 | 3 | 34 | |
| GSE60625 | ZNF3 | 7551 | 0 | 0 | 11 | |
| GSE74703 | ZNF3 | 7551 | 6 | 1 | 29 | |
| GSE74704 | ZNF3 | 7551 | 9 | 0 | 11 | |
| TCGA | ZNF3 | 7551 | 52 | 6 | 38 |
Total number of gains: 134; Total number of losses: 25; Total Number of normals: 329.
Somatic mutations of ZNF3:
Generating mutation plots.
Highly correlated genes for ZNF3:
Showing top 20/675 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF3 | PROSER1 | 0.873366 | 3 | 0 | 3 |
| ZNF3 | SENP1 | 0.798721 | 3 | 0 | 3 |
| ZNF3 | PIP4K2C | 0.788748 | 3 | 0 | 3 |
| ZNF3 | STX10 | 0.766058 | 3 | 0 | 3 |
| ZNF3 | EXOC6 | 0.757537 | 4 | 0 | 4 |
| ZNF3 | GCLC | 0.754549 | 3 | 0 | 3 |
| ZNF3 | ZNF740 | 0.742929 | 3 | 0 | 3 |
| ZNF3 | SHPRH | 0.739428 | 3 | 0 | 3 |
| ZNF3 | TFIP11 | 0.736532 | 3 | 0 | 3 |
| ZNF3 | SMARCAD1 | 0.732614 | 3 | 0 | 3 |
| ZNF3 | ZNF324 | 0.729482 | 3 | 0 | 3 |
| ZNF3 | MED14 | 0.725757 | 3 | 0 | 3 |
| ZNF3 | DLG5 | 0.724713 | 3 | 0 | 3 |
| ZNF3 | RNF113A | 0.718872 | 3 | 0 | 3 |
| ZNF3 | SLC25A28 | 0.717171 | 3 | 0 | 3 |
| ZNF3 | USE1 | 0.714358 | 4 | 0 | 3 |
| ZNF3 | EPS8 | 0.71353 | 4 | 0 | 3 |
| ZNF3 | SLC35A2 | 0.708801 | 4 | 0 | 4 |
| ZNF3 | BCL7C | 0.70843 | 3 | 0 | 3 |
| ZNF3 | TRPM4 | 0.708065 | 3 | 0 | 3 |
For details and further investigation, click here
