| Full name: SHQ1, H/ACA ribonucleoprotein assembly factor | Alias Symbol: FLJ10539|Shq1p | ||
| Type: protein-coding gene | Cytoband: 3p13 | ||
| Entrez ID: 55164 | HGNC ID: HGNC:25543 | Ensembl Gene: ENSG00000144736 | OMIM ID: 613663 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SHQ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHQ1 | 55164 | 219083_at | 0.2737 | 0.4781 | |
| GSE20347 | SHQ1 | 55164 | 219083_at | -0.1786 | 0.3806 | |
| GSE23400 | SHQ1 | 55164 | 219083_at | 0.1512 | 0.0148 | |
| GSE26886 | SHQ1 | 55164 | 219083_at | -0.7668 | 0.0000 | |
| GSE29001 | SHQ1 | 55164 | 219083_at | 0.1750 | 0.5528 | |
| GSE38129 | SHQ1 | 55164 | 219083_at | -0.0273 | 0.8548 | |
| GSE45670 | SHQ1 | 55164 | 219083_at | 0.1147 | 0.2182 | |
| GSE53622 | SHQ1 | 55164 | 77257 | 0.1665 | 0.0848 | |
| GSE53624 | SHQ1 | 55164 | 77257 | 0.0490 | 0.6576 | |
| GSE63941 | SHQ1 | 55164 | 219083_at | -0.4871 | 0.2079 | |
| GSE77861 | SHQ1 | 55164 | 219083_at | -0.2262 | 0.3323 | |
| GSE97050 | SHQ1 | 55164 | A_33_P3236133 | 0.2117 | 0.2802 | |
| SRP007169 | SHQ1 | 55164 | RNAseq | -0.3702 | 0.4463 | |
| SRP008496 | SHQ1 | 55164 | RNAseq | 0.1718 | 0.6206 | |
| SRP064894 | SHQ1 | 55164 | RNAseq | 0.0069 | 0.9666 | |
| SRP133303 | SHQ1 | 55164 | RNAseq | -0.0186 | 0.8654 | |
| SRP159526 | SHQ1 | 55164 | RNAseq | -0.1287 | 0.6936 | |
| SRP193095 | SHQ1 | 55164 | RNAseq | -0.2486 | 0.0094 | |
| SRP219564 | SHQ1 | 55164 | RNAseq | -0.2842 | 0.2331 | |
| TCGA | SHQ1 | 55164 | RNAseq | -0.0299 | 0.6051 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SHQ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SHQ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHQ1 | 55164 | 1 | 20 | 9 | |
| GSE20123 | SHQ1 | 55164 | 1 | 20 | 9 | |
| GSE43470 | SHQ1 | 55164 | 0 | 21 | 22 | |
| GSE46452 | SHQ1 | 55164 | 2 | 17 | 40 | |
| GSE47630 | SHQ1 | 55164 | 1 | 23 | 16 | |
| GSE54993 | SHQ1 | 55164 | 4 | 3 | 63 | |
| GSE54994 | SHQ1 | 55164 | 1 | 31 | 21 | |
| GSE60625 | SHQ1 | 55164 | 3 | 1 | 7 | |
| GSE74703 | SHQ1 | 55164 | 0 | 17 | 19 | |
| GSE74704 | SHQ1 | 55164 | 1 | 13 | 6 | |
| TCGA | SHQ1 | 55164 | 1 | 79 | 16 |
Total number of gains: 15; Total number of losses: 245; Total Number of normals: 228.
Somatic mutations of SHQ1:
Generating mutation plots.
Highly correlated genes for SHQ1:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHQ1 | MAP3K9 | 0.820291 | 3 | 0 | 3 |
| SHQ1 | HECTD1 | 0.754923 | 3 | 0 | 3 |
| SHQ1 | EBP | 0.736102 | 3 | 0 | 3 |
| SHQ1 | SLC35C1 | 0.735223 | 3 | 0 | 3 |
| SHQ1 | ZNF780A | 0.716734 | 3 | 0 | 3 |
| SHQ1 | TCAIM | 0.715183 | 3 | 0 | 3 |
| SHQ1 | RTKN2 | 0.683982 | 3 | 0 | 3 |
| SHQ1 | GEMIN2 | 0.676998 | 4 | 0 | 3 |
| SHQ1 | SEMA5A | 0.668446 | 4 | 0 | 3 |
| SHQ1 | SDR42E1 | 0.660624 | 3 | 0 | 3 |
| SHQ1 | WDR44 | 0.658502 | 3 | 0 | 3 |
| SHQ1 | MYLK4 | 0.644905 | 4 | 0 | 4 |
| SHQ1 | ZDHHC20 | 0.644234 | 4 | 0 | 4 |
| SHQ1 | ERMP1 | 0.642123 | 4 | 0 | 3 |
| SHQ1 | TUSC2 | 0.633517 | 4 | 0 | 3 |
| SHQ1 | PSMD6 | 0.62663 | 6 | 0 | 5 |
| SHQ1 | INO80C | 0.625687 | 3 | 0 | 3 |
| SHQ1 | MAPKAPK3 | 0.624495 | 5 | 0 | 3 |
| SHQ1 | KLK13 | 0.621106 | 3 | 0 | 3 |
| SHQ1 | KCTD5 | 0.619175 | 6 | 0 | 5 |
For details and further investigation, click here
