GEMIN2

 

Full name: gem nuclear organelle associated protein 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 14q21.1
Entrez ID: 8487 HGNC ID: HGNC:10884 Ensembl Gene: ENSG00000092208 OMIM ID: 602595

 

Expression of GEMIN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GEMIN2 8487 211115_x_at 1.0480 0.2131
GSE20347 GEMIN2 8487 211115_x_at 1.2420 0.0001
GSE23400 GEMIN2 8487 211115_x_at 0.2838 0.0000
GSE26886 GEMIN2 8487 211115_x_at -0.9847 0.0003
GSE29001 GEMIN2 8487 211115_x_at 0.3966 0.1030
GSE38129 GEMIN2 8487 211115_x_at 1.1500 0.0000
GSE45670 GEMIN2 8487 211115_x_at 0.7183 0.0004
GSE53622 GEMIN2 8487 112775 0.4335 0.0015
GSE53624 GEMIN2 8487 29593 0.9534 0.0000
GSE63941 GEMIN2 8487 211115_x_at 1.9906 0.0019
GSE77861 GEMIN2 8487 211115_x_at 0.0929 0.7781
GSE97050 GEMIN2 A_21_P0012376 0.3778 0.2785
SRP007169 GEMIN2 8487 RNAseq 1.3753 0.0107
SRP008496 GEMIN2 8487 RNAseq 1.5205 0.0001
SRP064894 GEMIN2 8487 RNAseq 1.1478 0.0000
SRP133303 GEMIN2 8487 RNAseq 1.5139 0.0000
SRP159526 GEMIN2 8487 RNAseq 1.1135 0.0385
SRP193095 GEMIN2 8487 RNAseq 0.7195 0.0000
SRP219564 GEMIN2 8487 RNAseq 0.9000 0.0163

Upregulated datasets: 8; Downregulated datasets: 0.  


 

Survival by GEMIN2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of GEMIN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GEMIN2 8487 9 5 16
GSE20123 GEMIN2 8487 9 5 16
GSE43470 GEMIN2 8487 9 3 31
GSE46452 GEMIN2 8487 18 2 39
GSE47630 GEMIN2 8487 11 10 19
GSE54993 GEMIN2 8487 3 9 58
GSE54994 GEMIN2 8487 19 5 29
GSE60625 GEMIN2 8487 0 2 9
GSE74703 GEMIN2 8487 8 3 25
GSE74704 GEMIN2 8487 4 3 13
TCGA GEMIN2 8487 35 13 48

Total number of gains: 125; Total number of losses: 60; Total Number of normals: 303.  


 

Somatic mutations of GEMIN2:

 

Generating mutation plots.

 

Highly correlated genes for GEMIN2:

 

Showing top 20/203 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GEMIN2SCLY0.76941303
GEMIN2ARHGAP220.752748303
GEMIN2LRR10.71949706
GEMIN2PCP20.7122303
GEMIN2COPS7B0.696656404
GEMIN2NUP980.69623403
GEMIN2ZNF1140.695948303
GEMIN2RCC20.6919404
GEMIN2CDCA50.686108605
GEMIN2C4orf460.677185303
GEMIN2SHQ10.676998403
GEMIN2POLE20.6714451109
GEMIN2RAG20.670152303
GEMIN2POC1A0.666583604
GEMIN2ERI10.665697403
GEMIN2AURKB0.65933808
GEMIN2OIP50.659197808
GEMIN2STRIP20.658348303
GEMIN2PSMA30.6542881008
GEMIN2RFT10.65123503

For details and further investigation, click here