| Full name: proteasome 26S subunit, non-ATPase 6 | Alias Symbol: S10|p44S10|KIAA0107|Rpn7 | ||
| Type: protein-coding gene | Cytoband: 3p14.1 | ||
| Entrez ID: 9861 | HGNC ID: HGNC:9564 | Ensembl Gene: ENSG00000163636 | OMIM ID: 617857 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMD6 | 9861 | 202753_at | -0.1681 | 0.4969 | |
| GSE20347 | PSMD6 | 9861 | 202753_at | -0.5184 | 0.0017 | |
| GSE23400 | PSMD6 | 9861 | 202753_at | -0.1878 | 0.0018 | |
| GSE26886 | PSMD6 | 9861 | 202753_at | -1.0509 | 0.0000 | |
| GSE29001 | PSMD6 | 9861 | 202753_at | -0.2548 | 0.3024 | |
| GSE38129 | PSMD6 | 9861 | 202753_at | -0.2952 | 0.0130 | |
| GSE45670 | PSMD6 | 9861 | 202753_at | -0.1469 | 0.1931 | |
| GSE53622 | PSMD6 | 9861 | 35114 | 0.0596 | 0.7761 | |
| GSE53624 | PSMD6 | 9861 | 35114 | -0.3341 | 0.0065 | |
| GSE63941 | PSMD6 | 9861 | 202753_at | -0.1076 | 0.7677 | |
| GSE77861 | PSMD6 | 9861 | 202753_at | -0.4163 | 0.2330 | |
| GSE97050 | PSMD6 | 9861 | A_23_P109928 | 0.0597 | 0.9500 | |
| SRP007169 | PSMD6 | 9861 | RNAseq | -1.0581 | 0.0008 | |
| SRP008496 | PSMD6 | 9861 | RNAseq | -0.9040 | 0.0000 | |
| SRP064894 | PSMD6 | 9861 | RNAseq | -0.4977 | 0.0000 | |
| SRP133303 | PSMD6 | 9861 | RNAseq | -0.2095 | 0.0714 | |
| SRP159526 | PSMD6 | 9861 | RNAseq | -0.4806 | 0.0384 | |
| SRP193095 | PSMD6 | 9861 | RNAseq | -0.6734 | 0.0000 | |
| SRP219564 | PSMD6 | 9861 | RNAseq | -0.7224 | 0.0000 | |
| TCGA | PSMD6 | 9861 | RNAseq | -0.0196 | 0.6904 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PSMD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMD6 | 9861 | 0 | 18 | 12 | |
| GSE20123 | PSMD6 | 9861 | 0 | 18 | 12 | |
| GSE43470 | PSMD6 | 9861 | 0 | 19 | 24 | |
| GSE46452 | PSMD6 | 9861 | 2 | 17 | 40 | |
| GSE47630 | PSMD6 | 9861 | 1 | 24 | 15 | |
| GSE54993 | PSMD6 | 9861 | 5 | 2 | 63 | |
| GSE54994 | PSMD6 | 9861 | 1 | 33 | 19 | |
| GSE60625 | PSMD6 | 9861 | 3 | 1 | 7 | |
| GSE74703 | PSMD6 | 9861 | 0 | 15 | 21 | |
| GSE74704 | PSMD6 | 9861 | 0 | 12 | 8 | |
| TCGA | PSMD6 | 9861 | 0 | 77 | 19 |
Total number of gains: 12; Total number of losses: 236; Total Number of normals: 240.
Somatic mutations of PSMD6:
Generating mutation plots.
Highly correlated genes for PSMD6:
Showing top 20/451 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMD6 | SH3PXD2A-AS1 | 0.751492 | 3 | 0 | 3 |
| PSMD6 | TMEM43 | 0.722671 | 4 | 0 | 3 |
| PSMD6 | INO80C | 0.716592 | 3 | 0 | 3 |
| PSMD6 | LINC00992 | 0.704899 | 3 | 0 | 3 |
| PSMD6 | ZNF621 | 0.702884 | 4 | 0 | 3 |
| PSMD6 | DMKN | 0.698256 | 3 | 0 | 3 |
| PSMD6 | C15orf48 | 0.692726 | 3 | 0 | 3 |
| PSMD6 | GSKIP | 0.686055 | 4 | 0 | 4 |
| PSMD6 | MED6 | 0.684943 | 3 | 0 | 3 |
| PSMD6 | THOC7 | 0.677427 | 9 | 0 | 7 |
| PSMD6 | IMPACT | 0.677006 | 3 | 0 | 3 |
| PSMD6 | PEX3 | 0.669742 | 9 | 0 | 7 |
| PSMD6 | RWDD2B | 0.664144 | 3 | 0 | 3 |
| PSMD6 | A2ML1 | 0.662266 | 4 | 0 | 3 |
| PSMD6 | NDFIP2 | 0.652828 | 3 | 0 | 3 |
| PSMD6 | CYP3A5 | 0.652167 | 3 | 0 | 3 |
| PSMD6 | GSDMC | 0.652157 | 3 | 0 | 3 |
| PSMD6 | CAPN14 | 0.651805 | 4 | 0 | 3 |
| PSMD6 | ZCCHC9 | 0.650912 | 4 | 0 | 3 |
| PSMD6 | MRPL39 | 0.649418 | 9 | 0 | 8 |
For details and further investigation, click here
