| Full name: REST corepressor 1 | Alias Symbol: COREST|KIAA0071 | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 23186 | HGNC ID: HGNC:17441 | Ensembl Gene: ENSG00000089902 | OMIM ID: 607675 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RCOR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCOR1 | 23186 | 212612_at | -0.2316 | 0.7917 | |
| GSE20347 | RCOR1 | 23186 | 212612_at | -0.6956 | 0.0001 | |
| GSE23400 | RCOR1 | 23186 | 212612_at | -0.3497 | 0.0048 | |
| GSE26886 | RCOR1 | 23186 | 212612_at | -1.5921 | 0.0000 | |
| GSE29001 | RCOR1 | 23186 | 212612_at | -0.1915 | 0.5335 | |
| GSE38129 | RCOR1 | 23186 | 212612_at | -0.2624 | 0.2411 | |
| GSE45670 | RCOR1 | 23186 | 212612_at | 0.1116 | 0.5106 | |
| GSE53622 | RCOR1 | 23186 | 58618 | -0.6228 | 0.0000 | |
| GSE53624 | RCOR1 | 23186 | 58618 | -0.6243 | 0.0000 | |
| GSE63941 | RCOR1 | 23186 | 212612_at | 0.2877 | 0.5622 | |
| GSE77861 | RCOR1 | 23186 | 212612_at | -0.3548 | 0.3839 | |
| GSE97050 | RCOR1 | 23186 | A_33_P3211924 | 0.0637 | 0.8905 | |
| SRP007169 | RCOR1 | 23186 | RNAseq | -0.4416 | 0.2289 | |
| SRP008496 | RCOR1 | 23186 | RNAseq | -0.6452 | 0.0162 | |
| SRP064894 | RCOR1 | 23186 | RNAseq | -0.9000 | 0.0017 | |
| SRP133303 | RCOR1 | 23186 | RNAseq | -0.0245 | 0.8949 | |
| SRP159526 | RCOR1 | 23186 | RNAseq | -0.4979 | 0.2338 | |
| SRP193095 | RCOR1 | 23186 | RNAseq | -0.4452 | 0.0022 | |
| SRP219564 | RCOR1 | 23186 | RNAseq | -0.3080 | 0.6541 | |
| TCGA | RCOR1 | 23186 | RNAseq | 0.1671 | 0.0066 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RCOR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RCOR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCOR1 | 23186 | 11 | 5 | 14 | |
| GSE20123 | RCOR1 | 23186 | 10 | 4 | 16 | |
| GSE43470 | RCOR1 | 23186 | 6 | 4 | 33 | |
| GSE46452 | RCOR1 | 23186 | 18 | 4 | 37 | |
| GSE47630 | RCOR1 | 23186 | 10 | 9 | 21 | |
| GSE54993 | RCOR1 | 23186 | 3 | 8 | 59 | |
| GSE54994 | RCOR1 | 23186 | 21 | 4 | 28 | |
| GSE60625 | RCOR1 | 23186 | 0 | 2 | 9 | |
| GSE74703 | RCOR1 | 23186 | 5 | 3 | 28 | |
| GSE74704 | RCOR1 | 23186 | 5 | 3 | 12 | |
| TCGA | RCOR1 | 23186 | 32 | 20 | 44 |
Total number of gains: 121; Total number of losses: 66; Total Number of normals: 301.
Somatic mutations of RCOR1:
Generating mutation plots.
Highly correlated genes for RCOR1:
Showing top 20/1235 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCOR1 | SLU7 | 0.758252 | 3 | 0 | 3 |
| RCOR1 | SLC10A7 | 0.752857 | 4 | 0 | 3 |
| RCOR1 | IMPACT | 0.75188 | 3 | 0 | 3 |
| RCOR1 | ELOVL1 | 0.745209 | 3 | 0 | 3 |
| RCOR1 | RSPRY1 | 0.743026 | 3 | 0 | 3 |
| RCOR1 | MPZL3 | 0.742797 | 5 | 0 | 5 |
| RCOR1 | ARPC5 | 0.738951 | 3 | 0 | 3 |
| RCOR1 | OXNAD1 | 0.738249 | 3 | 0 | 3 |
| RCOR1 | EGLN1 | 0.738209 | 4 | 0 | 3 |
| RCOR1 | THAP2 | 0.735919 | 4 | 0 | 4 |
| RCOR1 | SNX12 | 0.731854 | 4 | 0 | 3 |
| RCOR1 | CAPN14 | 0.730238 | 4 | 0 | 4 |
| RCOR1 | GGA3 | 0.730012 | 3 | 0 | 3 |
| RCOR1 | CNFN | 0.728456 | 4 | 0 | 4 |
| RCOR1 | KIF21A | 0.727816 | 3 | 0 | 3 |
| RCOR1 | UBA3 | 0.726732 | 4 | 0 | 3 |
| RCOR1 | RALGAPB | 0.725876 | 3 | 0 | 3 |
| RCOR1 | GRHL3 | 0.723047 | 4 | 0 | 4 |
| RCOR1 | VPS25 | 0.721615 | 4 | 0 | 3 |
| RCOR1 | CDS1 | 0.721317 | 7 | 0 | 7 |
For details and further investigation, click here
