| Full name: solute carrier family 12 member 5 | Alias Symbol: KIAA1176|KCC2 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 57468 | HGNC ID: HGNC:13818 | Ensembl Gene: ENSG00000124140 | OMIM ID: 606726 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC12A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC12A5 | 57468 | 210040_at | 0.0415 | 0.8890 | |
| GSE20347 | SLC12A5 | 57468 | 210040_at | 0.1039 | 0.1584 | |
| GSE23400 | SLC12A5 | 57468 | 210040_at | -0.0277 | 0.5991 | |
| GSE26886 | SLC12A5 | 57468 | 210040_at | 0.0822 | 0.5375 | |
| GSE29001 | SLC12A5 | 57468 | 210040_at | -0.0599 | 0.7625 | |
| GSE38129 | SLC12A5 | 57468 | 210040_at | -0.0318 | 0.7225 | |
| GSE45670 | SLC12A5 | 57468 | 210040_at | 0.1309 | 0.1403 | |
| GSE53622 | SLC12A5 | 57468 | 4631 | -1.3260 | 0.0000 | |
| GSE53624 | SLC12A5 | 57468 | 4631 | -1.0329 | 0.0000 | |
| GSE63941 | SLC12A5 | 57468 | 210040_at | 0.1176 | 0.3554 | |
| GSE77861 | SLC12A5 | 57468 | 210040_at | 0.0749 | 0.5467 | |
| TCGA | SLC12A5 | 57468 | RNAseq | -1.0354 | 0.0172 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SLC12A5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC12A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC12A5 | 57468 | 14 | 1 | 15 | |
| GSE20123 | SLC12A5 | 57468 | 14 | 1 | 15 | |
| GSE43470 | SLC12A5 | 57468 | 12 | 1 | 30 | |
| GSE46452 | SLC12A5 | 57468 | 29 | 0 | 30 | |
| GSE47630 | SLC12A5 | 57468 | 24 | 1 | 15 | |
| GSE54993 | SLC12A5 | 57468 | 0 | 17 | 53 | |
| GSE54994 | SLC12A5 | 57468 | 25 | 0 | 28 | |
| GSE60625 | SLC12A5 | 57468 | 0 | 0 | 11 | |
| GSE74703 | SLC12A5 | 57468 | 10 | 1 | 25 | |
| GSE74704 | SLC12A5 | 57468 | 10 | 0 | 10 | |
| TCGA | SLC12A5 | 57468 | 46 | 3 | 47 |
Total number of gains: 184; Total number of losses: 25; Total Number of normals: 279.
Somatic mutations of SLC12A5:
Generating mutation plots.
Highly correlated genes for SLC12A5:
Showing top 20/301 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC12A5 | ZYX | 0.708675 | 4 | 0 | 4 |
| SLC12A5 | APOH | 0.684814 | 3 | 0 | 3 |
| SLC12A5 | MTTP | 0.680241 | 3 | 0 | 3 |
| SLC12A5 | SBNO2 | 0.672399 | 3 | 0 | 3 |
| SLC12A5 | ITIH2 | 0.669978 | 6 | 0 | 5 |
| SLC12A5 | CROCC | 0.662304 | 3 | 0 | 3 |
| SLC12A5 | LIN7A | 0.655806 | 3 | 0 | 3 |
| SLC12A5 | CYSLTR2 | 0.654713 | 4 | 0 | 4 |
| SLC12A5 | LINC00410 | 0.650471 | 3 | 0 | 3 |
| SLC12A5 | CD1B | 0.649783 | 4 | 0 | 3 |
| SLC12A5 | ALAS2 | 0.642131 | 3 | 0 | 3 |
| SLC12A5 | ACSBG2 | 0.640254 | 5 | 0 | 5 |
| SLC12A5 | DCLK1 | 0.638588 | 3 | 0 | 3 |
| SLC12A5 | NPB | 0.634531 | 3 | 0 | 3 |
| SLC12A5 | MC2R | 0.633451 | 7 | 0 | 5 |
| SLC12A5 | CCDC155 | 0.631945 | 5 | 0 | 4 |
| SLC12A5 | SERPINA2 | 0.630022 | 4 | 0 | 4 |
| SLC12A5 | SLC6A13 | 0.629014 | 6 | 0 | 5 |
| SLC12A5 | HS1BP3 | 0.628167 | 4 | 0 | 3 |
| SLC12A5 | NR4A3 | 0.627513 | 3 | 0 | 3 |
For details and further investigation, click here
