| Full name: adaptor related protein complex 1 subunit beta 1 | Alias Symbol: BAM22|AP105A | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 162 | HGNC ID: HGNC:554 | Ensembl Gene: ENSG00000100280 | OMIM ID: 600157 |
| Drug and gene relationship at DGIdb | |||
Expression of AP1B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AP1B1 | 162 | 205423_at | -0.0433 | 0.9323 | |
| GSE20347 | AP1B1 | 162 | 205423_at | -0.6345 | 0.0000 | |
| GSE23400 | AP1B1 | 162 | 205423_at | -0.3028 | 0.0000 | |
| GSE26886 | AP1B1 | 162 | 205423_at | -0.3981 | 0.0213 | |
| GSE29001 | AP1B1 | 162 | 205423_at | -0.5701 | 0.0010 | |
| GSE38129 | AP1B1 | 162 | 205423_at | -0.4672 | 0.0001 | |
| GSE45670 | AP1B1 | 162 | 205423_at | -0.0988 | 0.4411 | |
| GSE53622 | AP1B1 | 162 | 158118 | -0.7963 | 0.0000 | |
| GSE53624 | AP1B1 | 162 | 158118 | -0.5689 | 0.0000 | |
| GSE63941 | AP1B1 | 162 | 205423_at | 0.1762 | 0.5402 | |
| GSE77861 | AP1B1 | 162 | 205423_at | -0.2663 | 0.3681 | |
| GSE97050 | AP1B1 | 162 | A_33_P3317593 | -0.1760 | 0.6193 | |
| SRP007169 | AP1B1 | 162 | RNAseq | -0.9553 | 0.0151 | |
| SRP008496 | AP1B1 | 162 | RNAseq | -1.0396 | 0.0000 | |
| SRP064894 | AP1B1 | 162 | RNAseq | -0.2641 | 0.0718 | |
| SRP133303 | AP1B1 | 162 | RNAseq | -0.5583 | 0.0000 | |
| SRP159526 | AP1B1 | 162 | RNAseq | -0.4304 | 0.0282 | |
| SRP193095 | AP1B1 | 162 | RNAseq | -0.5730 | 0.0000 | |
| SRP219564 | AP1B1 | 162 | RNAseq | 0.0301 | 0.9342 | |
| TCGA | AP1B1 | 162 | RNAseq | -0.0844 | 0.0561 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AP1B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AP1B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AP1B1 | 162 | 3 | 5 | 22 | |
| GSE20123 | AP1B1 | 162 | 3 | 4 | 23 | |
| GSE43470 | AP1B1 | 162 | 4 | 5 | 34 | |
| GSE46452 | AP1B1 | 162 | 31 | 1 | 27 | |
| GSE47630 | AP1B1 | 162 | 8 | 5 | 27 | |
| GSE54993 | AP1B1 | 162 | 3 | 6 | 61 | |
| GSE54994 | AP1B1 | 162 | 11 | 8 | 34 | |
| GSE60625 | AP1B1 | 162 | 5 | 0 | 6 | |
| GSE74703 | AP1B1 | 162 | 4 | 4 | 28 | |
| GSE74704 | AP1B1 | 162 | 0 | 1 | 19 | |
| TCGA | AP1B1 | 162 | 27 | 16 | 53 |
Total number of gains: 99; Total number of losses: 55; Total Number of normals: 334.
Somatic mutations of AP1B1:
Generating mutation plots.
Highly correlated genes for AP1B1:
Showing top 20/1424 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AP1B1 | ARAF | 0.764135 | 3 | 0 | 3 |
| AP1B1 | LRRC28 | 0.760061 | 3 | 0 | 3 |
| AP1B1 | SLC13A2 | 0.753921 | 3 | 0 | 3 |
| AP1B1 | CA13 | 0.751029 | 3 | 0 | 3 |
| AP1B1 | TOLLIP | 0.746237 | 9 | 0 | 9 |
| AP1B1 | TOM1 | 0.744072 | 12 | 0 | 11 |
| AP1B1 | ALKBH7 | 0.743944 | 4 | 0 | 4 |
| AP1B1 | MCTS1 | 0.740935 | 3 | 0 | 3 |
| AP1B1 | ZBTB43 | 0.734454 | 4 | 0 | 4 |
| AP1B1 | MFSD5 | 0.731557 | 11 | 0 | 10 |
| AP1B1 | PLEKHM1 | 0.731097 | 11 | 0 | 11 |
| AP1B1 | TRERF1 | 0.718509 | 3 | 0 | 3 |
| AP1B1 | ASCC2 | 0.718019 | 13 | 0 | 13 |
| AP1B1 | GIPC1 | 0.717366 | 11 | 0 | 10 |
| AP1B1 | SLC10A5 | 0.713017 | 3 | 0 | 3 |
| AP1B1 | USP38 | 0.711616 | 3 | 0 | 3 |
| AP1B1 | HIVEP1 | 0.711521 | 3 | 0 | 3 |
| AP1B1 | RNF135 | 0.70935 | 4 | 0 | 4 |
| AP1B1 | LDHD | 0.708682 | 7 | 0 | 7 |
| AP1B1 | CHMP4B | 0.706198 | 3 | 0 | 3 |
For details and further investigation, click here
