| Full name: Mix paired-like homeobox | Alias Symbol: MILD1|MIXL | ||
| Type: protein-coding gene | Cytoband: 1q42.12 | ||
| Entrez ID: 83881 | HGNC ID: HGNC:13363 | Ensembl Gene: ENSG00000185155 | OMIM ID: 609852 |
| Drug and gene relationship at DGIdb | |||
Expression of MIXL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIXL1 | 83881 | 231746_at | -0.0057 | 0.9879 | |
| GSE26886 | MIXL1 | 83881 | 231746_at | 0.0025 | 0.9870 | |
| GSE45670 | MIXL1 | 83881 | 231746_at | 0.0004 | 0.9983 | |
| GSE53622 | MIXL1 | 83881 | 12233 | -1.2092 | 0.0000 | |
| GSE53624 | MIXL1 | 83881 | 12233 | -1.5983 | 0.0000 | |
| GSE63941 | MIXL1 | 83881 | 231746_at | 0.1970 | 0.2740 | |
| GSE77861 | MIXL1 | 83881 | 231746_at | -0.2057 | 0.1847 | |
| GSE97050 | MIXL1 | 83881 | A_33_P3279550 | 0.0999 | 0.8415 | |
| SRP133303 | MIXL1 | 83881 | RNAseq | 0.3541 | 0.2747 | |
| TCGA | MIXL1 | 83881 | RNAseq | 1.6117 | 0.0344 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by MIXL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MIXL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIXL1 | 83881 | 11 | 0 | 19 | |
| GSE20123 | MIXL1 | 83881 | 11 | 0 | 19 | |
| GSE43470 | MIXL1 | 83881 | 7 | 1 | 35 | |
| GSE46452 | MIXL1 | 83881 | 3 | 1 | 55 | |
| GSE47630 | MIXL1 | 83881 | 15 | 0 | 25 | |
| GSE54993 | MIXL1 | 83881 | 0 | 6 | 64 | |
| GSE54994 | MIXL1 | 83881 | 16 | 0 | 37 | |
| GSE60625 | MIXL1 | 83881 | 0 | 0 | 11 | |
| GSE74703 | MIXL1 | 83881 | 7 | 1 | 28 | |
| GSE74704 | MIXL1 | 83881 | 5 | 0 | 15 | |
| TCGA | MIXL1 | 83881 | 46 | 3 | 47 |
Total number of gains: 121; Total number of losses: 12; Total Number of normals: 355.
Somatic mutations of MIXL1:
Generating mutation plots.
Highly correlated genes for MIXL1:
Showing top 20/280 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIXL1 | OR10G8 | 0.773526 | 3 | 0 | 3 |
| MIXL1 | EXOSC7 | 0.759672 | 3 | 0 | 3 |
| MIXL1 | SLC24A4 | 0.753794 | 3 | 0 | 3 |
| MIXL1 | EPHA10 | 0.728379 | 3 | 0 | 3 |
| MIXL1 | NCR1 | 0.724775 | 3 | 0 | 3 |
| MIXL1 | MAPK8IP2 | 0.721097 | 3 | 0 | 3 |
| MIXL1 | CYP2D6 | 0.714208 | 3 | 0 | 3 |
| MIXL1 | SRCAP | 0.713414 | 3 | 0 | 3 |
| MIXL1 | PNPLA5 | 0.70515 | 3 | 0 | 3 |
| MIXL1 | FBXO34 | 0.692821 | 3 | 0 | 3 |
| MIXL1 | SLC35F3 | 0.691941 | 3 | 0 | 3 |
| MIXL1 | SLC6A18 | 0.687376 | 3 | 0 | 3 |
| MIXL1 | REG3A | 0.686522 | 3 | 0 | 3 |
| MIXL1 | FGFR4 | 0.686203 | 3 | 0 | 3 |
| MIXL1 | FGF17 | 0.683899 | 4 | 0 | 4 |
| MIXL1 | HES2 | 0.682323 | 3 | 0 | 3 |
| MIXL1 | PTGDS | 0.681836 | 3 | 0 | 3 |
| MIXL1 | CLDN9 | 0.681121 | 4 | 0 | 4 |
| MIXL1 | KCNA7 | 0.674001 | 4 | 0 | 3 |
| MIXL1 | KCP | 0.672041 | 3 | 0 | 3 |
For details and further investigation, click here
