| Full name: small integral membrane protein 15 | Alias Symbol: DKFZP686E2158 | ||
| Type: protein-coding gene | Cytoband: 5q12.1 | ||
| Entrez ID: 643155 | HGNC ID: HGNC:33861 | Ensembl Gene: ENSG00000188725 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SMIM15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMIM15 | 643155 | 224740_at | -0.1235 | 0.8680 | |
| GSE26886 | SMIM15 | 643155 | 224740_at | -0.7768 | 0.0025 | |
| GSE45670 | SMIM15 | 643155 | 224740_at | -0.0363 | 0.7813 | |
| GSE53622 | SMIM15 | 643155 | 80093 | -0.4898 | 0.0000 | |
| GSE53624 | SMIM15 | 643155 | 80093 | -0.3718 | 0.0000 | |
| GSE63941 | SMIM15 | 643155 | 224740_at | 0.1131 | 0.7723 | |
| GSE77861 | SMIM15 | 643155 | 224740_at | -0.5246 | 0.0622 | |
| SRP007169 | SMIM15 | 643155 | RNAseq | -0.5309 | 0.2164 | |
| SRP008496 | SMIM15 | 643155 | RNAseq | -0.5587 | 0.0163 | |
| SRP064894 | SMIM15 | 643155 | RNAseq | -0.3647 | 0.0128 | |
| SRP133303 | SMIM15 | 643155 | RNAseq | 0.0469 | 0.7335 | |
| SRP159526 | SMIM15 | 643155 | RNAseq | -0.3101 | 0.4090 | |
| SRP193095 | SMIM15 | 643155 | RNAseq | -0.6583 | 0.0000 | |
| SRP219564 | SMIM15 | 643155 | RNAseq | -0.4471 | 0.1804 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMIM15 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SMIM15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMIM15 | 643155 | 0 | 13 | 17 | |
| GSE20123 | SMIM15 | 643155 | 0 | 13 | 17 | |
| GSE43470 | SMIM15 | 643155 | 1 | 12 | 30 | |
| GSE46452 | SMIM15 | 643155 | 0 | 28 | 31 | |
| GSE47630 | SMIM15 | 643155 | 2 | 17 | 21 | |
| GSE54993 | SMIM15 | 643155 | 8 | 1 | 61 | |
| GSE54994 | SMIM15 | 643155 | 1 | 19 | 33 | |
| GSE60625 | SMIM15 | 643155 | 0 | 0 | 11 | |
| GSE74703 | SMIM15 | 643155 | 1 | 9 | 26 | |
| GSE74704 | SMIM15 | 643155 | 0 | 6 | 14 | |
| TCGA | SMIM15 | 643155 | 5 | 49 | 42 |
Total number of gains: 18; Total number of losses: 167; Total Number of normals: 303.
Somatic mutations of SMIM15:
Generating mutation plots.
Highly correlated genes for SMIM15:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMIM15 | TMEM161B | 0.744147 | 5 | 0 | 4 |
| SMIM15 | FBXL5 | 0.72002 | 3 | 0 | 3 |
| SMIM15 | CD2AP | 0.719879 | 4 | 0 | 3 |
| SMIM15 | PGGT1B | 0.702482 | 5 | 0 | 5 |
| SMIM15 | RIOK2 | 0.692088 | 3 | 0 | 3 |
| SMIM15 | AK3 | 0.688918 | 4 | 0 | 4 |
| SMIM15 | SLC44A3 | 0.681511 | 3 | 0 | 3 |
| SMIM15 | GOLGA4 | 0.678704 | 3 | 0 | 3 |
| SMIM15 | NAT1 | 0.674978 | 3 | 0 | 3 |
| SMIM15 | PRRC1 | 0.674062 | 4 | 0 | 3 |
| SMIM15 | ARPC5L | 0.671799 | 3 | 0 | 3 |
| SMIM15 | WWC1 | 0.671715 | 4 | 0 | 4 |
| SMIM15 | RALGPS2 | 0.667965 | 4 | 0 | 4 |
| SMIM15 | PERP | 0.667697 | 4 | 0 | 3 |
| SMIM15 | SLC26A2 | 0.666128 | 3 | 0 | 3 |
| SMIM15 | LIMK2 | 0.664117 | 4 | 0 | 4 |
| SMIM15 | FAM174A | 0.663759 | 7 | 0 | 6 |
| SMIM15 | ZFYVE16 | 0.663273 | 4 | 0 | 3 |
| SMIM15 | SUMF1 | 0.662895 | 3 | 0 | 3 |
| SMIM15 | DUSP11 | 0.661495 | 3 | 0 | 3 |
For details and further investigation, click here
