| Full name: ETS variant transcription factor 6 | Alias Symbol: TEL | ||
| Type: protein-coding gene | Cytoband: 12p13.2 | ||
| Entrez ID: 2120 | HGNC ID: HGNC:3495 | Ensembl Gene: ENSG00000139083 | OMIM ID: 600618 |
| Drug and gene relationship at DGIdb | |||
Expression of ETV6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETV6 | 2120 | 225764_at | 0.4655 | 0.4838 | |
| GSE20347 | ETV6 | 2120 | 205585_at | -0.0971 | 0.3920 | |
| GSE23400 | ETV6 | 2120 | 205585_at | 0.1123 | 0.0228 | |
| GSE26886 | ETV6 | 2120 | 225764_at | 0.9953 | 0.0094 | |
| GSE29001 | ETV6 | 2120 | 205585_at | 0.2446 | 0.1418 | |
| GSE38129 | ETV6 | 2120 | 205585_at | -0.0016 | 0.9898 | |
| GSE45670 | ETV6 | 2120 | 225764_at | 0.1772 | 0.3340 | |
| GSE53622 | ETV6 | 2120 | 11794 | 0.3029 | 0.0000 | |
| GSE53624 | ETV6 | 2120 | 90045 | 0.2499 | 0.0003 | |
| GSE63941 | ETV6 | 2120 | 225764_at | 0.0137 | 0.9851 | |
| GSE77861 | ETV6 | 2120 | 225764_at | 0.3822 | 0.3006 | |
| GSE97050 | ETV6 | 2120 | A_33_P3356325 | 0.2819 | 0.2495 | |
| SRP007169 | ETV6 | 2120 | RNAseq | 0.5987 | 0.1336 | |
| SRP008496 | ETV6 | 2120 | RNAseq | 0.6164 | 0.0137 | |
| SRP064894 | ETV6 | 2120 | RNAseq | 0.1707 | 0.2541 | |
| SRP133303 | ETV6 | 2120 | RNAseq | 0.2371 | 0.0645 | |
| SRP159526 | ETV6 | 2120 | RNAseq | 0.4701 | 0.3042 | |
| SRP193095 | ETV6 | 2120 | RNAseq | 0.2028 | 0.0832 | |
| SRP219564 | ETV6 | 2120 | RNAseq | 0.0881 | 0.8023 | |
| TCGA | ETV6 | 2120 | RNAseq | 0.1114 | 0.0504 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ETV6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETV6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETV6 | 2120 | 6 | 2 | 22 | |
| GSE20123 | ETV6 | 2120 | 6 | 2 | 22 | |
| GSE43470 | ETV6 | 2120 | 10 | 4 | 29 | |
| GSE46452 | ETV6 | 2120 | 10 | 1 | 48 | |
| GSE47630 | ETV6 | 2120 | 13 | 2 | 25 | |
| GSE54993 | ETV6 | 2120 | 2 | 9 | 59 | |
| GSE54994 | ETV6 | 2120 | 10 | 2 | 41 | |
| GSE60625 | ETV6 | 2120 | 0 | 1 | 10 | |
| GSE74703 | ETV6 | 2120 | 9 | 3 | 24 | |
| GSE74704 | ETV6 | 2120 | 4 | 1 | 15 | |
| TCGA | ETV6 | 2120 | 39 | 7 | 50 |
Total number of gains: 109; Total number of losses: 34; Total Number of normals: 345.
Somatic mutations of ETV6:
Generating mutation plots.
Highly correlated genes for ETV6:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETV6 | GRB2 | 0.797641 | 3 | 0 | 3 |
| ETV6 | MCM3AP | 0.794387 | 3 | 0 | 3 |
| ETV6 | SNRPD2 | 0.781044 | 3 | 0 | 3 |
| ETV6 | PTBP1 | 0.769721 | 3 | 0 | 3 |
| ETV6 | ABCC4 | 0.768917 | 3 | 0 | 3 |
| ETV6 | LRRC34 | 0.765044 | 3 | 0 | 3 |
| ETV6 | SLC35B3 | 0.75889 | 3 | 0 | 3 |
| ETV6 | PRDX4 | 0.758438 | 3 | 0 | 3 |
| ETV6 | MIS12 | 0.75271 | 3 | 0 | 3 |
| ETV6 | ZNF766 | 0.751114 | 3 | 0 | 3 |
| ETV6 | MADD | 0.742027 | 3 | 0 | 3 |
| ETV6 | MRI1 | 0.740988 | 3 | 0 | 3 |
| ETV6 | FXR1 | 0.740775 | 3 | 0 | 3 |
| ETV6 | TMSB15B | 0.737132 | 3 | 0 | 3 |
| ETV6 | FAM120B | 0.735648 | 3 | 0 | 3 |
| ETV6 | LRRC8B | 0.732179 | 3 | 0 | 3 |
| ETV6 | VRK3 | 0.726733 | 3 | 0 | 3 |
| ETV6 | C5orf22 | 0.726351 | 4 | 0 | 3 |
| ETV6 | RPP38 | 0.723432 | 4 | 0 | 4 |
| ETV6 | RRAGB | 0.721514 | 3 | 0 | 3 |
For details and further investigation, click here
