YEATS2

 

Full name: YEATS domain containing 2 Alias Symbol: FLJ10201|FLJ12841|FLJ13308|KIAA1197
Type: protein-coding gene Cytoband: 3q27.1
Entrez ID: 55689 HGNC ID: HGNC:25489 Ensembl Gene: ENSG00000163872 OMIM ID: 613373
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of YEATS2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 YEATS2 55689 221203_s_at 0.8952 0.0117
GSE20347 YEATS2 55689 221203_s_at 1.4731 0.0000
GSE23400 YEATS2 55689 221203_s_at 1.0966 0.0000
GSE26886 YEATS2 55689 221203_s_at 1.3177 0.0000
GSE29001 YEATS2 55689 221203_s_at 1.2893 0.0000
GSE38129 YEATS2 55689 221203_s_at 1.3260 0.0000
GSE45670 YEATS2 55689 221203_s_at 1.1272 0.0001
GSE53622 YEATS2 55689 20124 0.9944 0.0000
GSE53624 YEATS2 55689 20124 1.2365 0.0000
GSE63941 YEATS2 55689 221203_s_at 0.6692 0.1137
GSE77861 YEATS2 55689 1557047_at 0.1817 0.1455
GSE97050 YEATS2 55689 A_33_P3422701 0.0459 0.9029
SRP007169 YEATS2 55689 RNAseq 2.9494 0.0000
SRP008496 YEATS2 55689 RNAseq 2.4708 0.0000
SRP064894 YEATS2 55689 RNAseq 1.3426 0.0000
SRP133303 YEATS2 55689 RNAseq 1.3799 0.0000
SRP159526 YEATS2 55689 RNAseq 1.5018 0.0000
SRP193095 YEATS2 55689 RNAseq 1.3511 0.0000
SRP219564 YEATS2 55689 RNAseq 0.3303 0.2469
TCGA YEATS2 55689 RNAseq 0.3964 0.0000

Upregulated datasets: 13; Downregulated datasets: 0.  

 

Survival by YEATS2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of YEATS2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 YEATS2 55689 25 0 5
GSE20123 YEATS2 55689 25 0 5
GSE43470 YEATS2 55689 24 0 19
GSE46452 YEATS2 55689 19 1 39
GSE47630 YEATS2 55689 27 2 11
GSE54993 YEATS2 55689 1 19 50
GSE54994 YEATS2 55689 41 0 12
GSE60625 YEATS2 55689 0 6 5
GSE74703 YEATS2 55689 20 0 16
GSE74704 YEATS2 55689 17 0 3
TCGA YEATS2 55689 77 0 19

Total number of gains: 276; Total number of losses: 28; Total Number of normals: 184.  

 

Somatic mutations of YEATS2:

 

Generating mutation plots.

 

Highly correlated genes for YEATS2:

 

Showing top 20/641 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
YEATS2ALOX12B0.776082303
YEATS2SOX300.773839303
YEATS2SMPD40.772992303
YEATS2ZNF5260.770879303
YEATS2HOXC90.766909504
YEATS2DOHH0.758219303
YEATS2RFC40.75335412012
YEATS2BLACAT10.747097303
YEATS2MLF10.74133511011
YEATS2SERPINH10.7411321009
YEATS2COLGALT10.73459710010
YEATS2DNMT3B0.73324911011
YEATS2RFT10.729561303
YEATS2MRGBP0.72319811010
YEATS2FBRSL10.721726605
YEATS2CDK160.72149303
YEATS2CLSTN30.716984303
YEATS2RANBP170.714437303
YEATS2DHX90.7142991009
YEATS2CTHRC10.713995505

For details and further investigation, click here