| Full name: layilin | Alias Symbol: FLJ30977|FLJ31092 | ||
| Type: protein-coding gene | Cytoband: 11q23.1 | ||
| Entrez ID: 143903 | HGNC ID: HGNC:29471 | Ensembl Gene: ENSG00000204381 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LAYN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LAYN | 143903 | 228080_at | 0.8588 | 0.3997 | |
| GSE26886 | LAYN | 143903 | 228080_at | 1.7250 | 0.0012 | |
| GSE45670 | LAYN | 143903 | 228080_at | 0.4963 | 0.1535 | |
| GSE53622 | LAYN | 143903 | 73248 | 0.9060 | 0.0000 | |
| GSE53624 | LAYN | 143903 | 73248 | 1.1277 | 0.0000 | |
| GSE63941 | LAYN | 143903 | 228080_at | -4.8661 | 0.0005 | |
| GSE77861 | LAYN | 143903 | 228080_at | 1.7357 | 0.0295 | |
| GSE97050 | LAYN | 143903 | A_23_P127565 | 0.2262 | 0.4919 | |
| SRP007169 | LAYN | 143903 | RNAseq | 0.3720 | 0.5909 | |
| SRP008496 | LAYN | 143903 | RNAseq | 0.5398 | 0.2468 | |
| SRP064894 | LAYN | 143903 | RNAseq | 0.4521 | 0.0833 | |
| SRP133303 | LAYN | 143903 | RNAseq | 1.0593 | 0.0030 | |
| SRP159526 | LAYN | 143903 | RNAseq | 1.3896 | 0.0000 | |
| SRP193095 | LAYN | 143903 | RNAseq | 1.1435 | 0.0000 | |
| SRP219564 | LAYN | 143903 | RNAseq | 0.7795 | 0.2207 | |
| TCGA | LAYN | 143903 | RNAseq | 0.4115 | 0.0274 |
Upregulated datasets: 6; Downregulated datasets: 1.
Survival by LAYN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LAYN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LAYN | 143903 | 0 | 12 | 18 | |
| GSE20123 | LAYN | 143903 | 0 | 12 | 18 | |
| GSE43470 | LAYN | 143903 | 2 | 6 | 35 | |
| GSE46452 | LAYN | 143903 | 3 | 26 | 30 | |
| GSE47630 | LAYN | 143903 | 2 | 19 | 19 | |
| GSE54993 | LAYN | 143903 | 10 | 0 | 60 | |
| GSE54994 | LAYN | 143903 | 5 | 19 | 29 | |
| GSE60625 | LAYN | 143903 | 0 | 3 | 8 | |
| GSE74703 | LAYN | 143903 | 1 | 4 | 31 | |
| GSE74704 | LAYN | 143903 | 0 | 8 | 12 | |
| TCGA | LAYN | 143903 | 6 | 48 | 42 |
Total number of gains: 29; Total number of losses: 157; Total Number of normals: 302.
Somatic mutations of LAYN:
Generating mutation plots.
Highly correlated genes for LAYN:
Showing top 20/258 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LAYN | FPR1 | 0.770209 | 3 | 0 | 3 |
| LAYN | ARNT2 | 0.768453 | 3 | 0 | 3 |
| LAYN | SLC35B4 | 0.72828 | 3 | 0 | 3 |
| LAYN | ASTN2 | 0.709587 | 3 | 0 | 3 |
| LAYN | KRT25 | 0.704212 | 3 | 0 | 3 |
| LAYN | LYPD6 | 0.700106 | 3 | 0 | 3 |
| LAYN | GDF15 | 0.687925 | 3 | 0 | 3 |
| LAYN | HSD17B14 | 0.68728 | 3 | 0 | 3 |
| LAYN | SIRPA | 0.680434 | 5 | 0 | 3 |
| LAYN | BAALC | 0.679576 | 4 | 0 | 4 |
| LAYN | MTERF3 | 0.676115 | 3 | 0 | 3 |
| LAYN | DFFB | 0.671488 | 3 | 0 | 3 |
| LAYN | ANKH | 0.665523 | 3 | 0 | 3 |
| LAYN | NID2 | 0.663687 | 5 | 0 | 4 |
| LAYN | NSUN6 | 0.661835 | 3 | 0 | 3 |
| LAYN | RASGRF2 | 0.661276 | 4 | 0 | 3 |
| LAYN | CEP85L | 0.657301 | 3 | 0 | 3 |
| LAYN | USP51 | 0.655333 | 3 | 0 | 3 |
| LAYN | TYRP1 | 0.652711 | 3 | 0 | 3 |
| LAYN | CSGALNACT2 | 0.651504 | 6 | 0 | 5 |
For details and further investigation, click here
