| Full name: solute carrier family 39 member 8 | Alias Symbol: BIGM103 | ||
| Type: protein-coding gene | Cytoband: 4q24 | ||
| Entrez ID: 64116 | HGNC ID: HGNC:20862 | Ensembl Gene: ENSG00000138821 | OMIM ID: 608732 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC39A8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC39A8 | 64116 | 209267_s_at | 1.3483 | 0.3118 | |
| GSE20347 | SLC39A8 | 64116 | 209267_s_at | 0.8025 | 0.0207 | |
| GSE23400 | SLC39A8 | 64116 | 219869_s_at | 0.1197 | 0.0144 | |
| GSE26886 | SLC39A8 | 64116 | 219869_s_at | 0.4810 | 0.1380 | |
| GSE29001 | SLC39A8 | 64116 | 209267_s_at | 1.0748 | 0.0619 | |
| GSE38129 | SLC39A8 | 64116 | 209267_s_at | 0.9550 | 0.0006 | |
| GSE45670 | SLC39A8 | 64116 | 209267_s_at | 0.1260 | 0.8057 | |
| GSE53622 | SLC39A8 | 64116 | 77011 | 0.6586 | 0.0000 | |
| GSE53624 | SLC39A8 | 64116 | 77011 | 0.9060 | 0.0000 | |
| GSE63941 | SLC39A8 | 64116 | 209267_s_at | -1.1291 | 0.4024 | |
| GSE77861 | SLC39A8 | 64116 | 228945_s_at | -0.0209 | 0.8255 | |
| GSE97050 | SLC39A8 | 64116 | A_23_P41424 | 0.6155 | 0.2727 | |
| SRP007169 | SLC39A8 | 64116 | RNAseq | 1.7262 | 0.0024 | |
| SRP008496 | SLC39A8 | 64116 | RNAseq | 1.4715 | 0.0001 | |
| SRP064894 | SLC39A8 | 64116 | RNAseq | 0.6761 | 0.0811 | |
| SRP133303 | SLC39A8 | 64116 | RNAseq | 0.4690 | 0.0848 | |
| SRP159526 | SLC39A8 | 64116 | RNAseq | 0.8781 | 0.0217 | |
| SRP193095 | SLC39A8 | 64116 | RNAseq | 0.9949 | 0.0002 | |
| SRP219564 | SLC39A8 | 64116 | RNAseq | 1.6310 | 0.0002 | |
| TCGA | SLC39A8 | 64116 | RNAseq | 0.2697 | 0.0102 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SLC39A8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC39A8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC39A8 | 64116 | 1 | 12 | 17 | |
| GSE20123 | SLC39A8 | 64116 | 1 | 12 | 17 | |
| GSE43470 | SLC39A8 | 64116 | 0 | 13 | 30 | |
| GSE46452 | SLC39A8 | 64116 | 1 | 36 | 22 | |
| GSE47630 | SLC39A8 | 64116 | 0 | 20 | 20 | |
| GSE54993 | SLC39A8 | 64116 | 9 | 0 | 61 | |
| GSE54994 | SLC39A8 | 64116 | 1 | 10 | 42 | |
| GSE60625 | SLC39A8 | 64116 | 0 | 3 | 8 | |
| GSE74703 | SLC39A8 | 64116 | 0 | 11 | 25 | |
| GSE74704 | SLC39A8 | 64116 | 0 | 6 | 14 | |
| TCGA | SLC39A8 | 64116 | 8 | 39 | 49 |
Total number of gains: 21; Total number of losses: 162; Total Number of normals: 305.
Somatic mutations of SLC39A8:
Generating mutation plots.
Highly correlated genes for SLC39A8:
Showing top 20/682 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC39A8 | MYO3B | 0.830374 | 3 | 0 | 3 |
| SLC39A8 | CDCA2 | 0.781027 | 3 | 0 | 3 |
| SLC39A8 | ZMYM1 | 0.749754 | 3 | 0 | 3 |
| SLC39A8 | CMTM7 | 0.716633 | 3 | 0 | 3 |
| SLC39A8 | FCGR3A | 0.702115 | 3 | 0 | 3 |
| SLC39A8 | RCN2 | 0.701025 | 4 | 0 | 4 |
| SLC39A8 | PGM2L1 | 0.69865 | 4 | 0 | 4 |
| SLC39A8 | HAUS7 | 0.677839 | 4 | 0 | 3 |
| SLC39A8 | CEP128 | 0.673276 | 5 | 0 | 4 |
| SLC39A8 | TSNAX | 0.67286 | 5 | 0 | 5 |
| SLC39A8 | MAGOHB | 0.672355 | 4 | 0 | 3 |
| SLC39A8 | FOXN2 | 0.670809 | 4 | 0 | 3 |
| SLC39A8 | TUSC3 | 0.667742 | 5 | 0 | 5 |
| SLC39A8 | CERKL | 0.667119 | 3 | 0 | 3 |
| SLC39A8 | THOC6 | 0.666118 | 5 | 0 | 5 |
| SLC39A8 | EMB | 0.661512 | 4 | 0 | 3 |
| SLC39A8 | HSPA13 | 0.661196 | 8 | 0 | 8 |
| SLC39A8 | ILF3 | 0.660099 | 3 | 0 | 3 |
| SLC39A8 | RAD17 | 0.65835 | 3 | 0 | 3 |
| SLC39A8 | FBXO11 | 0.656866 | 3 | 0 | 3 |
For details and further investigation, click here
