| Full name: myosin IIIB | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 140469 | HGNC ID: HGNC:15576 | Ensembl Gene: ENSG00000071909 | OMIM ID: 610040 |
| Drug and gene relationship at DGIdb | |||
Expression of MYO3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYO3B | 140469 | 1552578_a_at | 0.3578 | 0.7364 | |
| GSE26886 | MYO3B | 140469 | 1560788_at | 0.5258 | 0.0065 | |
| GSE45670 | MYO3B | 140469 | 1555257_a_at | 0.0454 | 0.7576 | |
| GSE53622 | MYO3B | 140469 | 79557 | -0.0791 | 0.8228 | |
| GSE53624 | MYO3B | 140469 | 96273 | -0.3520 | 0.1017 | |
| GSE63941 | MYO3B | 140469 | 1560788_at | -0.0916 | 0.7023 | |
| GSE77861 | MYO3B | 140469 | 1555257_a_at | -0.0961 | 0.1526 | |
| GSE97050 | MYO3B | 140469 | A_23_P417853 | 0.5347 | 0.1873 | |
| SRP007169 | MYO3B | 140469 | RNAseq | 0.2408 | 0.7468 | |
| SRP064894 | MYO3B | 140469 | RNAseq | 0.9175 | 0.0377 | |
| SRP133303 | MYO3B | 140469 | RNAseq | 0.4274 | 0.0607 | |
| SRP159526 | MYO3B | 140469 | RNAseq | -0.5647 | 0.1579 | |
| SRP193095 | MYO3B | 140469 | RNAseq | 0.7218 | 0.0058 | |
| SRP219564 | MYO3B | 140469 | RNAseq | 0.3071 | 0.6437 | |
| TCGA | MYO3B | 140469 | RNAseq | 1.1822 | 0.0246 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MYO3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYO3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYO3B | 140469 | 8 | 0 | 22 | |
| GSE20123 | MYO3B | 140469 | 8 | 0 | 22 | |
| GSE43470 | MYO3B | 140469 | 5 | 1 | 37 | |
| GSE46452 | MYO3B | 140469 | 1 | 4 | 54 | |
| GSE47630 | MYO3B | 140469 | 5 | 3 | 32 | |
| GSE54993 | MYO3B | 140469 | 0 | 5 | 65 | |
| GSE54994 | MYO3B | 140469 | 11 | 3 | 39 | |
| GSE60625 | MYO3B | 140469 | 0 | 3 | 8 | |
| GSE74703 | MYO3B | 140469 | 4 | 1 | 31 | |
| GSE74704 | MYO3B | 140469 | 5 | 0 | 15 | |
| TCGA | MYO3B | 140469 | 25 | 9 | 62 |
Total number of gains: 72; Total number of losses: 29; Total Number of normals: 387.
Somatic mutations of MYO3B:
Generating mutation plots.
Highly correlated genes for MYO3B:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYO3B | ZNF669 | 0.845341 | 3 | 0 | 3 |
| MYO3B | SLC39A8 | 0.830374 | 3 | 0 | 3 |
| MYO3B | SDR39U1 | 0.785305 | 3 | 0 | 3 |
| MYO3B | PPP2R3A | 0.76858 | 3 | 0 | 3 |
| MYO3B | INTS4 | 0.768232 | 3 | 0 | 3 |
| MYO3B | CEP128 | 0.754952 | 3 | 0 | 3 |
| MYO3B | IPP | 0.750512 | 3 | 0 | 3 |
| MYO3B | IRAK1BP1 | 0.742914 | 3 | 0 | 3 |
| MYO3B | NEK6 | 0.718359 | 3 | 0 | 3 |
| MYO3B | KANK4 | 0.711044 | 3 | 0 | 3 |
| MYO3B | PKN3 | 0.707308 | 3 | 0 | 3 |
| MYO3B | BAIAP2L2 | 0.70607 | 3 | 0 | 3 |
| MYO3B | TMEM92 | 0.703758 | 3 | 0 | 3 |
| MYO3B | DHX37 | 0.694619 | 3 | 0 | 3 |
| MYO3B | VRK1 | 0.69148 | 3 | 0 | 3 |
| MYO3B | INHBE | 0.687928 | 3 | 0 | 3 |
| MYO3B | IL17RD | 0.687656 | 3 | 0 | 3 |
| MYO3B | SLC6A9 | 0.687276 | 3 | 0 | 3 |
| MYO3B | FAM86C1 | 0.686724 | 3 | 0 | 3 |
| MYO3B | RFC1 | 0.682609 | 3 | 0 | 3 |
For details and further investigation, click here
