HSPA13

 

Full name: heat shock protein family A (Hsp70) member 13 Alias Symbol: 
Type: protein-coding gene Cytoband: 21q11.2
Entrez ID: 6782 HGNC ID: HGNC:11375 Ensembl Gene: ENSG00000155304 OMIM ID: 601100
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of HSPA13:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HSPA13 6782 202557_at 0.3069 0.5940
GSE20347 HSPA13 6782 202557_at 0.7270 0.0015
GSE23400 HSPA13 6782 202557_at 0.5710 0.0000
GSE26886 HSPA13 6782 202558_s_at 0.4960 0.1711
GSE29001 HSPA13 6782 202557_at 0.9981 0.0102
GSE38129 HSPA13 6782 202557_at 0.6713 0.0015
GSE45670 HSPA13 6782 202557_at 0.3224 0.2540
GSE53622 HSPA13 6782 54862 0.4301 0.0001
GSE53624 HSPA13 6782 54862 0.7315 0.0000
GSE63941 HSPA13 6782 202557_at -0.8644 0.3768
GSE77861 HSPA13 6782 202557_at 0.6927 0.0291
GSE97050 HSPA13 6782 A_24_P134392 0.1705 0.5026
SRP007169 HSPA13 6782 RNAseq 2.2462 0.0009
SRP008496 HSPA13 6782 RNAseq 1.8909 0.0000
SRP064894 HSPA13 6782 RNAseq 0.7556 0.0049
SRP133303 HSPA13 6782 RNAseq 0.7925 0.0000
SRP159526 HSPA13 6782 RNAseq 0.6841 0.0108
SRP193095 HSPA13 6782 RNAseq 0.4885 0.0126
SRP219564 HSPA13 6782 RNAseq 0.4300 0.3683
TCGA HSPA13 6782 RNAseq 0.0076 0.8943

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by HSPA13 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HSPA13:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HSPA13 6782 2 9 19
GSE20123 HSPA13 6782 2 9 19
GSE43470 HSPA13 6782 2 11 30
GSE46452 HSPA13 6782 1 22 36
GSE47630 HSPA13 6782 6 17 17
GSE54993 HSPA13 6782 9 1 60
GSE54994 HSPA13 6782 3 10 40
GSE60625 HSPA13 6782 0 0 11
GSE74703 HSPA13 6782 2 8 26
GSE74704 HSPA13 6782 2 6 12
TCGA HSPA13 6782 14 40 42

Total number of gains: 43; Total number of losses: 133; Total Number of normals: 312.  

 

Somatic mutations of HSPA13:

 

Generating mutation plots.

 

Highly correlated genes for HSPA13:

 

Showing top 20/1185 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HSPA13CEP1520.725003303
HSPA13FAM76B0.723999303
HSPA13FCGR3A0.72278303
HSPA13SLC41A10.722469505
HSPA13EXOC80.711604303
HSPA13RELL10.701887404
HSPA13NEFL0.693706303
HSPA13SLFN110.692054505
HSPA13MMD0.69115411011
HSPA13C16orf720.690101303
HSPA13GTPBP30.687476303
HSPA13CENPH0.683548403
HSPA13CERKL0.681043303
HSPA13C7orf500.681039303
HSPA13TGFBR10.681001403
HSPA13DNAH140.679851404
HSPA13ACVR10.6783911010
HSPA13BORA0.675534605
HSPA13RCBTB10.675002806
HSPA13POC50.674383504

For details and further investigation, click here