| Full name: reticulocalbin 2 | Alias Symbol: ERC-55|E6BP|ERC55|TCBP49 | ||
| Type: protein-coding gene | Cytoband: 15q24.3 | ||
| Entrez ID: 5955 | HGNC ID: HGNC:9935 | Ensembl Gene: ENSG00000117906 | OMIM ID: 602584 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RCN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCN2 | 5955 | 201486_at | 0.4342 | 0.3289 | |
| GSE20347 | RCN2 | 5955 | 201485_s_at | 0.7140 | 0.0002 | |
| GSE23400 | RCN2 | 5955 | 201485_s_at | 0.7554 | 0.0000 | |
| GSE26886 | RCN2 | 5955 | 201486_at | 0.9118 | 0.0002 | |
| GSE29001 | RCN2 | 5955 | 201486_at | 0.5722 | 0.1744 | |
| GSE38129 | RCN2 | 5955 | 201486_at | 0.7600 | 0.0000 | |
| GSE45670 | RCN2 | 5955 | 201486_at | 0.2714 | 0.0627 | |
| GSE63941 | RCN2 | 5955 | 201486_at | -1.1059 | 0.0014 | |
| GSE77861 | RCN2 | 5955 | 201486_at | 0.4259 | 0.1818 | |
| GSE97050 | RCN2 | 5955 | A_32_P175539 | 0.6885 | 0.0781 | |
| SRP007169 | RCN2 | 5955 | RNAseq | -0.0243 | 0.9509 | |
| SRP008496 | RCN2 | 5955 | RNAseq | 0.4394 | 0.0659 | |
| SRP064894 | RCN2 | 5955 | RNAseq | 0.4559 | 0.0090 | |
| SRP133303 | RCN2 | 5955 | RNAseq | 0.8986 | 0.0000 | |
| SRP159526 | RCN2 | 5955 | RNAseq | 1.2117 | 0.0000 | |
| SRP193095 | RCN2 | 5955 | RNAseq | 0.4778 | 0.0008 | |
| SRP219564 | RCN2 | 5955 | RNAseq | 0.1194 | 0.6780 | |
| TCGA | RCN2 | 5955 | RNAseq | 0.1956 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by RCN2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RCN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCN2 | 5955 | 8 | 2 | 20 | |
| GSE20123 | RCN2 | 5955 | 8 | 2 | 20 | |
| GSE43470 | RCN2 | 5955 | 4 | 5 | 34 | |
| GSE46452 | RCN2 | 5955 | 3 | 7 | 49 | |
| GSE47630 | RCN2 | 5955 | 8 | 10 | 22 | |
| GSE54993 | RCN2 | 5955 | 5 | 6 | 59 | |
| GSE54994 | RCN2 | 5955 | 5 | 6 | 42 | |
| GSE60625 | RCN2 | 5955 | 4 | 0 | 7 | |
| GSE74703 | RCN2 | 5955 | 4 | 3 | 29 | |
| GSE74704 | RCN2 | 5955 | 4 | 2 | 14 | |
| TCGA | RCN2 | 5955 | 15 | 15 | 66 |
Total number of gains: 68; Total number of losses: 58; Total Number of normals: 362.
Somatic mutations of RCN2:
Generating mutation plots.
Highly correlated genes for RCN2:
Showing top 20/1403 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCN2 | ZNF689 | 0.857686 | 3 | 0 | 3 |
| RCN2 | HYLS1 | 0.81183 | 3 | 0 | 3 |
| RCN2 | SLC16A4 | 0.798663 | 3 | 0 | 3 |
| RCN2 | LETM2 | 0.788237 | 3 | 0 | 3 |
| RCN2 | TRUB1 | 0.773651 | 4 | 0 | 4 |
| RCN2 | MASTL | 0.769412 | 4 | 0 | 4 |
| RCN2 | PLEKHM3 | 0.768665 | 3 | 0 | 3 |
| RCN2 | ZNF25 | 0.762211 | 4 | 0 | 4 |
| RCN2 | DNTTIP1 | 0.757164 | 3 | 0 | 3 |
| RCN2 | SLC30A7 | 0.751533 | 4 | 0 | 4 |
| RCN2 | EBF1 | 0.748958 | 3 | 0 | 3 |
| RCN2 | PIGS | 0.748417 | 3 | 0 | 3 |
| RCN2 | UBTD2 | 0.747698 | 3 | 0 | 3 |
| RCN2 | SAMM50 | 0.744472 | 3 | 0 | 3 |
| RCN2 | MORF4L1 | 0.742041 | 9 | 0 | 9 |
| RCN2 | BOD1 | 0.741093 | 4 | 0 | 3 |
| RCN2 | BTBD6 | 0.741007 | 3 | 0 | 3 |
| RCN2 | ENG | 0.739819 | 3 | 0 | 3 |
| RCN2 | USP42 | 0.737224 | 4 | 0 | 3 |
| RCN2 | C1orf122 | 0.735272 | 3 | 0 | 3 |
For details and further investigation, click here
