| Full name: ceramide kinase like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q31.3 | ||
| Entrez ID: 375298 | HGNC ID: HGNC:21699 | Ensembl Gene: ENSG00000188452 | OMIM ID: 608381 |
| Drug and gene relationship at DGIdb | |||
Expression of CERKL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | CERKL | 375298 | 94558 | 0.6865 | 0.0000 | |
| GSE53624 | CERKL | 375298 | 94558 | 0.4296 | 0.0007 | |
| GSE97050 | CERKL | 375298 | A_33_P3355538 | 0.0602 | 0.8918 | |
| TCGA | CERKL | 375298 | RNAseq | 0.1574 | 0.4103 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CERKL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CERKL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CERKL | 375298 | 5 | 1 | 24 | |
| GSE20123 | CERKL | 375298 | 5 | 1 | 24 | |
| GSE43470 | CERKL | 375298 | 5 | 1 | 37 | |
| GSE46452 | CERKL | 375298 | 1 | 4 | 54 | |
| GSE47630 | CERKL | 375298 | 4 | 4 | 32 | |
| GSE54993 | CERKL | 375298 | 0 | 5 | 65 | |
| GSE54994 | CERKL | 375298 | 12 | 5 | 36 | |
| GSE60625 | CERKL | 375298 | 0 | 3 | 8 | |
| GSE74703 | CERKL | 375298 | 4 | 1 | 31 | |
| GSE74704 | CERKL | 375298 | 2 | 1 | 17 | |
| TCGA | CERKL | 375298 | 27 | 7 | 62 |
Total number of gains: 65; Total number of losses: 33; Total Number of normals: 390.
Somatic mutations of CERKL:
Generating mutation plots.
Highly correlated genes for CERKL:
Showing top 20/271 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CERKL | C1QA | 0.797653 | 3 | 0 | 3 |
| CERKL | SPI1 | 0.796741 | 3 | 0 | 3 |
| CERKL | CYBA | 0.782797 | 3 | 0 | 3 |
| CERKL | LCP2 | 0.781256 | 3 | 0 | 3 |
| CERKL | ADAMDEC1 | 0.77869 | 3 | 0 | 3 |
| CERKL | CD84 | 0.776355 | 3 | 0 | 3 |
| CERKL | MILR1 | 0.774087 | 3 | 0 | 3 |
| CERKL | KCNAB2 | 0.762393 | 3 | 0 | 3 |
| CERKL | SH2B3 | 0.761219 | 3 | 0 | 3 |
| CERKL | CDC42SE2 | 0.760129 | 3 | 0 | 3 |
| CERKL | HVCN1 | 0.75996 | 3 | 0 | 3 |
| CERKL | LAPTM5 | 0.759505 | 3 | 0 | 3 |
| CERKL | LY96 | 0.75705 | 3 | 0 | 3 |
| CERKL | HLA-DMB | 0.756606 | 3 | 0 | 3 |
| CERKL | ST8SIA4 | 0.756393 | 3 | 0 | 3 |
| CERKL | IRF8 | 0.755698 | 3 | 0 | 3 |
| CERKL | DOK1 | 0.755156 | 3 | 0 | 3 |
| CERKL | CD14 | 0.753482 | 3 | 0 | 3 |
| CERKL | RASGRP3 | 0.753211 | 3 | 0 | 3 |
| CERKL | IGSF6 | 0.751907 | 3 | 0 | 3 |
For details and further investigation, click here
