| Full name: solute carrier family 4 member 3 | Alias Symbol: AE3|SLC2C | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 6508 | HGNC ID: HGNC:11029 | Ensembl Gene: ENSG00000114923 | OMIM ID: 106195 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC4A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC4A3 | 6508 | 205918_at | -0.0370 | 0.9589 | |
| GSE20347 | SLC4A3 | 6508 | 205918_at | 0.1369 | 0.2656 | |
| GSE23400 | SLC4A3 | 6508 | 205918_at | 0.0122 | 0.8782 | |
| GSE26886 | SLC4A3 | 6508 | 205918_at | 0.6599 | 0.0000 | |
| GSE29001 | SLC4A3 | 6508 | 205918_at | 0.3944 | 0.1140 | |
| GSE38129 | SLC4A3 | 6508 | 205918_at | -0.0112 | 0.9546 | |
| GSE45670 | SLC4A3 | 6508 | 205918_at | 0.3809 | 0.0259 | |
| GSE53622 | SLC4A3 | 6508 | 129411 | -4.2180 | 0.0000 | |
| GSE53624 | SLC4A3 | 6508 | 129411 | -4.7273 | 0.0000 | |
| GSE63941 | SLC4A3 | 6508 | 205918_at | 0.0176 | 0.9503 | |
| GSE77861 | SLC4A3 | 6508 | 205918_at | 0.2158 | 0.2108 | |
| GSE97050 | SLC4A3 | 6508 | A_23_P39647 | -0.3676 | 0.3041 | |
| SRP007169 | SLC4A3 | 6508 | RNAseq | 2.1415 | 0.0057 | |
| SRP064894 | SLC4A3 | 6508 | RNAseq | 1.4765 | 0.0000 | |
| SRP133303 | SLC4A3 | 6508 | RNAseq | 0.7892 | 0.0062 | |
| SRP159526 | SLC4A3 | 6508 | RNAseq | 1.4725 | 0.0069 | |
| SRP193095 | SLC4A3 | 6508 | RNAseq | 1.8098 | 0.0000 | |
| SRP219564 | SLC4A3 | 6508 | RNAseq | 0.1206 | 0.8603 | |
| TCGA | SLC4A3 | 6508 | RNAseq | 0.1957 | 0.1430 |
Upregulated datasets: 4; Downregulated datasets: 2.
Survival by SLC4A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC4A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC4A3 | 6508 | 2 | 14 | 14 | |
| GSE20123 | SLC4A3 | 6508 | 2 | 13 | 15 | |
| GSE43470 | SLC4A3 | 6508 | 1 | 6 | 36 | |
| GSE46452 | SLC4A3 | 6508 | 0 | 5 | 54 | |
| GSE47630 | SLC4A3 | 6508 | 4 | 5 | 31 | |
| GSE54993 | SLC4A3 | 6508 | 1 | 2 | 67 | |
| GSE54994 | SLC4A3 | 6508 | 8 | 9 | 36 | |
| GSE60625 | SLC4A3 | 6508 | 0 | 3 | 8 | |
| GSE74703 | SLC4A3 | 6508 | 1 | 5 | 30 | |
| GSE74704 | SLC4A3 | 6508 | 2 | 7 | 11 | |
| TCGA | SLC4A3 | 6508 | 12 | 26 | 58 |
Total number of gains: 33; Total number of losses: 95; Total Number of normals: 360.
Somatic mutations of SLC4A3:
Generating mutation plots.
Highly correlated genes for SLC4A3:
Showing top 20/158 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC4A3 | RYR1 | 0.784285 | 3 | 0 | 3 |
| SLC4A3 | SFRP5 | 0.753116 | 3 | 0 | 3 |
| SLC4A3 | OR10G8 | 0.748028 | 3 | 0 | 3 |
| SLC4A3 | BTBD19 | 0.738744 | 4 | 0 | 3 |
| SLC4A3 | BARHL2 | 0.722471 | 3 | 0 | 3 |
| SLC4A3 | GRASP | 0.704565 | 3 | 0 | 3 |
| SLC4A3 | HAAO | 0.698601 | 3 | 0 | 3 |
| SLC4A3 | OR10G3 | 0.696756 | 3 | 0 | 3 |
| SLC4A3 | NTNG1 | 0.694862 | 4 | 0 | 3 |
| SLC4A3 | CCDC50 | 0.692839 | 5 | 0 | 4 |
| SLC4A3 | HRCT1 | 0.690285 | 5 | 0 | 5 |
| SLC4A3 | C14orf180 | 0.690222 | 3 | 0 | 3 |
| SLC4A3 | KRTAP6-3 | 0.689555 | 3 | 0 | 3 |
| SLC4A3 | PHF12 | 0.669533 | 4 | 0 | 3 |
| SLC4A3 | MASP2 | 0.660416 | 4 | 0 | 3 |
| SLC4A3 | TEN1 | 0.660077 | 3 | 0 | 3 |
| SLC4A3 | INS | 0.654242 | 3 | 0 | 3 |
| SLC4A3 | TOMM34 | 0.647402 | 3 | 0 | 3 |
| SLC4A3 | FAM187B | 0.634299 | 3 | 0 | 3 |
| SLC4A3 | NT5DC3 | 0.633903 | 7 | 0 | 6 |
For details and further investigation, click here
