GRASP

 

Full name: general receptor for phosphoinositides 1 associated scaffold protein Alias Symbol: Tamalin
Type: protein-coding gene Cytoband: 12q13.13
Entrez ID: 160622 HGNC ID: HGNC:18707 Ensembl Gene: ENSG00000161835 OMIM ID: 612027
Drug and gene relationship at DGIdb

 

Expression of GRASP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GRASP 160622 228263_at -0.0537 0.8544
GSE26886 GRASP 160622 228263_at 0.5023 0.0004
GSE45670 GRASP 160622 228263_at -0.2371 0.0071
GSE53622 GRASP 160622 1792 -1.6990 0.0000
GSE53624 GRASP 160622 1792 -1.6530 0.0000
GSE63941 GRASP 160622 228263_at -0.1401 0.4302
GSE77861 GRASP 160622 228263_at 0.0300 0.9041
GSE97050 GRASP 160622 A_33_P3299416 -1.3883 0.0620
SRP007169 GRASP 160622 RNAseq -0.5240 0.3340
SRP064894 GRASP 160622 RNAseq 0.0538 0.8832
SRP133303 GRASP 160622 RNAseq -0.6577 0.0030
SRP159526 GRASP 160622 RNAseq 0.1983 0.6434
SRP193095 GRASP 160622 RNAseq 0.6955 0.0042
SRP219564 GRASP 160622 RNAseq -0.5846 0.3519
TCGA GRASP 160622 RNAseq -0.3790 0.0043

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by GRASP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GRASP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GRASP 160622 8 2 20
GSE20123 GRASP 160622 8 1 21
GSE43470 GRASP 160622 4 0 39
GSE46452 GRASP 160622 7 1 51
GSE47630 GRASP 160622 10 2 28
GSE54993 GRASP 160622 0 5 65
GSE54994 GRASP 160622 3 2 48
GSE60625 GRASP 160622 0 0 11
GSE74703 GRASP 160622 3 0 33
GSE74704 GRASP 160622 5 1 14
TCGA GRASP 160622 13 11 72

Total number of gains: 61; Total number of losses: 25; Total Number of normals: 402.  


 

Somatic mutations of GRASP:

 

Generating mutation plots.

 

Highly correlated genes for GRASP:

 

Showing top 20/472 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GRASPCLEC3B0.775746303
GRASPRILP0.744536303
GRASPTMEM255B0.738213404
GRASPCOL26A10.733643303
GRASPCABIN10.710392404
GRASPSLC4A30.704565303
GRASPCYP21A20.704492303
GRASPVMAC0.703997303
GRASPNCKIPSD0.699801303
GRASPKCNJ100.699042303
GRASPPI160.694327707
GRASPTRAF3IP2-AS10.692505303
GRASPTRIOBP0.692464403
GRASPARID5A0.690589504
GRASPC1QTNF70.68682303
GRASPMZF10.684876303
GRASPDNASE1L20.682256303
GRASPCA130.68054303
GRASPGPR1620.680438303
GRASPPCGF20.679206404

For details and further investigation, click here