| Full name: histidine rich carboxyl terminus 1 | Alias Symbol: LGLL338|PRO537|UNQ338 | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 646962 | HGNC ID: HGNC:33872 | Ensembl Gene: ENSG00000196196 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HRCT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HRCT1 | 646962 | 235496_at | -0.5022 | 0.1938 | |
| GSE26886 | HRCT1 | 646962 | 235496_at | 0.4380 | 0.0024 | |
| GSE45670 | HRCT1 | 646962 | 235496_at | -0.2125 | 0.0665 | |
| GSE53622 | HRCT1 | 646962 | 89542 | -1.7158 | 0.0000 | |
| GSE53624 | HRCT1 | 646962 | 89542 | -1.7634 | 0.0000 | |
| GSE63941 | HRCT1 | 646962 | 235496_at | -0.5697 | 0.1332 | |
| GSE77861 | HRCT1 | 646962 | 235496_at | -0.0258 | 0.8347 | |
| GSE97050 | HRCT1 | 646962 | A_23_P94434 | -0.4336 | 0.3208 | |
| SRP219564 | HRCT1 | 646962 | RNAseq | 0.0030 | 0.9965 | |
| TCGA | HRCT1 | 646962 | RNAseq | -1.4159 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by HRCT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HRCT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HRCT1 | 646962 | 3 | 12 | 15 | |
| GSE20123 | HRCT1 | 646962 | 3 | 12 | 15 | |
| GSE43470 | HRCT1 | 646962 | 3 | 10 | 30 | |
| GSE46452 | HRCT1 | 646962 | 6 | 15 | 38 | |
| GSE47630 | HRCT1 | 646962 | 1 | 20 | 19 | |
| GSE54993 | HRCT1 | 646962 | 6 | 0 | 64 | |
| GSE54994 | HRCT1 | 646962 | 5 | 12 | 36 | |
| GSE60625 | HRCT1 | 646962 | 0 | 0 | 11 | |
| GSE74703 | HRCT1 | 646962 | 2 | 7 | 27 | |
| GSE74704 | HRCT1 | 646962 | 0 | 10 | 10 | |
| TCGA | HRCT1 | 646962 | 17 | 44 | 35 |
Total number of gains: 46; Total number of losses: 142; Total Number of normals: 300.
Somatic mutations of HRCT1:
Generating mutation plots.
Highly correlated genes for HRCT1:
Showing top 20/227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HRCT1 | KLHL10 | 0.807584 | 4 | 0 | 4 |
| HRCT1 | SCN2B | 0.780354 | 3 | 0 | 3 |
| HRCT1 | FAM163B | 0.769666 | 3 | 0 | 3 |
| HRCT1 | PGPEP1 | 0.768268 | 3 | 0 | 3 |
| HRCT1 | GNAZ | 0.752014 | 3 | 0 | 3 |
| HRCT1 | IL2 | 0.734472 | 3 | 0 | 3 |
| HRCT1 | SP7 | 0.729214 | 3 | 0 | 3 |
| HRCT1 | TPO | 0.729188 | 3 | 0 | 3 |
| HRCT1 | MUC22 | 0.727296 | 3 | 0 | 3 |
| HRCT1 | PTGDS | 0.722551 | 3 | 0 | 3 |
| HRCT1 | BARHL2 | 0.718179 | 3 | 0 | 3 |
| HRCT1 | SYPL2 | 0.716179 | 3 | 0 | 3 |
| HRCT1 | DCD | 0.710151 | 4 | 0 | 4 |
| HRCT1 | SRPK3 | 0.707174 | 3 | 0 | 3 |
| HRCT1 | RNF222 | 0.705399 | 3 | 0 | 3 |
| HRCT1 | CSTL1 | 0.704758 | 4 | 0 | 4 |
| HRCT1 | PDE1C | 0.704633 | 3 | 0 | 3 |
| HRCT1 | HAAO | 0.703304 | 4 | 0 | 4 |
| HRCT1 | OTOF | 0.700439 | 5 | 0 | 5 |
| HRCT1 | TNXB | 0.699335 | 4 | 0 | 4 |
For details and further investigation, click here
