| Full name: coiled-coil domain containing 50 | Alias Symbol: Ymer | ||
| Type: protein-coding gene | Cytoband: 3q28 | ||
| Entrez ID: 152137 | HGNC ID: HGNC:18111 | Ensembl Gene: ENSG00000152492 | OMIM ID: 611051 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC50:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC50 | 152137 | 225331_at | 0.0623 | 0.9228 | |
| GSE26886 | CCDC50 | 152137 | 225331_at | 1.0175 | 0.0009 | |
| GSE45670 | CCDC50 | 152137 | 225331_at | 0.3018 | 0.2545 | |
| GSE53622 | CCDC50 | 152137 | 112484 | -2.5460 | 0.0000 | |
| GSE53624 | CCDC50 | 152137 | 112484 | -1.8566 | 0.0000 | |
| GSE63941 | CCDC50 | 152137 | 225331_at | -0.7686 | 0.2264 | |
| GSE77861 | CCDC50 | 152137 | 225331_at | 0.5532 | 0.2273 | |
| GSE97050 | CCDC50 | 152137 | A_24_P910733 | -1.8283 | 0.0867 | |
| SRP007169 | CCDC50 | 152137 | RNAseq | 0.9744 | 0.0050 | |
| SRP008496 | CCDC50 | 152137 | RNAseq | 1.1837 | 0.0000 | |
| SRP064894 | CCDC50 | 152137 | RNAseq | 0.1638 | 0.3479 | |
| SRP133303 | CCDC50 | 152137 | RNAseq | 0.3828 | 0.0346 | |
| SRP159526 | CCDC50 | 152137 | RNAseq | 0.1771 | 0.4245 | |
| SRP193095 | CCDC50 | 152137 | RNAseq | 0.5358 | 0.0003 | |
| SRP219564 | CCDC50 | 152137 | RNAseq | -0.2776 | 0.5207 | |
| TCGA | CCDC50 | 152137 | RNAseq | -0.1460 | 0.0269 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by CCDC50 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC50:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC50 | 152137 | 25 | 0 | 5 | |
| GSE20123 | CCDC50 | 152137 | 25 | 0 | 5 | |
| GSE43470 | CCDC50 | 152137 | 26 | 0 | 17 | |
| GSE46452 | CCDC50 | 152137 | 19 | 1 | 39 | |
| GSE47630 | CCDC50 | 152137 | 27 | 2 | 11 | |
| GSE54993 | CCDC50 | 152137 | 1 | 20 | 49 | |
| GSE54994 | CCDC50 | 152137 | 40 | 0 | 13 | |
| GSE60625 | CCDC50 | 152137 | 0 | 6 | 5 | |
| GSE74703 | CCDC50 | 152137 | 21 | 0 | 15 | |
| GSE74704 | CCDC50 | 152137 | 17 | 0 | 3 | |
| TCGA | CCDC50 | 152137 | 77 | 0 | 19 |
Total number of gains: 278; Total number of losses: 29; Total Number of normals: 181.
Somatic mutations of CCDC50:
Generating mutation plots.
Highly correlated genes for CCDC50:
Showing top 20/73 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC50 | IQCF1 | 0.847712 | 3 | 0 | 3 |
| CCDC50 | NCCRP1 | 0.819557 | 3 | 0 | 3 |
| CCDC50 | KRTAP20-1 | 0.815504 | 3 | 0 | 3 |
| CCDC50 | KRT83 | 0.798793 | 3 | 0 | 3 |
| CCDC50 | FAM163B | 0.779658 | 3 | 0 | 3 |
| CCDC50 | GPX6 | 0.777117 | 3 | 0 | 3 |
| CCDC50 | MYZAP | 0.762994 | 3 | 0 | 3 |
| CCDC50 | TMPRSS11A | 0.756936 | 3 | 0 | 3 |
| CCDC50 | KPRP | 0.751761 | 3 | 0 | 3 |
| CCDC50 | OR2Z1 | 0.748274 | 3 | 0 | 3 |
| CCDC50 | MUC22 | 0.746481 | 3 | 0 | 3 |
| CCDC50 | ARID5A | 0.744802 | 5 | 0 | 4 |
| CCDC50 | OTOP3 | 0.741463 | 3 | 0 | 3 |
| CCDC50 | MFSD2B | 0.706348 | 3 | 0 | 3 |
| CCDC50 | KCNA7 | 0.69958 | 3 | 0 | 3 |
| CCDC50 | PRSS1 | 0.693868 | 3 | 0 | 3 |
| CCDC50 | SLC4A3 | 0.692839 | 5 | 0 | 4 |
| CCDC50 | SFXN3 | 0.686697 | 6 | 0 | 6 |
| CCDC50 | OR5AS1 | 0.684188 | 3 | 0 | 3 |
| CCDC50 | SLC25A12 | 0.682399 | 3 | 0 | 3 |
For details and further investigation, click here
