| Full name: adaptor related protein complex 1 subunit gamma 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.2 | ||
| Entrez ID: 164 | HGNC ID: HGNC:555 | Ensembl Gene: ENSG00000166747 | OMIM ID: 603533 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of AP1G1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AP1G1 | 164 | 225771_at | 0.3009 | 0.5347 | |
| GSE20347 | AP1G1 | 164 | 203350_at | -0.3967 | 0.0010 | |
| GSE23400 | AP1G1 | 164 | 203350_at | -0.1571 | 0.0423 | |
| GSE26886 | AP1G1 | 164 | 225771_at | -1.0015 | 0.0000 | |
| GSE29001 | AP1G1 | 164 | 203350_at | -0.5804 | 0.0202 | |
| GSE38129 | AP1G1 | 164 | 203350_at | -0.0150 | 0.9533 | |
| GSE45670 | AP1G1 | 164 | 225771_at | -0.0286 | 0.8243 | |
| GSE53622 | AP1G1 | 164 | 19019 | -0.2602 | 0.0001 | |
| GSE53624 | AP1G1 | 164 | 19019 | -0.3702 | 0.0000 | |
| GSE63941 | AP1G1 | 164 | 225771_at | -0.2692 | 0.3615 | |
| GSE77861 | AP1G1 | 164 | 225771_at | -0.0413 | 0.8035 | |
| GSE97050 | AP1G1 | 164 | A_24_P381962 | 0.0667 | 0.7732 | |
| SRP007169 | AP1G1 | 164 | RNAseq | -0.5372 | 0.0812 | |
| SRP008496 | AP1G1 | 164 | RNAseq | -0.7836 | 0.0003 | |
| SRP064894 | AP1G1 | 164 | RNAseq | -0.7818 | 0.0001 | |
| SRP133303 | AP1G1 | 164 | RNAseq | -0.0110 | 0.9382 | |
| SRP159526 | AP1G1 | 164 | RNAseq | -0.4899 | 0.0102 | |
| SRP193095 | AP1G1 | 164 | RNAseq | -0.3403 | 0.0001 | |
| SRP219564 | AP1G1 | 164 | RNAseq | -0.5584 | 0.1151 | |
| TCGA | AP1G1 | 164 | RNAseq | -0.1248 | 0.0027 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AP1G1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AP1G1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AP1G1 | 164 | 4 | 0 | 26 | |
| GSE20123 | AP1G1 | 164 | 4 | 0 | 26 | |
| GSE43470 | AP1G1 | 164 | 2 | 8 | 33 | |
| GSE46452 | AP1G1 | 164 | 38 | 2 | 19 | |
| GSE47630 | AP1G1 | 164 | 11 | 8 | 21 | |
| GSE54993 | AP1G1 | 164 | 2 | 4 | 64 | |
| GSE54994 | AP1G1 | 164 | 8 | 10 | 35 | |
| GSE60625 | AP1G1 | 164 | 4 | 0 | 7 | |
| GSE74703 | AP1G1 | 164 | 2 | 5 | 29 | |
| GSE74704 | AP1G1 | 164 | 2 | 0 | 18 | |
| TCGA | AP1G1 | 164 | 28 | 12 | 56 |
Total number of gains: 105; Total number of losses: 49; Total Number of normals: 334.
Somatic mutations of AP1G1:
Generating mutation plots.
Highly correlated genes for AP1G1:
Showing top 20/905 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AP1G1 | MRPL30 | 0.80092 | 3 | 0 | 3 |
| AP1G1 | APOOL | 0.773324 | 3 | 0 | 3 |
| AP1G1 | NIPBL | 0.755683 | 3 | 0 | 3 |
| AP1G1 | TMEM54 | 0.741315 | 3 | 0 | 3 |
| AP1G1 | RAP2B | 0.73616 | 4 | 0 | 4 |
| AP1G1 | RSPRY1 | 0.733673 | 4 | 0 | 4 |
| AP1G1 | SRPRB | 0.730396 | 4 | 0 | 4 |
| AP1G1 | RNF24 | 0.727878 | 3 | 0 | 3 |
| AP1G1 | MAP4K5 | 0.725535 | 4 | 0 | 3 |
| AP1G1 | ENC1 | 0.724552 | 3 | 0 | 3 |
| AP1G1 | SLC50A1 | 0.723171 | 3 | 0 | 3 |
| AP1G1 | LACTB | 0.722505 | 4 | 0 | 3 |
| AP1G1 | CCNYL1 | 0.716806 | 4 | 0 | 4 |
| AP1G1 | JAK2 | 0.71457 | 4 | 0 | 3 |
| AP1G1 | WDR3 | 0.713936 | 3 | 0 | 3 |
| AP1G1 | EAF1 | 0.707627 | 4 | 0 | 3 |
| AP1G1 | TMEM208 | 0.707602 | 4 | 0 | 3 |
| AP1G1 | TBC1D23 | 0.707561 | 3 | 0 | 3 |
| AP1G1 | SENP8 | 0.696881 | 3 | 0 | 3 |
| AP1G1 | SCRN3 | 0.694363 | 4 | 0 | 3 |
For details and further investigation, click here
