| Full name: transmembrane protein 54 | Alias Symbol: CAC-1 | ||
| Type: protein-coding gene | Cytoband: 1p35.1 | ||
| Entrez ID: 113452 | HGNC ID: HGNC:24143 | Ensembl Gene: ENSG00000121900 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM54 | 113452 | 225536_at | 0.1502 | 0.8121 | |
| GSE26886 | TMEM54 | 113452 | 225536_at | -0.3977 | 0.0962 | |
| GSE45670 | TMEM54 | 113452 | 225536_at | 0.6277 | 0.0006 | |
| GSE53622 | TMEM54 | 113452 | 19384 | -0.4170 | 0.0000 | |
| GSE53624 | TMEM54 | 113452 | 19384 | -0.1536 | 0.0350 | |
| GSE63941 | TMEM54 | 113452 | 225536_at | 1.9081 | 0.0215 | |
| GSE77861 | TMEM54 | 113452 | 225536_at | 0.2143 | 0.5163 | |
| GSE97050 | TMEM54 | 113452 | A_33_P3230219 | 0.0983 | 0.7063 | |
| SRP007169 | TMEM54 | 113452 | RNAseq | -1.7222 | 0.0001 | |
| SRP008496 | TMEM54 | 113452 | RNAseq | -1.4971 | 0.0000 | |
| SRP064894 | TMEM54 | 113452 | RNAseq | 0.4512 | 0.2747 | |
| SRP133303 | TMEM54 | 113452 | RNAseq | 0.0157 | 0.9351 | |
| SRP159526 | TMEM54 | 113452 | RNAseq | -0.5712 | 0.0931 | |
| SRP193095 | TMEM54 | 113452 | RNAseq | -0.7666 | 0.0002 | |
| SRP219564 | TMEM54 | 113452 | RNAseq | -0.7164 | 0.0036 | |
| TCGA | TMEM54 | 113452 | RNAseq | 0.0514 | 0.4997 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by TMEM54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM54 | 113452 | 2 | 5 | 23 | |
| GSE20123 | TMEM54 | 113452 | 2 | 4 | 24 | |
| GSE43470 | TMEM54 | 113452 | 5 | 6 | 32 | |
| GSE46452 | TMEM54 | 113452 | 5 | 1 | 53 | |
| GSE47630 | TMEM54 | 113452 | 8 | 3 | 29 | |
| GSE54993 | TMEM54 | 113452 | 1 | 1 | 68 | |
| GSE54994 | TMEM54 | 113452 | 11 | 2 | 40 | |
| GSE60625 | TMEM54 | 113452 | 0 | 0 | 11 | |
| GSE74703 | TMEM54 | 113452 | 4 | 3 | 29 | |
| GSE74704 | TMEM54 | 113452 | 1 | 0 | 19 | |
| TCGA | TMEM54 | 113452 | 12 | 18 | 66 |
Total number of gains: 51; Total number of losses: 43; Total Number of normals: 394.
Somatic mutations of TMEM54:
Generating mutation plots.
Highly correlated genes for TMEM54:
Showing top 20/663 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM54 | HSPA9 | 0.790635 | 3 | 0 | 3 |
| TMEM54 | SAMD1 | 0.78978 | 3 | 0 | 3 |
| TMEM54 | E2F8 | 0.778224 | 3 | 0 | 3 |
| TMEM54 | FKBPL | 0.777185 | 3 | 0 | 3 |
| TMEM54 | NIPSNAP1 | 0.777016 | 4 | 0 | 3 |
| TMEM54 | ABCB6 | 0.775422 | 3 | 0 | 3 |
| TMEM54 | MRPL38 | 0.771832 | 3 | 0 | 3 |
| TMEM54 | TRAP1 | 0.760546 | 3 | 0 | 3 |
| TMEM54 | FBXO11 | 0.758378 | 3 | 0 | 3 |
| TMEM54 | GPD2 | 0.749558 | 3 | 0 | 3 |
| TMEM54 | UBA6 | 0.747811 | 3 | 0 | 3 |
| TMEM54 | PLEKHA7 | 0.74612 | 3 | 0 | 3 |
| TMEM54 | MCCC2 | 0.743961 | 3 | 0 | 3 |
| TMEM54 | PPP5C | 0.743459 | 3 | 0 | 3 |
| TMEM54 | GALNT3 | 0.743376 | 4 | 0 | 3 |
| TMEM54 | AP1G1 | 0.741315 | 3 | 0 | 3 |
| TMEM54 | NCAPH2 | 0.740176 | 4 | 0 | 4 |
| TMEM54 | PSMA5 | 0.736288 | 3 | 0 | 3 |
| TMEM54 | SEC61G | 0.735542 | 3 | 0 | 3 |
| TMEM54 | IL10RB | 0.734165 | 3 | 0 | 3 |
For details and further investigation, click here
