| Full name: solute carrier family 5 member 3 | Alias Symbol: SMIT|SMIT1 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 6526 | HGNC ID: HGNC:11038 | Ensembl Gene: ENSG00000198743 | OMIM ID: 600444 |
| Related drugs: PHLORIZIN... [more] | |||
Screen Evidence:
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Expression of SLC5A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC5A3 | 6526 | 213164_at | 1.0996 | 0.0355 | |
| GSE20347 | SLC5A3 | 6526 | 213164_at | 0.8941 | 0.0000 | |
| GSE23400 | SLC5A3 | 6526 | 213164_at | 0.8265 | 0.0000 | |
| GSE26886 | SLC5A3 | 6526 | 212944_at | 0.6290 | 0.1079 | |
| GSE29001 | SLC5A3 | 6526 | 212944_at | 0.9141 | 0.0438 | |
| GSE38129 | SLC5A3 | 6526 | 213164_at | 0.8600 | 0.0002 | |
| GSE45670 | SLC5A3 | 6526 | 213164_at | 0.8260 | 0.0112 | |
| GSE53622 | SLC5A3 | 6526 | 55031 | 0.3876 | 0.0000 | |
| GSE53624 | SLC5A3 | 6526 | 55031 | 0.7066 | 0.0000 | |
| GSE63941 | SLC5A3 | 6526 | 213164_at | 0.3251 | 0.6310 | |
| GSE77861 | SLC5A3 | 6526 | 213164_at | 0.6000 | 0.1319 | |
| GSE97050 | SLC5A3 | 6526 | A_33_P3277110 | 0.1788 | 0.4346 | |
| SRP007169 | SLC5A3 | 6526 | RNAseq | 1.4125 | 0.0001 | |
| SRP008496 | SLC5A3 | 6526 | RNAseq | 1.4074 | 0.0000 | |
| SRP064894 | SLC5A3 | 6526 | RNAseq | 1.0908 | 0.0009 | |
| SRP133303 | SLC5A3 | 6526 | RNAseq | 0.5874 | 0.0006 | |
| SRP159526 | SLC5A3 | 6526 | RNAseq | 0.2414 | 0.3414 | |
| SRP193095 | SLC5A3 | 6526 | RNAseq | 0.6359 | 0.0000 | |
| SRP219564 | SLC5A3 | 6526 | RNAseq | 0.6126 | 0.2278 | |
| TCGA | SLC5A3 | 6526 | RNAseq | 0.1730 | 0.0076 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SLC5A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC5A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC5A3 | 6526 | 2 | 7 | 21 | |
| GSE20123 | SLC5A3 | 6526 | 2 | 8 | 20 | |
| GSE43470 | SLC5A3 | 6526 | 1 | 11 | 31 | |
| GSE46452 | SLC5A3 | 6526 | 1 | 21 | 37 | |
| GSE47630 | SLC5A3 | 6526 | 6 | 17 | 17 | |
| GSE54993 | SLC5A3 | 6526 | 9 | 1 | 60 | |
| GSE54994 | SLC5A3 | 6526 | 1 | 9 | 43 | |
| GSE60625 | SLC5A3 | 6526 | 0 | 0 | 11 | |
| GSE74703 | SLC5A3 | 6526 | 1 | 8 | 27 | |
| GSE74704 | SLC5A3 | 6526 | 1 | 4 | 15 | |
| TCGA | SLC5A3 | 6526 | 8 | 37 | 51 |
Total number of gains: 32; Total number of losses: 123; Total Number of normals: 333.
Somatic mutations of SLC5A3:
Generating mutation plots.
Highly correlated genes for SLC5A3:
Showing top 20/1329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC5A3 | CMTM4 | 0.847672 | 3 | 0 | 3 |
| SLC5A3 | CBFA2T2 | 0.836808 | 3 | 0 | 3 |
| SLC5A3 | POU2F1 | 0.784853 | 3 | 0 | 3 |
| SLC5A3 | RRM2B | 0.770864 | 3 | 0 | 3 |
| SLC5A3 | SAP30L | 0.752801 | 3 | 0 | 3 |
| SLC5A3 | MRPL50 | 0.740003 | 3 | 0 | 3 |
| SLC5A3 | PIAS4 | 0.732225 | 4 | 0 | 3 |
| SLC5A3 | NAPEPLD | 0.725614 | 4 | 0 | 3 |
| SLC5A3 | TNRC18 | 0.724206 | 3 | 0 | 3 |
| SLC5A3 | TIGD1 | 0.722634 | 3 | 0 | 3 |
| SLC5A3 | HS6ST1 | 0.713953 | 3 | 0 | 3 |
| SLC5A3 | CCDC127 | 0.70726 | 3 | 0 | 3 |
| SLC5A3 | ZNF267 | 0.70467 | 3 | 0 | 3 |
| SLC5A3 | NCAPG | 0.704535 | 9 | 0 | 8 |
| SLC5A3 | MSTO1 | 0.703676 | 4 | 0 | 4 |
| SLC5A3 | BBS7 | 0.699176 | 3 | 0 | 3 |
| SLC5A3 | YWHAG | 0.697594 | 5 | 0 | 4 |
| SLC5A3 | IFRD2 | 0.692972 | 4 | 0 | 3 |
| SLC5A3 | ZNF451 | 0.688461 | 4 | 0 | 3 |
| SLC5A3 | MTERF3 | 0.688075 | 8 | 0 | 8 |
For details and further investigation, click here
