| Full name: seizure related 6 homolog like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q12.1 | ||
| Entrez ID: 23544 | HGNC ID: HGNC:10763 | Ensembl Gene: ENSG00000100095 | OMIM ID: 607021 |
| Drug and gene relationship at DGIdb | |||
Expression of SEZ6L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEZ6L | 23544 | 207873_x_at | -0.2659 | 0.2555 | |
| GSE20347 | SEZ6L | 23544 | 207873_x_at | -0.0099 | 0.9368 | |
| GSE23400 | SEZ6L | 23544 | 207873_x_at | -0.2300 | 0.0000 | |
| GSE26886 | SEZ6L | 23544 | 211894_x_at | 0.0105 | 0.9384 | |
| GSE29001 | SEZ6L | 23544 | 211894_x_at | -0.2466 | 0.0475 | |
| GSE38129 | SEZ6L | 23544 | 207873_x_at | -0.1266 | 0.1122 | |
| GSE45670 | SEZ6L | 23544 | 207873_x_at | -0.0034 | 0.9714 | |
| GSE53622 | SEZ6L | 23544 | 25191 | -0.8334 | 0.0006 | |
| GSE53624 | SEZ6L | 23544 | 25191 | -0.4363 | 0.0026 | |
| GSE63941 | SEZ6L | 23544 | 207873_x_at | -0.0433 | 0.8490 | |
| GSE77861 | SEZ6L | 23544 | 207873_x_at | -0.0318 | 0.7811 | |
| GSE97050 | SEZ6L | 23544 | A_23_P80242 | -0.0031 | 0.9898 | |
| TCGA | SEZ6L | 23544 | RNAseq | -1.8348 | 0.0381 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SEZ6L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEZ6L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEZ6L | 23544 | 3 | 6 | 21 | |
| GSE20123 | SEZ6L | 23544 | 3 | 5 | 22 | |
| GSE43470 | SEZ6L | 23544 | 3 | 7 | 33 | |
| GSE46452 | SEZ6L | 23544 | 31 | 1 | 27 | |
| GSE47630 | SEZ6L | 23544 | 8 | 5 | 27 | |
| GSE54993 | SEZ6L | 23544 | 3 | 6 | 61 | |
| GSE54994 | SEZ6L | 23544 | 11 | 8 | 34 | |
| GSE60625 | SEZ6L | 23544 | 5 | 0 | 6 | |
| GSE74703 | SEZ6L | 23544 | 3 | 6 | 27 | |
| GSE74704 | SEZ6L | 23544 | 0 | 2 | 18 | |
| TCGA | SEZ6L | 23544 | 26 | 14 | 56 |
Total number of gains: 96; Total number of losses: 60; Total Number of normals: 332.
Somatic mutations of SEZ6L:
Generating mutation plots.
Highly correlated genes for SEZ6L:
Showing top 20/735 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEZ6L | FEV | 0.715334 | 4 | 0 | 4 |
| SEZ6L | SLC5A4 | 0.712754 | 4 | 0 | 4 |
| SEZ6L | G6PC2 | 0.693751 | 5 | 0 | 5 |
| SEZ6L | DDX4 | 0.6934 | 3 | 0 | 3 |
| SEZ6L | NXPE4 | 0.691753 | 4 | 0 | 4 |
| SEZ6L | G6PC | 0.686346 | 3 | 0 | 3 |
| SEZ6L | FSHR | 0.682269 | 4 | 0 | 4 |
| SEZ6L | CA7 | 0.679827 | 4 | 0 | 4 |
| SEZ6L | HTR4 | 0.679161 | 4 | 0 | 4 |
| SEZ6L | SLC5A7 | 0.677971 | 4 | 0 | 4 |
| SEZ6L | HBZ | 0.676047 | 4 | 0 | 4 |
| SEZ6L | SLC6A5 | 0.670524 | 4 | 0 | 3 |
| SEZ6L | PARD6B | 0.670379 | 3 | 0 | 3 |
| SEZ6L | CSN2 | 0.669605 | 4 | 0 | 4 |
| SEZ6L | ART1 | 0.669267 | 5 | 0 | 5 |
| SEZ6L | EPOR | 0.667218 | 6 | 0 | 6 |
| SEZ6L | CA5A | 0.664383 | 5 | 0 | 5 |
| SEZ6L | TSSK2 | 0.664182 | 4 | 0 | 3 |
| SEZ6L | NCR2 | 0.662634 | 4 | 0 | 4 |
| SEZ6L | SHBG | 0.660677 | 5 | 0 | 5 |
For details and further investigation, click here
