| Full name: serine/threonine kinase receptor associated protein | Alias Symbol: UNRIP|pt-wd|MAWD | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 11171 | HGNC ID: HGNC:30796 | Ensembl Gene: ENSG00000023734 | OMIM ID: 605986 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of STRAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STRAP | 11171 | 200870_at | 0.2260 | 0.5548 | |
| GSE20347 | STRAP | 11171 | 200870_at | 0.3513 | 0.0221 | |
| GSE23400 | STRAP | 11171 | 200870_at | 0.4241 | 0.0000 | |
| GSE26886 | STRAP | 11171 | 200870_at | 0.2249 | 0.2861 | |
| GSE29001 | STRAP | 11171 | 200870_at | 0.3563 | 0.1222 | |
| GSE38129 | STRAP | 11171 | 200870_at | 0.3597 | 0.0034 | |
| GSE45670 | STRAP | 11171 | 200870_at | 0.2482 | 0.0934 | |
| GSE53622 | STRAP | 11171 | 38288 | 0.2773 | 0.0000 | |
| GSE53624 | STRAP | 11171 | 38288 | 0.5468 | 0.0000 | |
| GSE63941 | STRAP | 11171 | 200870_at | 0.1434 | 0.6967 | |
| GSE77861 | STRAP | 11171 | 200870_at | 0.5182 | 0.0306 | |
| GSE97050 | STRAP | 11171 | A_23_P13852 | -0.0261 | 0.9120 | |
| SRP007169 | STRAP | 11171 | RNAseq | 0.6617 | 0.0681 | |
| SRP008496 | STRAP | 11171 | RNAseq | 0.9969 | 0.0002 | |
| SRP064894 | STRAP | 11171 | RNAseq | 0.0219 | 0.8670 | |
| SRP133303 | STRAP | 11171 | RNAseq | 0.6969 | 0.0000 | |
| SRP159526 | STRAP | 11171 | RNAseq | 0.4082 | 0.0231 | |
| SRP193095 | STRAP | 11171 | RNAseq | 0.0457 | 0.6969 | |
| SRP219564 | STRAP | 11171 | RNAseq | 0.1461 | 0.6387 | |
| TCGA | STRAP | 11171 | RNAseq | 0.0624 | 0.1611 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STRAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STRAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRAP | 11171 | 6 | 2 | 22 | |
| GSE20123 | STRAP | 11171 | 6 | 2 | 22 | |
| GSE43470 | STRAP | 11171 | 9 | 4 | 30 | |
| GSE46452 | STRAP | 11171 | 10 | 1 | 48 | |
| GSE47630 | STRAP | 11171 | 14 | 1 | 25 | |
| GSE54993 | STRAP | 11171 | 1 | 9 | 60 | |
| GSE54994 | STRAP | 11171 | 11 | 2 | 40 | |
| GSE60625 | STRAP | 11171 | 0 | 1 | 10 | |
| GSE74703 | STRAP | 11171 | 9 | 3 | 24 | |
| GSE74704 | STRAP | 11171 | 4 | 1 | 15 | |
| TCGA | STRAP | 11171 | 41 | 5 | 50 |
Total number of gains: 111; Total number of losses: 31; Total Number of normals: 346.
Somatic mutations of STRAP:
Generating mutation plots.
Highly correlated genes for STRAP:
Showing top 20/1230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRAP | SETX | 0.793084 | 3 | 0 | 3 |
| STRAP | WBP11 | 0.780676 | 13 | 0 | 12 |
| STRAP | M6PR | 0.75434 | 8 | 0 | 8 |
| STRAP | ERLEC1 | 0.735563 | 4 | 0 | 4 |
| STRAP | CDC42SE2 | 0.733012 | 3 | 0 | 3 |
| STRAP | CYB5B | 0.73082 | 3 | 0 | 3 |
| STRAP | EMG1 | 0.729967 | 10 | 0 | 10 |
| STRAP | FAM118B | 0.729211 | 4 | 0 | 4 |
| STRAP | ANKRD40 | 0.726362 | 3 | 0 | 3 |
| STRAP | SMARCE1 | 0.725744 | 3 | 0 | 3 |
| STRAP | ZNF260 | 0.718999 | 3 | 0 | 3 |
| STRAP | SMU1 | 0.712847 | 3 | 0 | 3 |
| STRAP | DSE | 0.711978 | 3 | 0 | 3 |
| STRAP | LRP5L | 0.706695 | 3 | 0 | 3 |
| STRAP | UQCR10 | 0.699896 | 3 | 0 | 3 |
| STRAP | PYROXD1 | 0.697458 | 3 | 0 | 3 |
| STRAP | CERK | 0.693789 | 4 | 0 | 3 |
| STRAP | MLF2 | 0.693449 | 10 | 0 | 10 |
| STRAP | GAPDH | 0.692861 | 8 | 0 | 8 |
| STRAP | GOLT1B | 0.692087 | 13 | 0 | 12 |
For details and further investigation, click here
