| Full name: YTH N6-methyladenosine RNA binding protein 3 | Alias Symbol: FLJ31657 | ||
| Type: protein-coding gene | Cytoband: 8q12.3 | ||
| Entrez ID: 253943 | HGNC ID: HGNC:26465 | Ensembl Gene: ENSG00000185728 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of YTHDF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YTHDF3 | 253943 | 221749_at | 0.2940 | 0.4095 | |
| GSE20347 | YTHDF3 | 253943 | 221749_at | 0.2242 | 0.1408 | |
| GSE23400 | YTHDF3 | 253943 | 221749_at | 0.2476 | 0.0014 | |
| GSE26886 | YTHDF3 | 253943 | 221749_at | -0.1119 | 0.4706 | |
| GSE29001 | YTHDF3 | 253943 | 221749_at | 0.1665 | 0.4191 | |
| GSE38129 | YTHDF3 | 253943 | 221749_at | 0.0545 | 0.6955 | |
| GSE45670 | YTHDF3 | 253943 | 221749_at | 0.0554 | 0.5799 | |
| GSE53622 | YTHDF3 | 253943 | 7339 | 0.0691 | 0.1697 | |
| GSE53624 | YTHDF3 | 253943 | 7339 | -0.1256 | 0.0049 | |
| GSE63941 | YTHDF3 | 253943 | 221749_at | -0.9659 | 0.0091 | |
| GSE77861 | YTHDF3 | 253943 | 221749_at | -0.0154 | 0.9685 | |
| GSE97050 | YTHDF3 | 253943 | A_33_P3264419 | -0.2829 | 0.4023 | |
| SRP007169 | YTHDF3 | 253943 | RNAseq | -0.5908 | 0.0742 | |
| SRP008496 | YTHDF3 | 253943 | RNAseq | -0.4766 | 0.0118 | |
| SRP064894 | YTHDF3 | 253943 | RNAseq | 0.2870 | 0.1081 | |
| SRP133303 | YTHDF3 | 253943 | RNAseq | 0.2337 | 0.0336 | |
| SRP159526 | YTHDF3 | 253943 | RNAseq | -0.0401 | 0.7882 | |
| SRP193095 | YTHDF3 | 253943 | RNAseq | -0.1646 | 0.0857 | |
| SRP219564 | YTHDF3 | 253943 | RNAseq | 0.0812 | 0.7577 | |
| TCGA | YTHDF3 | 253943 | RNAseq | -0.0709 | 0.0981 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by YTHDF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YTHDF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YTHDF3 | 253943 | 13 | 1 | 16 | |
| GSE20123 | YTHDF3 | 253943 | 13 | 1 | 16 | |
| GSE43470 | YTHDF3 | 253943 | 15 | 3 | 25 | |
| GSE46452 | YTHDF3 | 253943 | 21 | 1 | 37 | |
| GSE47630 | YTHDF3 | 253943 | 23 | 1 | 16 | |
| GSE54993 | YTHDF3 | 253943 | 1 | 18 | 51 | |
| GSE54994 | YTHDF3 | 253943 | 30 | 0 | 23 | |
| GSE60625 | YTHDF3 | 253943 | 0 | 4 | 7 | |
| GSE74703 | YTHDF3 | 253943 | 13 | 2 | 21 | |
| GSE74704 | YTHDF3 | 253943 | 9 | 0 | 11 | |
| TCGA | YTHDF3 | 253943 | 46 | 6 | 44 |
Total number of gains: 184; Total number of losses: 37; Total Number of normals: 267.
Somatic mutations of YTHDF3:
Generating mutation plots.
Highly correlated genes for YTHDF3:
Showing top 20/332 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YTHDF3 | WTIP | 0.770374 | 3 | 0 | 3 |
| YTHDF3 | ZNF441 | 0.770304 | 3 | 0 | 3 |
| YTHDF3 | ZNF451 | 0.758091 | 3 | 0 | 3 |
| YTHDF3 | TOMM40L | 0.746687 | 3 | 0 | 3 |
| YTHDF3 | MRAS | 0.746458 | 3 | 0 | 3 |
| YTHDF3 | IGIP | 0.745259 | 3 | 0 | 3 |
| YTHDF3 | RBPJ | 0.741702 | 4 | 0 | 4 |
| YTHDF3 | CHIC1 | 0.738009 | 3 | 0 | 3 |
| YTHDF3 | TTC14 | 0.737419 | 3 | 0 | 3 |
| YTHDF3 | EED | 0.735367 | 3 | 0 | 3 |
| YTHDF3 | VPS36 | 0.732709 | 3 | 0 | 3 |
| YTHDF3 | SNRNP48 | 0.731445 | 3 | 0 | 3 |
| YTHDF3 | ANAPC4 | 0.729829 | 3 | 0 | 3 |
| YTHDF3 | ZNF71 | 0.725425 | 3 | 0 | 3 |
| YTHDF3 | GK5 | 0.719237 | 3 | 0 | 3 |
| YTHDF3 | DPY19L3 | 0.714458 | 3 | 0 | 3 |
| YTHDF3 | SCRN3 | 0.713745 | 3 | 0 | 3 |
| YTHDF3 | DSTYK | 0.710013 | 3 | 0 | 3 |
| YTHDF3 | NOP58 | 0.709337 | 3 | 0 | 3 |
| YTHDF3 | GLCCI1 | 0.708977 | 3 | 0 | 3 |
For details and further investigation, click here
