| Full name: MORC family CW-type zinc finger 2 | Alias Symbol: ZCW3|KIAA0852|AC004542.C22.1 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 22880 | HGNC ID: HGNC:23573 | Ensembl Gene: ENSG00000133422 | OMIM ID: 616661 |
| Drug and gene relationship at DGIdb | |||
Expression of MORC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MORC2 | 22880 | 203956_at | 1.0685 | 0.0815 | |
| GSE20347 | MORC2 | 22880 | 203956_at | 1.0640 | 0.0000 | |
| GSE23400 | MORC2 | 22880 | 203956_at | 0.7286 | 0.0000 | |
| GSE26886 | MORC2 | 22880 | 203956_at | 2.2720 | 0.0000 | |
| GSE29001 | MORC2 | 22880 | 203956_at | 0.9348 | 0.0004 | |
| GSE38129 | MORC2 | 22880 | 203956_at | 1.0285 | 0.0000 | |
| GSE45670 | MORC2 | 22880 | 203956_at | 0.8596 | 0.0000 | |
| GSE53622 | MORC2 | 22880 | 66187 | 0.8442 | 0.0000 | |
| GSE53624 | MORC2 | 22880 | 66187 | 1.0361 | 0.0000 | |
| GSE63941 | MORC2 | 22880 | 203956_at | -0.4349 | 0.2331 | |
| GSE77861 | MORC2 | 22880 | 203956_at | 1.0414 | 0.0003 | |
| GSE97050 | MORC2 | 22880 | A_24_P100234 | 0.5785 | 0.1108 | |
| SRP007169 | MORC2 | 22880 | RNAseq | 2.1039 | 0.0000 | |
| SRP008496 | MORC2 | 22880 | RNAseq | 1.7111 | 0.0000 | |
| SRP064894 | MORC2 | 22880 | RNAseq | 0.9610 | 0.0000 | |
| SRP133303 | MORC2 | 22880 | RNAseq | 0.8921 | 0.0000 | |
| SRP159526 | MORC2 | 22880 | RNAseq | 1.0660 | 0.0001 | |
| SRP193095 | MORC2 | 22880 | RNAseq | 1.0281 | 0.0000 | |
| SRP219564 | MORC2 | 22880 | RNAseq | 0.8041 | 0.0162 | |
| TCGA | MORC2 | 22880 | RNAseq | 0.2300 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by MORC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MORC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MORC2 | 22880 | 4 | 5 | 21 | |
| GSE20123 | MORC2 | 22880 | 4 | 4 | 22 | |
| GSE43470 | MORC2 | 22880 | 4 | 5 | 34 | |
| GSE46452 | MORC2 | 22880 | 31 | 1 | 27 | |
| GSE47630 | MORC2 | 22880 | 8 | 5 | 27 | |
| GSE54993 | MORC2 | 22880 | 3 | 6 | 61 | |
| GSE54994 | MORC2 | 22880 | 12 | 7 | 34 | |
| GSE60625 | MORC2 | 22880 | 5 | 0 | 6 | |
| GSE74703 | MORC2 | 22880 | 4 | 5 | 27 | |
| GSE74704 | MORC2 | 22880 | 1 | 1 | 18 | |
| TCGA | MORC2 | 22880 | 28 | 15 | 53 |
Total number of gains: 104; Total number of losses: 54; Total Number of normals: 330.
Somatic mutations of MORC2:
Generating mutation plots.
Highly correlated genes for MORC2:
Showing top 20/2103 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MORC2 | XAB2 | 0.864684 | 3 | 0 | 3 |
| MORC2 | SLC39A3 | 0.836103 | 4 | 0 | 4 |
| MORC2 | U2SURP | 0.82668 | 9 | 0 | 9 |
| MORC2 | AURKAIP1 | 0.820751 | 3 | 0 | 3 |
| MORC2 | ALKBH6 | 0.817535 | 5 | 0 | 5 |
| MORC2 | ZNF579 | 0.815229 | 3 | 0 | 3 |
| MORC2 | SRRT | 0.807145 | 10 | 0 | 10 |
| MORC2 | LRRC58 | 0.805905 | 5 | 0 | 5 |
| MORC2 | PLXNA1 | 0.782078 | 11 | 0 | 10 |
| MORC2 | MTERF3 | 0.775155 | 8 | 0 | 8 |
| MORC2 | DNAJC2 | 0.771855 | 11 | 0 | 11 |
| MORC2 | RASEF | 0.766 | 4 | 0 | 4 |
| MORC2 | GNG10 | 0.764918 | 3 | 0 | 3 |
| MORC2 | CMSS1 | 0.763981 | 6 | 0 | 6 |
| MORC2 | RIOK1 | 0.760537 | 7 | 0 | 7 |
| MORC2 | FAM89A | 0.75785 | 3 | 0 | 3 |
| MORC2 | ZCCHC7 | 0.756329 | 3 | 0 | 3 |
| MORC2 | HGS | 0.755243 | 3 | 0 | 3 |
| MORC2 | C15orf61 | 0.751757 | 3 | 0 | 3 |
| MORC2 | ZNF628 | 0.750202 | 4 | 0 | 3 |
For details and further investigation, click here
