| Full name: RNA binding motif protein 15 | Alias Symbol: OTT|OTT1 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 64783 | HGNC ID: HGNC:14959 | Ensembl Gene: ENSG00000162775 | OMIM ID: 606077 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBM15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM15 | 64783 | 219286_s_at | 0.6487 | 0.0466 | |
| GSE20347 | RBM15 | 64783 | 219286_s_at | 0.4373 | 0.0005 | |
| GSE23400 | RBM15 | 64783 | 219286_s_at | 0.4419 | 0.0000 | |
| GSE26886 | RBM15 | 64783 | 219286_s_at | 0.9238 | 0.0000 | |
| GSE29001 | RBM15 | 64783 | 219286_s_at | 0.7112 | 0.0013 | |
| GSE38129 | RBM15 | 64783 | 219286_s_at | 0.3787 | 0.0001 | |
| GSE45670 | RBM15 | 64783 | 219286_s_at | 0.2008 | 0.0879 | |
| GSE53622 | RBM15 | 64783 | 117589 | 0.0277 | 0.7309 | |
| GSE53624 | RBM15 | 64783 | 117589 | -0.8587 | 0.0000 | |
| GSE63941 | RBM15 | 64783 | 219286_s_at | 0.1692 | 0.6776 | |
| GSE77861 | RBM15 | 64783 | 219286_s_at | 0.3690 | 0.0458 | |
| GSE97050 | RBM15 | 64783 | A_23_P34877 | 0.2856 | 0.5027 | |
| SRP007169 | RBM15 | 64783 | RNAseq | 1.1733 | 0.0069 | |
| SRP008496 | RBM15 | 64783 | RNAseq | 1.0610 | 0.0015 | |
| SRP064894 | RBM15 | 64783 | RNAseq | 0.5532 | 0.0006 | |
| SRP133303 | RBM15 | 64783 | RNAseq | 0.3777 | 0.0149 | |
| SRP159526 | RBM15 | 64783 | RNAseq | 0.0232 | 0.9292 | |
| SRP193095 | RBM15 | 64783 | RNAseq | 0.3052 | 0.0000 | |
| SRP219564 | RBM15 | 64783 | RNAseq | 0.5189 | 0.1827 | |
| TCGA | RBM15 | 64783 | RNAseq | 0.0208 | 0.7190 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RBM15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM15 | 64783 | 0 | 11 | 19 | |
| GSE20123 | RBM15 | 64783 | 0 | 11 | 19 | |
| GSE43470 | RBM15 | 64783 | 0 | 8 | 35 | |
| GSE46452 | RBM15 | 64783 | 2 | 1 | 56 | |
| GSE47630 | RBM15 | 64783 | 9 | 5 | 26 | |
| GSE54993 | RBM15 | 64783 | 0 | 1 | 69 | |
| GSE54994 | RBM15 | 64783 | 7 | 4 | 42 | |
| GSE60625 | RBM15 | 64783 | 0 | 0 | 11 | |
| GSE74703 | RBM15 | 64783 | 0 | 7 | 29 | |
| GSE74704 | RBM15 | 64783 | 0 | 7 | 13 | |
| TCGA | RBM15 | 64783 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 81; Total Number of normals: 380.
Somatic mutations of RBM15:
Generating mutation plots.
Highly correlated genes for RBM15:
Showing top 20/628 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM15 | ZNF668 | 0.76352 | 3 | 0 | 3 |
| RBM15 | ACACA | 0.754864 | 3 | 0 | 3 |
| RBM15 | POLR1B | 0.75212 | 3 | 0 | 3 |
| RBM15 | TRIM59 | 0.746118 | 3 | 0 | 3 |
| RBM15 | CPT1A | 0.745191 | 3 | 0 | 3 |
| RBM15 | ESCO1 | 0.74104 | 4 | 0 | 3 |
| RBM15 | INO80E | 0.736271 | 3 | 0 | 3 |
| RBM15 | RAVER1 | 0.729778 | 4 | 0 | 3 |
| RBM15 | SNRNP48 | 0.727471 | 3 | 0 | 3 |
| RBM15 | WDR5 | 0.724498 | 4 | 0 | 4 |
| RBM15 | AURKAIP1 | 0.724221 | 4 | 0 | 3 |
| RBM15 | LTV1 | 0.712489 | 3 | 0 | 3 |
| RBM15 | RPS21 | 0.711841 | 3 | 0 | 3 |
| RBM15 | SGTB | 0.709837 | 3 | 0 | 3 |
| RBM15 | SFR1 | 0.705559 | 4 | 0 | 3 |
| RBM15 | INPP5B | 0.702053 | 4 | 0 | 4 |
| RBM15 | TERF2 | 0.699448 | 3 | 0 | 3 |
| RBM15 | PET117 | 0.692973 | 4 | 0 | 4 |
| RBM15 | SNRPG | 0.692856 | 10 | 0 | 10 |
| RBM15 | CDCA2 | 0.692679 | 5 | 0 | 5 |
For details and further investigation, click here
