FRMD3

 

Full name: FERM domain containing 3 Alias Symbol: EPB41L4O|MGC20553
Type: protein-coding gene Cytoband: 9q21.32
Entrez ID: 257019 HGNC ID: HGNC:24125 Ensembl Gene: ENSG00000172159 OMIM ID: 607619
Drug and gene relationship at DGIdb

 

Expression of FRMD3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FRMD3 257019 229893_at -0.6095 0.3742
GSE26886 FRMD3 257019 229893_at 0.0976 0.5289
GSE45670 FRMD3 257019 229893_at -1.2250 0.0001
GSE53622 FRMD3 257019 72197 -1.7283 0.0000
GSE53624 FRMD3 257019 10492 -1.1912 0.0000
GSE63941 FRMD3 257019 229893_at 0.2589 0.5464
GSE77861 FRMD3 257019 229893_at 0.1937 0.1220
GSE97050 FRMD3 257019 A_23_P135132 -0.7812 0.1439
SRP064894 FRMD3 257019 RNAseq 0.2871 0.4566
SRP133303 FRMD3 257019 RNAseq -0.6184 0.0447
SRP159526 FRMD3 257019 RNAseq 0.5551 0.3658
SRP193095 FRMD3 257019 RNAseq -0.5495 0.1494
SRP219564 FRMD3 257019 RNAseq 0.3045 0.6814
TCGA FRMD3 257019 RNAseq -1.8818 0.0000

Upregulated datasets: 0; Downregulated datasets: 4.  

 

Survival by FRMD3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FRMD3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FRMD3 257019 5 10 15
GSE20123 FRMD3 257019 5 10 15
GSE43470 FRMD3 257019 6 3 34
GSE46452 FRMD3 257019 6 14 39
GSE47630 FRMD3 257019 1 18 21
GSE54993 FRMD3 257019 4 2 64
GSE54994 FRMD3 257019 5 12 36
GSE60625 FRMD3 257019 0 0 11
GSE74703 FRMD3 257019 5 3 28
GSE74704 FRMD3 257019 3 7 10
TCGA FRMD3 257019 20 29 47

Total number of gains: 60; Total number of losses: 108; Total Number of normals: 320.  

 

Somatic mutations of FRMD3:

 

Generating mutation plots.

 

Highly correlated genes for FRMD3:

 

Showing top 20/860 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FRMD3ZDHHC170.862651303
FRMD3KIAA07530.853554303
FRMD3CYP2U10.808399505
FRMD3C1QTNF70.804841505
FRMD3BHMT20.804288505
FRMD3UBXN100.800486404
FRMD3XKR40.80008505
FRMD3MAN1C10.796276505
FRMD3JAM20.796078505
FRMD3CYSLTR10.795679505
FRMD3CBX70.792763505
FRMD3ANGPTL10.791889505
FRMD3CLEC3B0.786662303
FRMD3SORCS10.785994404
FRMD3TNFSF120.783516303
FRMD3CELF20.782239505
FRMD3KCNT20.779527606
FRMD3EZH10.775489404
FRMD3ANK20.773575504
FRMD3PDK40.772069404

For details and further investigation, click here