| Full name: sorting nexin 4 | Alias Symbol: ATG24B | ||
| Type: protein-coding gene | Cytoband: 3q21.2 | ||
| Entrez ID: 8723 | HGNC ID: HGNC:11175 | Ensembl Gene: ENSG00000114520 | OMIM ID: 605931 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX4 | 8723 | 212652_s_at | 0.3064 | 0.4573 | |
| GSE20347 | SNX4 | 8723 | 212652_s_at | 0.4113 | 0.0040 | |
| GSE23400 | SNX4 | 8723 | 212652_s_at | 0.4734 | 0.0000 | |
| GSE26886 | SNX4 | 8723 | 212652_s_at | -0.6981 | 0.0011 | |
| GSE29001 | SNX4 | 8723 | 212652_s_at | 0.5026 | 0.0718 | |
| GSE38129 | SNX4 | 8723 | 212652_s_at | 0.3354 | 0.0079 | |
| GSE45670 | SNX4 | 8723 | 212652_s_at | 0.0654 | 0.6719 | |
| GSE53622 | SNX4 | 8723 | 118184 | 0.0867 | 0.2764 | |
| GSE53624 | SNX4 | 8723 | 118184 | 0.0463 | 0.5847 | |
| GSE63941 | SNX4 | 8723 | 212652_s_at | -0.1145 | 0.7684 | |
| GSE77861 | SNX4 | 8723 | 212652_s_at | 0.0550 | 0.9003 | |
| GSE97050 | SNX4 | 8723 | A_23_P72568 | -0.0780 | 0.8055 | |
| SRP007169 | SNX4 | 8723 | RNAseq | 0.0894 | 0.7892 | |
| SRP008496 | SNX4 | 8723 | RNAseq | 0.6408 | 0.0131 | |
| SRP064894 | SNX4 | 8723 | RNAseq | 0.0791 | 0.6974 | |
| SRP133303 | SNX4 | 8723 | RNAseq | 0.4176 | 0.0101 | |
| SRP159526 | SNX4 | 8723 | RNAseq | 0.2430 | 0.2638 | |
| SRP193095 | SNX4 | 8723 | RNAseq | -0.1301 | 0.3060 | |
| SRP219564 | SNX4 | 8723 | RNAseq | -0.1200 | 0.6054 | |
| TCGA | SNX4 | 8723 | RNAseq | -0.0510 | 0.3196 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNX4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX4 | 8723 | 17 | 0 | 13 | |
| GSE20123 | SNX4 | 8723 | 17 | 0 | 13 | |
| GSE43470 | SNX4 | 8723 | 20 | 0 | 23 | |
| GSE46452 | SNX4 | 8723 | 14 | 5 | 40 | |
| GSE47630 | SNX4 | 8723 | 17 | 4 | 19 | |
| GSE54993 | SNX4 | 8723 | 2 | 7 | 61 | |
| GSE54994 | SNX4 | 8723 | 31 | 3 | 19 | |
| GSE60625 | SNX4 | 8723 | 0 | 6 | 5 | |
| GSE74703 | SNX4 | 8723 | 17 | 0 | 19 | |
| GSE74704 | SNX4 | 8723 | 13 | 0 | 7 | |
| TCGA | SNX4 | 8723 | 55 | 6 | 35 |
Total number of gains: 203; Total number of losses: 31; Total Number of normals: 254.
Somatic mutations of SNX4:
Generating mutation plots.
Highly correlated genes for SNX4:
Showing top 20/681 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX4 | PSEN1 | 0.789258 | 3 | 0 | 3 |
| SNX4 | SLC30A9 | 0.782342 | 3 | 0 | 3 |
| SNX4 | TRAPPC8 | 0.773304 | 3 | 0 | 3 |
| SNX4 | SLC35C2 | 0.768769 | 3 | 0 | 3 |
| SNX4 | RCHY1 | 0.766056 | 4 | 0 | 4 |
| SNX4 | SPPL3 | 0.76274 | 3 | 0 | 3 |
| SNX4 | HEATR5A | 0.758902 | 3 | 0 | 3 |
| SNX4 | PSPC1 | 0.737714 | 3 | 0 | 3 |
| SNX4 | TMEM41B | 0.735028 | 3 | 0 | 3 |
| SNX4 | SLC37A3 | 0.730174 | 3 | 0 | 3 |
| SNX4 | ACSS2 | 0.730036 | 3 | 0 | 3 |
| SNX4 | CYLD | 0.72994 | 3 | 0 | 3 |
| SNX4 | ATG2B | 0.723617 | 3 | 0 | 3 |
| SNX4 | NEK4 | 0.721522 | 4 | 0 | 3 |
| SNX4 | FBXO28 | 0.721406 | 3 | 0 | 3 |
| SNX4 | NAA25 | 0.716215 | 4 | 0 | 3 |
| SNX4 | AKAP11 | 0.715338 | 3 | 0 | 3 |
| SNX4 | ZNF92 | 0.713562 | 3 | 0 | 3 |
| SNX4 | PPP1R2 | 0.707212 | 4 | 0 | 3 |
| SNX4 | STAM2 | 0.70531 | 4 | 0 | 3 |
For details and further investigation, click here
