| Full name: HEAT repeat containing 5A | Alias Symbol: DKFZP434I1735 | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 25938 | HGNC ID: HGNC:20276 | Ensembl Gene: ENSG00000129493 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HEATR5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HEATR5A | 25938 | 226510_at | 0.3780 | 0.6802 | |
| GSE26886 | HEATR5A | 25938 | 226510_at | -0.6344 | 0.0901 | |
| GSE45670 | HEATR5A | 25938 | 226510_at | 0.0519 | 0.8115 | |
| GSE53622 | HEATR5A | 25938 | 7840 | -0.3381 | 0.0005 | |
| GSE53624 | HEATR5A | 25938 | 7245 | -0.5075 | 0.0000 | |
| GSE63941 | HEATR5A | 25938 | 226510_at | -0.8730 | 0.2387 | |
| GSE77861 | HEATR5A | 25938 | 226510_at | -0.4512 | 0.3391 | |
| GSE97050 | HEATR5A | 25938 | A_23_P433369 | -0.0195 | 0.9411 | |
| SRP007169 | HEATR5A | 25938 | RNAseq | 0.2034 | 0.5845 | |
| SRP008496 | HEATR5A | 25938 | RNAseq | 0.0074 | 0.9747 | |
| SRP064894 | HEATR5A | 25938 | RNAseq | -0.2070 | 0.3665 | |
| SRP133303 | HEATR5A | 25938 | RNAseq | 0.0157 | 0.9442 | |
| SRP159526 | HEATR5A | 25938 | RNAseq | -0.3371 | 0.3736 | |
| SRP193095 | HEATR5A | 25938 | RNAseq | -0.3065 | 0.0079 | |
| SRP219564 | HEATR5A | 25938 | RNAseq | -0.2433 | 0.3875 | |
| TCGA | HEATR5A | 25938 | RNAseq | -0.1118 | 0.1023 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HEATR5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HEATR5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HEATR5A | 25938 | 9 | 4 | 17 | |
| GSE20123 | HEATR5A | 25938 | 9 | 4 | 17 | |
| GSE43470 | HEATR5A | 25938 | 10 | 2 | 31 | |
| GSE46452 | HEATR5A | 25938 | 17 | 2 | 40 | |
| GSE47630 | HEATR5A | 25938 | 11 | 10 | 19 | |
| GSE54993 | HEATR5A | 25938 | 3 | 11 | 56 | |
| GSE54994 | HEATR5A | 25938 | 18 | 5 | 30 | |
| GSE60625 | HEATR5A | 25938 | 0 | 2 | 9 | |
| GSE74703 | HEATR5A | 25938 | 9 | 2 | 25 | |
| GSE74704 | HEATR5A | 25938 | 4 | 3 | 13 | |
| TCGA | HEATR5A | 25938 | 34 | 14 | 48 |
Total number of gains: 124; Total number of losses: 59; Total Number of normals: 305.
Somatic mutations of HEATR5A:
Generating mutation plots.
Highly correlated genes for HEATR5A:
Showing top 20/283 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HEATR5A | ARNT | 0.806475 | 3 | 0 | 3 |
| HEATR5A | TADA1 | 0.785523 | 3 | 0 | 3 |
| HEATR5A | CCNJ | 0.777465 | 3 | 0 | 3 |
| HEATR5A | RNF14 | 0.776958 | 3 | 0 | 3 |
| HEATR5A | NR2C2 | 0.769741 | 3 | 0 | 3 |
| HEATR5A | FBXO28 | 0.766253 | 3 | 0 | 3 |
| HEATR5A | CRBN | 0.765782 | 3 | 0 | 3 |
| HEATR5A | SNX4 | 0.758902 | 3 | 0 | 3 |
| HEATR5A | RTN3 | 0.75153 | 3 | 0 | 3 |
| HEATR5A | SRSF10 | 0.748657 | 3 | 0 | 3 |
| HEATR5A | ZNF227 | 0.748612 | 3 | 0 | 3 |
| HEATR5A | FASTKD2 | 0.748371 | 3 | 0 | 3 |
| HEATR5A | YY1 | 0.746365 | 3 | 0 | 3 |
| HEATR5A | EPC1 | 0.746116 | 3 | 0 | 3 |
| HEATR5A | CUL1 | 0.744443 | 3 | 0 | 3 |
| HEATR5A | SSBP1 | 0.737259 | 3 | 0 | 3 |
| HEATR5A | GLYR1 | 0.735243 | 3 | 0 | 3 |
| HEATR5A | PFKFB2 | 0.730413 | 4 | 0 | 4 |
| HEATR5A | YTHDF2 | 0.726827 | 4 | 0 | 4 |
| HEATR5A | EXOC5 | 0.724669 | 3 | 0 | 3 |
For details and further investigation, click here
