| Full name: acyl-CoA synthetase short chain family member 2 | Alias Symbol: ACS|ACSA|AceCS|dJ1161H23.1 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 55902 | HGNC ID: HGNC:15814 | Ensembl Gene: ENSG00000131069 | OMIM ID: 605832 |
| Drug and gene relationship at DGIdb | |||
Expression of ACSS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACSS2 | 55902 | 234312_s_at | 0.2270 | 0.5570 | |
| GSE26886 | ACSS2 | 55902 | 234312_s_at | -0.3781 | 0.0693 | |
| GSE45670 | ACSS2 | 55902 | 234312_s_at | 0.0175 | 0.9016 | |
| GSE53622 | ACSS2 | 55902 | 60101 | -0.4053 | 0.0001 | |
| GSE53624 | ACSS2 | 55902 | 60101 | -0.2261 | 0.0002 | |
| GSE63941 | ACSS2 | 55902 | 234312_s_at | 0.5054 | 0.2189 | |
| GSE77861 | ACSS2 | 55902 | 234312_s_at | -0.0062 | 0.9880 | |
| GSE97050 | ACSS2 | 55902 | A_23_P210900 | -0.0646 | 0.8826 | |
| SRP007169 | ACSS2 | 55902 | RNAseq | -0.5672 | 0.1037 | |
| SRP008496 | ACSS2 | 55902 | RNAseq | -0.8041 | 0.0002 | |
| SRP064894 | ACSS2 | 55902 | RNAseq | -0.0303 | 0.8541 | |
| SRP133303 | ACSS2 | 55902 | RNAseq | -0.1841 | 0.3516 | |
| SRP159526 | ACSS2 | 55902 | RNAseq | -0.0338 | 0.8856 | |
| SRP193095 | ACSS2 | 55902 | RNAseq | -0.6993 | 0.0054 | |
| SRP219564 | ACSS2 | 55902 | RNAseq | -0.1998 | 0.4170 | |
| TCGA | ACSS2 | 55902 | RNAseq | -0.3136 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACSS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACSS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACSS2 | 55902 | 16 | 0 | 14 | |
| GSE20123 | ACSS2 | 55902 | 16 | 0 | 14 | |
| GSE43470 | ACSS2 | 55902 | 12 | 0 | 31 | |
| GSE46452 | ACSS2 | 55902 | 29 | 0 | 30 | |
| GSE47630 | ACSS2 | 55902 | 24 | 1 | 15 | |
| GSE54993 | ACSS2 | 55902 | 0 | 18 | 52 | |
| GSE54994 | ACSS2 | 55902 | 25 | 1 | 27 | |
| GSE60625 | ACSS2 | 55902 | 0 | 0 | 11 | |
| GSE74703 | ACSS2 | 55902 | 11 | 0 | 25 | |
| GSE74704 | ACSS2 | 55902 | 11 | 0 | 9 | |
| TCGA | ACSS2 | 55902 | 50 | 3 | 43 |
Total number of gains: 194; Total number of losses: 23; Total Number of normals: 271.
Somatic mutations of ACSS2:
Generating mutation plots.
Highly correlated genes for ACSS2:
Showing top 20/156 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACSS2 | TMEM53 | 0.825038 | 3 | 0 | 3 |
| ACSS2 | RNFT2 | 0.784222 | 3 | 0 | 3 |
| ACSS2 | UQCR10 | 0.776279 | 3 | 0 | 3 |
| ACSS2 | COQ4 | 0.771072 | 3 | 0 | 3 |
| ACSS2 | PARG | 0.760756 | 3 | 0 | 3 |
| ACSS2 | LDLRAP1 | 0.749099 | 3 | 0 | 3 |
| ACSS2 | RFNG | 0.748612 | 3 | 0 | 3 |
| ACSS2 | HIC2 | 0.740279 | 3 | 0 | 3 |
| ACSS2 | SNX4 | 0.730036 | 3 | 0 | 3 |
| ACSS2 | RBM12 | 0.730004 | 3 | 0 | 3 |
| ACSS2 | ATP11B | 0.718315 | 4 | 0 | 4 |
| ACSS2 | NDUFB8 | 0.71173 | 3 | 0 | 3 |
| ACSS2 | SPEN | 0.709207 | 3 | 0 | 3 |
| ACSS2 | AFTPH | 0.707838 | 3 | 0 | 3 |
| ACSS2 | ELAVL1 | 0.707218 | 3 | 0 | 3 |
| ACSS2 | MAPRE1 | 0.7 | 3 | 0 | 3 |
| ACSS2 | LRP11 | 0.692426 | 3 | 0 | 3 |
| ACSS2 | AGFG1 | 0.689563 | 3 | 0 | 3 |
| ACSS2 | VAMP3 | 0.685742 | 4 | 0 | 3 |
| ACSS2 | MEAF6 | 0.682284 | 3 | 0 | 3 |
For details and further investigation, click here
