| Full name: transmembrane protein 41B | Alias Symbol: KIAA0033 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 440026 | HGNC ID: HGNC:28948 | Ensembl Gene: ENSG00000166471 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TMEM41B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM41B | 440026 | 212622_at | -0.2359 | 0.6496 | |
| GSE20347 | TMEM41B | 440026 | 212622_at | -0.3429 | 0.0062 | |
| GSE23400 | TMEM41B | 440026 | 212622_at | -0.1316 | 0.0907 | |
| GSE26886 | TMEM41B | 440026 | 212622_at | -0.8019 | 0.0000 | |
| GSE29001 | TMEM41B | 440026 | 212622_at | -0.2123 | 0.2757 | |
| GSE38129 | TMEM41B | 440026 | 212622_at | -0.1286 | 0.3729 | |
| GSE45670 | TMEM41B | 440026 | 212622_at | 0.0004 | 0.9984 | |
| GSE53622 | TMEM41B | 440026 | 65643 | -0.2159 | 0.0075 | |
| GSE53624 | TMEM41B | 440026 | 65643 | -0.1805 | 0.0352 | |
| GSE63941 | TMEM41B | 440026 | 212623_at | 0.1058 | 0.7984 | |
| GSE77861 | TMEM41B | 440026 | 212622_at | 0.0072 | 0.9875 | |
| GSE97050 | TMEM41B | A_21_P0000056 | 0.0825 | 0.8253 | ||
| SRP007169 | TMEM41B | 440026 | RNAseq | -0.5351 | 0.1923 | |
| SRP008496 | TMEM41B | 440026 | RNAseq | -0.5234 | 0.0339 | |
| SRP064894 | TMEM41B | 440026 | RNAseq | -0.2981 | 0.0424 | |
| SRP133303 | TMEM41B | 440026 | RNAseq | -0.0046 | 0.9799 | |
| SRP159526 | TMEM41B | 440026 | RNAseq | -0.3492 | 0.2703 | |
| SRP193095 | TMEM41B | 440026 | RNAseq | -0.3660 | 0.0007 | |
| SRP219564 | TMEM41B | 440026 | RNAseq | -0.1931 | 0.6876 | |
| TCGA | TMEM41B | 440026 | RNAseq | -0.0142 | 0.7931 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM41B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM41B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM41B | 440026 | 0 | 9 | 21 | |
| GSE20123 | TMEM41B | 440026 | 0 | 9 | 21 | |
| GSE43470 | TMEM41B | 440026 | 1 | 6 | 36 | |
| GSE46452 | TMEM41B | 440026 | 7 | 5 | 47 | |
| GSE47630 | TMEM41B | 440026 | 3 | 11 | 26 | |
| GSE54993 | TMEM41B | 440026 | 3 | 1 | 66 | |
| GSE54994 | TMEM41B | 440026 | 2 | 15 | 36 | |
| GSE60625 | TMEM41B | 440026 | 0 | 0 | 11 | |
| GSE74703 | TMEM41B | 440026 | 1 | 4 | 31 | |
| GSE74704 | TMEM41B | 440026 | 0 | 7 | 13 | |
| TCGA | TMEM41B | 440026 | 11 | 34 | 51 |
Total number of gains: 28; Total number of losses: 101; Total Number of normals: 359.
Somatic mutations of TMEM41B:
Generating mutation plots.
Highly correlated genes for TMEM41B:
Showing top 20/682 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM41B | CDC37L1 | 0.830628 | 3 | 0 | 3 |
| TMEM41B | TMEM17 | 0.793659 | 3 | 0 | 3 |
| TMEM41B | MIS18A | 0.773118 | 3 | 0 | 3 |
| TMEM41B | SRSF8 | 0.76834 | 3 | 0 | 3 |
| TMEM41B | CUL2 | 0.767742 | 3 | 0 | 3 |
| TMEM41B | EPM2AIP1 | 0.760889 | 3 | 0 | 3 |
| TMEM41B | ALDH1A3 | 0.74237 | 3 | 0 | 3 |
| TMEM41B | KIF21A | 0.741184 | 3 | 0 | 3 |
| TMEM41B | AKIP1 | 0.735507 | 3 | 0 | 3 |
| TMEM41B | SNX4 | 0.735028 | 3 | 0 | 3 |
| TMEM41B | ARHGEF3 | 0.732375 | 3 | 0 | 3 |
| TMEM41B | IK | 0.726138 | 3 | 0 | 3 |
| TMEM41B | GTF2A1 | 0.72582 | 3 | 0 | 3 |
| TMEM41B | AP3M1 | 0.724067 | 3 | 0 | 3 |
| TMEM41B | NAA25 | 0.723166 | 3 | 0 | 3 |
| TMEM41B | INO80 | 0.721437 | 3 | 0 | 3 |
| TMEM41B | TRAPPC6B | 0.721234 | 3 | 0 | 3 |
| TMEM41B | SUCLG2 | 0.716286 | 3 | 0 | 3 |
| TMEM41B | MTA3 | 0.713035 | 4 | 0 | 4 |
| TMEM41B | ANO8 | 0.71014 | 3 | 0 | 3 |
For details and further investigation, click here
