UTP15

 

Full name: UTP15 small subunit processome component Alias Symbol: FLJ12787|NET21|FLJ23637
Type: protein-coding gene Cytoband: 5q13.2
Entrez ID: 84135 HGNC ID: HGNC:25758 Ensembl Gene: ENSG00000164338 OMIM ID: 616194
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of UTP15:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UTP15 84135 228050_at 0.5107 0.4767
GSE26886 UTP15 84135 228050_at 0.1508 0.4875
GSE45670 UTP15 84135 228050_at 0.2702 0.1684
GSE53622 UTP15 84135 5662 -0.0885 0.3360
GSE53624 UTP15 84135 5662 0.1532 0.0308
GSE63941 UTP15 84135 228050_at 0.3663 0.5172
GSE77861 UTP15 84135 228050_at 0.0909 0.7017
GSE97050 UTP15 84135 A_23_P213441 0.3455 0.1694
SRP007169 UTP15 84135 RNAseq 0.4736 0.2222
SRP008496 UTP15 84135 RNAseq 0.7294 0.0268
SRP064894 UTP15 84135 RNAseq -0.0673 0.6667
SRP133303 UTP15 84135 RNAseq 0.2985 0.0725
SRP159526 UTP15 84135 RNAseq 0.2035 0.5536
SRP193095 UTP15 84135 RNAseq -0.1017 0.3514
SRP219564 UTP15 84135 RNAseq -0.1628 0.5623
TCGA UTP15 84135 RNAseq 0.0034 0.9572

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by UTP15 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of UTP15:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UTP15 84135 1 13 16
GSE20123 UTP15 84135 1 13 16
GSE43470 UTP15 84135 1 13 29
GSE46452 UTP15 84135 0 28 31
GSE47630 UTP15 84135 1 19 20
GSE54993 UTP15 84135 8 1 61
GSE54994 UTP15 84135 1 19 33
GSE60625 UTP15 84135 0 0 11
GSE74703 UTP15 84135 1 9 26
GSE74704 UTP15 84135 1 6 13
TCGA UTP15 84135 5 50 41

Total number of gains: 20; Total number of losses: 171; Total Number of normals: 297.  


 

Somatic mutations of UTP15:

 

Generating mutation plots.

 

Highly correlated genes for UTP15:

 

Showing top 20/250 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UTP15ARL100.729139303
UTP15C11orf240.71936303
UTP15SULF20.718483303
UTP15SMOX0.710821303
UTP15SNX50.709357303
UTP15NUP1070.708671303
UTP15MPP60.7031403
UTP15CCDC102B0.700972303
UTP15PLEK20.700314403
UTP15IARS20.69582303
UTP15POFUT10.694331303
UTP15PNP0.694181303
UTP15RAE10.689454303
UTP15CEBPB0.687755303
UTP15TDRD50.684836303
UTP15MED10.682661303
UTP15MYH100.680261303
UTP15MRPS50.679067303
UTP15PTPN10.678745303
UTP15UBE2E30.678325303

For details and further investigation, click here