| Full name: carboxyl ester lipase | Alias Symbol: BSSL|MODY8 | ||
| Type: protein-coding gene | Cytoband: 9q34.13 | ||
| Entrez ID: 1056 | HGNC ID: HGNC:1848 | Ensembl Gene: ENSG00000170835 | OMIM ID: 114840 |
| Drug and gene relationship at DGIdb | |||
Expression of CEL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEL | 1056 | 1553970_s_at | 1.1591 | 0.6165 | |
| GSE20347 | CEL | 1056 | 205910_s_at | 0.3843 | 0.5131 | |
| GSE23400 | CEL | 1056 | 205910_s_at | 0.1843 | 0.2893 | |
| GSE26886 | CEL | 1056 | 1553970_s_at | 1.4193 | 0.0379 | |
| GSE29001 | CEL | 1056 | 205910_s_at | -0.1006 | 0.9020 | |
| GSE38129 | CEL | 1056 | 205910_s_at | 0.9043 | 0.1201 | |
| GSE45670 | CEL | 1056 | 205910_s_at | 0.5691 | 0.2089 | |
| GSE53622 | CEL | 1056 | 71833 | -0.0124 | 0.9367 | |
| GSE53624 | CEL | 1056 | 71833 | -0.1286 | 0.2745 | |
| GSE63941 | CEL | 1056 | 1553970_s_at | 1.4706 | 0.2137 | |
| GSE77861 | CEL | 1056 | 1553970_s_at | -0.0175 | 0.9908 | |
| GSE97050 | CEL | 1056 | A_33_P3219303 | -0.0783 | 0.8432 | |
| SRP007169 | CEL | 1056 | RNAseq | 3.3568 | 0.0002 | |
| SRP133303 | CEL | 1056 | RNAseq | -0.5574 | 0.1022 | |
| SRP159526 | CEL | 1056 | RNAseq | 0.7734 | 0.1052 | |
| SRP193095 | CEL | 1056 | RNAseq | 0.7750 | 0.0481 | |
| SRP219564 | CEL | 1056 | RNAseq | 0.5338 | 0.5445 | |
| TCGA | CEL | 1056 | RNAseq | 0.9640 | 0.0082 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CEL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEL | 1056 | 5 | 7 | 18 | |
| GSE20123 | CEL | 1056 | 5 | 7 | 18 | |
| GSE43470 | CEL | 1056 | 4 | 7 | 32 | |
| GSE46452 | CEL | 1056 | 6 | 13 | 40 | |
| GSE47630 | CEL | 1056 | 4 | 15 | 21 | |
| GSE54993 | CEL | 1056 | 3 | 3 | 64 | |
| GSE54994 | CEL | 1056 | 12 | 9 | 32 | |
| GSE60625 | CEL | 1056 | 0 | 0 | 11 | |
| GSE74703 | CEL | 1056 | 4 | 5 | 27 | |
| GSE74704 | CEL | 1056 | 3 | 5 | 12 | |
| TCGA | CEL | 1056 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of CEL:
Generating mutation plots.
Highly correlated genes for CEL:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEL | SOHLH1 | 0.835834 | 3 | 0 | 3 |
| CEL | SCML4 | 0.665262 | 3 | 0 | 3 |
| CEL | IL22RA2 | 0.659272 | 3 | 0 | 3 |
| CEL | CAPS | 0.616192 | 3 | 0 | 3 |
| CEL | NOTCH1 | 0.615719 | 4 | 0 | 4 |
| CEL | MYLIP | 0.607763 | 5 | 0 | 4 |
| CEL | CFHR4 | 0.589557 | 5 | 0 | 3 |
| CEL | PRB3 | 0.588509 | 3 | 0 | 3 |
| CEL | TFDP2 | 0.584349 | 4 | 0 | 3 |
| CEL | MED23 | 0.573269 | 3 | 0 | 3 |
| CEL | BCL11A | 0.567877 | 3 | 0 | 3 |
| CEL | ANKRD36 | 0.565888 | 3 | 0 | 3 |
| CEL | GPR143 | 0.560005 | 4 | 0 | 3 |
| CEL | GSDMB | 0.555346 | 5 | 0 | 3 |
| CEL | PHF8 | 0.555284 | 6 | 0 | 5 |
| CEL | GDF15 | 0.540204 | 4 | 0 | 3 |
| CEL | DBP | 0.530856 | 4 | 0 | 3 |
| CEL | SEMA3F | 0.513383 | 7 | 0 | 3 |
| CEL | OLFM4 | 0.510804 | 4 | 0 | 3 |
| CEL | EFS | 0.50827 | 6 | 0 | 3 |
For details and further investigation, click here
