SPATA20

 

Full name: spermatogenesis associated 20 Alias Symbol: FLJ21347|SSP411|Tisp78
Type: protein-coding gene Cytoband: 17q21.33
Entrez ID: 64847 HGNC ID: HGNC:26125 Ensembl Gene: ENSG00000006282 OMIM ID: 613939
Drug and gene relationship at DGIdb

 

Expression of SPATA20:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SPATA20 64847 218164_at -0.0738 0.9170
GSE20347 SPATA20 64847 218164_at 0.3066 0.1077
GSE23400 SPATA20 64847 218164_at 0.4658 0.0000
GSE26886 SPATA20 64847 218164_at 0.8046 0.0130
GSE29001 SPATA20 64847 218164_at 0.2962 0.3248
GSE38129 SPATA20 64847 218164_at 0.2346 0.1465
GSE45670 SPATA20 64847 218164_at 0.1352 0.4771
GSE53622 SPATA20 64847 146850 0.5297 0.0000
GSE53624 SPATA20 64847 7737 0.5770 0.0000
GSE63941 SPATA20 64847 218164_at 0.1460 0.8159
GSE77861 SPATA20 64847 218164_at 0.6457 0.0263
GSE97050 SPATA20 64847 A_23_P118633 0.1964 0.3240
SRP007169 SPATA20 64847 RNAseq 0.0986 0.8770
SRP008496 SPATA20 64847 RNAseq 0.6238 0.1408
SRP064894 SPATA20 64847 RNAseq 0.9075 0.0000
SRP133303 SPATA20 64847 RNAseq 0.3625 0.0194
SRP159526 SPATA20 64847 RNAseq 0.7660 0.0015
SRP193095 SPATA20 64847 RNAseq 0.4645 0.0326
SRP219564 SPATA20 64847 RNAseq 0.4485 0.3157
TCGA SPATA20 64847 RNAseq -0.2226 0.0005

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by SPATA20 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SPATA20:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SPATA20 64847 5 2 23
GSE20123 SPATA20 64847 5 2 23
GSE43470 SPATA20 64847 3 2 38
GSE46452 SPATA20 64847 32 0 27
GSE47630 SPATA20 64847 9 0 31
GSE54993 SPATA20 64847 2 4 64
GSE54994 SPATA20 64847 9 6 38
GSE60625 SPATA20 64847 4 0 7
GSE74703 SPATA20 64847 3 2 31
GSE74704 SPATA20 64847 4 1 15
TCGA SPATA20 64847 26 8 62

Total number of gains: 102; Total number of losses: 27; Total Number of normals: 359.  


 

Somatic mutations of SPATA20:

 

Generating mutation plots.

 

Highly correlated genes for SPATA20:

 

Showing top 20/547 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SPATA20PHKA10.713534303
SPATA20PKIG0.661855404
SPATA20SLC35B20.65284303
SPATA20ZFP920.638234403
SPATA20SMARCD20.635219404
SPATA20WDR810.633744303
SPATA20PYCR20.629917303
SPATA20TUBA1B0.626867303
SPATA20FNDC10.624912303
SPATA20NCOR20.623872807
SPATA20NUP2100.620374303
SPATA20ZBED10.618399504
SPATA20BOLA30.616886303
SPATA20RAB340.613272303
SPATA20PFN10.612547403
SPATA20A2M0.612247303
SPATA20RAMP30.610492403
SPATA20SPTAN10.607304303
SPATA20HHAT0.60519303
SPATA20ZNF2750.603495605

For details and further investigation, click here