| Full name: fibronectin type III domain containing 1 | Alias Symbol: bA243O10.1|KIAA1866|dJ322A24.1 | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 84624 | HGNC ID: HGNC:21184 | Ensembl Gene: ENSG00000164694 | OMIM ID: 609991 |
| Drug and gene relationship at DGIdb | |||
Expression of FNDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FNDC1 | 84624 | 226930_at | 0.7290 | 0.5800 | |
| GSE26886 | FNDC1 | 84624 | 226930_at | 0.8273 | 0.0173 | |
| GSE45670 | FNDC1 | 84624 | 226930_at | 0.1422 | 0.8221 | |
| GSE53622 | FNDC1 | 84624 | 83673 | 3.4648 | 0.0000 | |
| GSE53624 | FNDC1 | 84624 | 77653 | 2.8944 | 0.0000 | |
| GSE63941 | FNDC1 | 84624 | 226930_at | -3.7050 | 0.0000 | |
| GSE77861 | FNDC1 | 84624 | 226930_at | 0.1019 | 0.6043 | |
| GSE97050 | FNDC1 | 84624 | A_33_P3290354 | 1.2887 | 0.0916 | |
| SRP007169 | FNDC1 | 84624 | RNAseq | 7.6226 | 0.0000 | |
| SRP008496 | FNDC1 | 84624 | RNAseq | 7.5449 | 0.0000 | |
| SRP064894 | FNDC1 | 84624 | RNAseq | 4.0662 | 0.0000 | |
| SRP133303 | FNDC1 | 84624 | RNAseq | 3.3599 | 0.0000 | |
| SRP159526 | FNDC1 | 84624 | RNAseq | 1.7061 | 0.0002 | |
| SRP219564 | FNDC1 | 84624 | RNAseq | 1.5090 | 0.1880 | |
| TCGA | FNDC1 | 84624 | RNAseq | 0.8126 | 0.0002 |
Upregulated datasets: 7; Downregulated datasets: 1.
Survival by FNDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FNDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FNDC1 | 84624 | 1 | 5 | 24 | |
| GSE20123 | FNDC1 | 84624 | 1 | 4 | 25 | |
| GSE43470 | FNDC1 | 84624 | 4 | 0 | 39 | |
| GSE46452 | FNDC1 | 84624 | 3 | 10 | 46 | |
| GSE47630 | FNDC1 | 84624 | 9 | 4 | 27 | |
| GSE54993 | FNDC1 | 84624 | 3 | 2 | 65 | |
| GSE54994 | FNDC1 | 84624 | 8 | 8 | 37 | |
| GSE60625 | FNDC1 | 84624 | 0 | 1 | 10 | |
| GSE74703 | FNDC1 | 84624 | 4 | 0 | 32 | |
| GSE74704 | FNDC1 | 84624 | 0 | 2 | 18 | |
| TCGA | FNDC1 | 84624 | 13 | 22 | 61 |
Total number of gains: 46; Total number of losses: 58; Total Number of normals: 384.
Somatic mutations of FNDC1:
Generating mutation plots.
Highly correlated genes for FNDC1:
Showing top 20/1008 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FNDC1 | CALU | 0.813925 | 7 | 0 | 7 |
| FNDC1 | COL8A1 | 0.81332 | 8 | 0 | 8 |
| FNDC1 | SULF1 | 0.811528 | 8 | 0 | 8 |
| FNDC1 | CTSK | 0.802011 | 9 | 0 | 9 |
| FNDC1 | VCAN | 0.797328 | 9 | 0 | 8 |
| FNDC1 | CDH11 | 0.796521 | 8 | 0 | 8 |
| FNDC1 | SPARC | 0.789455 | 9 | 0 | 8 |
| FNDC1 | COL6A3 | 0.779136 | 9 | 0 | 9 |
| FNDC1 | PCOLCE | 0.778058 | 9 | 0 | 9 |
| FNDC1 | LUM | 0.773489 | 8 | 0 | 8 |
| FNDC1 | RAB34 | 0.771118 | 3 | 0 | 3 |
| FNDC1 | POSTN | 0.769483 | 9 | 0 | 9 |
| FNDC1 | MMD | 0.769159 | 8 | 0 | 8 |
| FNDC1 | COL5A1 | 0.759649 | 9 | 0 | 9 |
| FNDC1 | THY1 | 0.751872 | 9 | 0 | 8 |
| FNDC1 | FAP | 0.750296 | 7 | 0 | 6 |
| FNDC1 | COL12A1 | 0.749973 | 9 | 0 | 9 |
| FNDC1 | COL3A1 | 0.747764 | 9 | 0 | 9 |
| FNDC1 | PYCR2 | 0.747758 | 3 | 0 | 3 |
| FNDC1 | AEBP1 | 0.745248 | 8 | 0 | 8 |
For details and further investigation, click here
