| Full name: phosphorylase kinase regulatory subunit alpha 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xq13.1 | ||
| Entrez ID: 5255 | HGNC ID: HGNC:8925 | Ensembl Gene: ENSG00000067177 | OMIM ID: 311870 |
| Drug and gene relationship at DGIdb | |||
PHKA1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04020 | Calcium signaling pathway | |
| hsa04910 | Insulin signaling pathway | |
| hsa04922 | Glucagon signaling pathway |
Expression of PHKA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHKA1 | 5255 | 205450_at | -0.0708 | 0.9264 | |
| GSE20347 | PHKA1 | 5255 | 205450_at | 0.0883 | 0.3965 | |
| GSE23400 | PHKA1 | 5255 | 205450_at | 0.0878 | 0.0610 | |
| GSE26886 | PHKA1 | 5255 | 205450_at | 0.0709 | 0.8198 | |
| GSE29001 | PHKA1 | 5255 | 205450_at | -0.0195 | 0.9311 | |
| GSE38129 | PHKA1 | 5255 | 205450_at | 0.1669 | 0.1061 | |
| GSE45670 | PHKA1 | 5255 | 205450_at | 0.2919 | 0.2220 | |
| GSE53622 | PHKA1 | 5255 | 30019 | -0.1149 | 0.2091 | |
| GSE53624 | PHKA1 | 5255 | 30019 | -0.1877 | 0.0244 | |
| GSE63941 | PHKA1 | 5255 | 205450_at | 0.6177 | 0.3644 | |
| GSE77861 | PHKA1 | 5255 | 205450_at | 0.2031 | 0.0899 | |
| GSE97050 | PHKA1 | 5255 | A_24_P238543 | -0.1902 | 0.3504 | |
| SRP007169 | PHKA1 | 5255 | RNAseq | -0.5861 | 0.2367 | |
| SRP008496 | PHKA1 | 5255 | RNAseq | -0.5765 | 0.0648 | |
| SRP064894 | PHKA1 | 5255 | RNAseq | -0.4950 | 0.0364 | |
| SRP133303 | PHKA1 | 5255 | RNAseq | 0.0500 | 0.7463 | |
| SRP159526 | PHKA1 | 5255 | RNAseq | -0.2795 | 0.2963 | |
| SRP193095 | PHKA1 | 5255 | RNAseq | -0.0710 | 0.5984 | |
| SRP219564 | PHKA1 | 5255 | RNAseq | 0.1939 | 0.6985 | |
| TCGA | PHKA1 | 5255 | RNAseq | -0.2551 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PHKA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHKA1:
No record found for this gene.
Somatic mutations of PHKA1:
Generating mutation plots.
Highly correlated genes for PHKA1:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHKA1 | ARV1 | 0.778698 | 3 | 0 | 3 |
| PHKA1 | INPP5E | 0.774907 | 3 | 0 | 3 |
| PHKA1 | C1orf115 | 0.744779 | 3 | 0 | 3 |
| PHKA1 | MTCP1 | 0.729617 | 3 | 0 | 3 |
| PHKA1 | SHANK3 | 0.720192 | 3 | 0 | 3 |
| PHKA1 | SPATA20 | 0.713534 | 3 | 0 | 3 |
| PHKA1 | NCBP1 | 0.708464 | 3 | 0 | 3 |
| PHKA1 | MRPL35 | 0.702091 | 3 | 0 | 3 |
| PHKA1 | CRLF3 | 0.694644 | 3 | 0 | 3 |
| PHKA1 | ST7L | 0.692321 | 3 | 0 | 3 |
| PHKA1 | USP45 | 0.690467 | 3 | 0 | 3 |
| PHKA1 | RAB12 | 0.689412 | 3 | 0 | 3 |
| PHKA1 | PTS | 0.688654 | 3 | 0 | 3 |
| PHKA1 | LANCL2 | 0.687301 | 3 | 0 | 3 |
| PHKA1 | ZC3HC1 | 0.684472 | 3 | 0 | 3 |
| PHKA1 | RTKN | 0.679121 | 3 | 0 | 3 |
| PHKA1 | PKN3 | 0.67365 | 3 | 0 | 3 |
| PHKA1 | EIF5A2 | 0.673569 | 3 | 0 | 3 |
| PHKA1 | EGFL7 | 0.667367 | 3 | 0 | 3 |
| PHKA1 | KPNA5 | 0.664805 | 3 | 0 | 3 |
For details and further investigation, click here
