| Full name: receptor activity modifying protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 10268 | HGNC ID: HGNC:9845 | Ensembl Gene: ENSG00000122679 | OMIM ID: 605155 |
| Drug and gene relationship at DGIdb | |||
RAMP3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04270 | Vascular smooth muscle contraction |
Expression of RAMP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAMP3 | 10268 | 205326_at | -0.0879 | 0.9204 | |
| GSE20347 | RAMP3 | 10268 | 205326_at | -0.1142 | 0.2602 | |
| GSE23400 | RAMP3 | 10268 | 205326_at | -0.0668 | 0.3700 | |
| GSE26886 | RAMP3 | 10268 | 205326_at | -0.0751 | 0.7370 | |
| GSE29001 | RAMP3 | 10268 | 205326_at | -0.2085 | 0.2441 | |
| GSE38129 | RAMP3 | 10268 | 205326_at | -0.3189 | 0.1369 | |
| GSE45670 | RAMP3 | 10268 | 205326_at | -0.4297 | 0.1374 | |
| GSE53622 | RAMP3 | 10268 | 112442 | -0.4804 | 0.0000 | |
| GSE53624 | RAMP3 | 10268 | 112442 | -0.2069 | 0.1030 | |
| GSE63941 | RAMP3 | 10268 | 205326_at | 0.1848 | 0.3248 | |
| GSE77861 | RAMP3 | 10268 | 205326_at | 0.2499 | 0.2309 | |
| GSE97050 | RAMP3 | 10268 | A_23_P111737 | 0.1125 | 0.6101 | |
| SRP007169 | RAMP3 | 10268 | RNAseq | -0.4365 | 0.4386 | |
| SRP064894 | RAMP3 | 10268 | RNAseq | 0.2974 | 0.4988 | |
| SRP133303 | RAMP3 | 10268 | RNAseq | -0.7555 | 0.0024 | |
| SRP159526 | RAMP3 | 10268 | RNAseq | -0.0012 | 0.9983 | |
| SRP193095 | RAMP3 | 10268 | RNAseq | 0.6485 | 0.0109 | |
| SRP219564 | RAMP3 | 10268 | RNAseq | 0.2402 | 0.6756 | |
| TCGA | RAMP3 | 10268 | RNAseq | -0.5486 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RAMP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAMP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAMP3 | 10268 | 13 | 0 | 17 | |
| GSE20123 | RAMP3 | 10268 | 12 | 0 | 18 | |
| GSE43470 | RAMP3 | 10268 | 4 | 0 | 39 | |
| GSE46452 | RAMP3 | 10268 | 11 | 1 | 47 | |
| GSE47630 | RAMP3 | 10268 | 8 | 1 | 31 | |
| GSE54993 | RAMP3 | 10268 | 0 | 8 | 62 | |
| GSE54994 | RAMP3 | 10268 | 16 | 3 | 34 | |
| GSE60625 | RAMP3 | 10268 | 0 | 0 | 11 | |
| GSE74703 | RAMP3 | 10268 | 4 | 0 | 32 | |
| GSE74704 | RAMP3 | 10268 | 6 | 0 | 14 | |
| TCGA | RAMP3 | 10268 | 50 | 7 | 39 |
Total number of gains: 124; Total number of losses: 20; Total Number of normals: 344.
Somatic mutations of RAMP3:
Generating mutation plots.
Highly correlated genes for RAMP3:
Showing top 20/335 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAMP3 | DLGAP2 | 0.713992 | 3 | 0 | 3 |
| RAMP3 | CDH5 | 0.687729 | 10 | 0 | 10 |
| RAMP3 | ECSCR | 0.68467 | 8 | 0 | 7 |
| RAMP3 | GJA4 | 0.679272 | 8 | 0 | 7 |
| RAMP3 | STRADA | 0.677415 | 3 | 0 | 3 |
| RAMP3 | ACKR1 | 0.67101 | 10 | 0 | 9 |
| RAMP3 | SELP | 0.667161 | 12 | 0 | 9 |
| RAMP3 | L3MBTL2 | 0.665507 | 3 | 0 | 3 |
| RAMP3 | TEK | 0.658531 | 9 | 0 | 7 |
| RAMP3 | PECAM1 | 0.6568 | 12 | 0 | 10 |
| RAMP3 | PTPRCAP | 0.656101 | 5 | 0 | 4 |
| RAMP3 | EPS8 | 0.651974 | 3 | 0 | 3 |
| RAMP3 | RCSD1 | 0.647618 | 4 | 0 | 3 |
| RAMP3 | MFNG | 0.638298 | 7 | 0 | 7 |
| RAMP3 | NRROS | 0.638159 | 6 | 0 | 5 |
| RAMP3 | DOK3 | 0.636029 | 6 | 0 | 5 |
| RAMP3 | STARD8 | 0.635588 | 9 | 0 | 7 |
| RAMP3 | APLNR | 0.630932 | 9 | 0 | 7 |
| RAMP3 | VWF | 0.630879 | 9 | 0 | 6 |
| RAMP3 | TSPAN18 | 0.630449 | 4 | 0 | 4 |
For details and further investigation, click here
