SERPINB9

 

Full name: serpin family B member 9 Alias Symbol: CAP3
Type: protein-coding gene Cytoband: 6p25.2
Entrez ID: 5272 HGNC ID: HGNC:8955 Ensembl Gene: ENSG00000170542 OMIM ID: 601799
Drug and gene relationship at DGIdb

 

Expression of SERPINB9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SERPINB9 5272 209723_at 0.1687 0.8772
GSE20347 SERPINB9 5272 209723_at -0.9418 0.0056
GSE23400 SERPINB9 5272 209723_at -0.5766 0.0000
GSE26886 SERPINB9 5272 209723_at -1.7921 0.0053
GSE29001 SERPINB9 5272 209723_at -0.8208 0.0255
GSE38129 SERPINB9 5272 209723_at -0.8007 0.0031
GSE45670 SERPINB9 5272 209723_at 0.0578 0.8588
GSE53622 SERPINB9 5272 76910 -0.3749 0.0133
GSE53624 SERPINB9 5272 76910 -0.4383 0.0014
GSE63941 SERPINB9 5272 209723_at -3.0610 0.0623
GSE77861 SERPINB9 5272 209723_at 0.4475 0.5720
GSE97050 SERPINB9 5272 A_24_P295010 0.2881 0.4681
SRP007169 SERPINB9 5272 RNAseq -0.3544 0.5629
SRP008496 SERPINB9 5272 RNAseq -0.4257 0.2928
SRP064894 SERPINB9 5272 RNAseq -0.4737 0.1061
SRP133303 SERPINB9 5272 RNAseq 0.2470 0.3378
SRP159526 SERPINB9 5272 RNAseq -0.9313 0.0782
SRP193095 SERPINB9 5272 RNAseq 0.4281 0.0191
SRP219564 SERPINB9 5272 RNAseq -0.3499 0.5004
TCGA SERPINB9 5272 RNAseq 0.3854 0.0010

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by SERPINB9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SERPINB9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SERPINB9 5272 4 5 21
GSE20123 SERPINB9 5272 4 5 21
GSE43470 SERPINB9 5272 8 4 31
GSE46452 SERPINB9 5272 1 10 48
GSE47630 SERPINB9 5272 7 8 25
GSE54993 SERPINB9 5272 1 1 68
GSE54994 SERPINB9 5272 10 3 40
GSE60625 SERPINB9 5272 0 1 10
GSE74703 SERPINB9 5272 7 3 26
GSE74704 SERPINB9 5272 2 2 16
TCGA SERPINB9 5272 17 30 49

Total number of gains: 61; Total number of losses: 72; Total Number of normals: 355.  


 

Somatic mutations of SERPINB9:

 

Generating mutation plots.

 

Highly correlated genes for SERPINB9:

 

Showing top 20/295 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SERPINB9ROBO10.772593303
SERPINB9HIF1A0.771792303
SERPINB9ATP6V1B20.754999303
SERPINB9RAB1A0.753236303
SERPINB9PDSS20.731492303
SERPINB9ZNF2170.730789303
SERPINB9DOK10.729905303
SERPINB9AKIRIN20.71848303
SERPINB9NUS10.716269303
SERPINB9ESR20.715972303
SERPINB9ASCC30.714527403
SERPINB9FAM155A0.706421303
SERPINB9SEC24D0.703671404
SERPINB9LAMP20.693507403
SERPINB9NDUFS10.692929303
SERPINB9ADCY70.691284605
SERPINB9TGFB10.683175303
SERPINB9HK20.680577303
SERPINB9XIAP0.680228403
SERPINB9ARSK0.677081303

For details and further investigation, click here