| Full name: SLIT-ROBO Rho GTPase activating protein 2C | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p11.2 | ||
| Entrez ID: 653464 | HGNC ID: HGNC:30584 | Ensembl Gene: ENSG00000171943 | OMIM ID: 614704 |
| Drug and gene relationship at DGIdb | |||
Expression of SRGAP2C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRGAP2C | 653464 | 228628_at | -0.3917 | 0.3495 | |
| GSE26886 | SRGAP2C | 653464 | 228628_at | -0.3723 | 0.2622 | |
| GSE45670 | SRGAP2C | 653464 | 228628_at | -0.5284 | 0.0133 | |
| GSE63941 | SRGAP2C | 653464 | 228628_at | -0.5804 | 0.4269 | |
| GSE77861 | SRGAP2C | 653464 | 228628_at | 0.3235 | 0.2994 | |
| SRP007169 | SRGAP2C | 653464 | RNAseq | 1.0002 | 0.1007 | |
| SRP008496 | SRGAP2C | 653464 | RNAseq | 0.8407 | 0.0470 | |
| SRP064894 | SRGAP2C | 653464 | RNAseq | 0.4188 | 0.0606 | |
| SRP133303 | SRGAP2C | 653464 | RNAseq | 0.1077 | 0.4933 | |
| SRP159526 | SRGAP2C | 653464 | RNAseq | -0.3396 | 0.3053 | |
| SRP193095 | SRGAP2C | 653464 | RNAseq | 0.0788 | 0.5591 | |
| SRP219564 | SRGAP2C | 653464 | RNAseq | 0.4641 | 0.1380 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of SRGAP2C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRGAP2C | 653464 | 11 | 0 | 19 | |
| GSE20123 | SRGAP2C | 653464 | 11 | 0 | 19 | |
| GSE43470 | SRGAP2C | 653464 | 7 | 0 | 36 | |
| GSE46452 | SRGAP2C | 653464 | 3 | 1 | 55 | |
| GSE47630 | SRGAP2C | 653464 | 14 | 0 | 26 | |
| GSE54993 | SRGAP2C | 653464 | 0 | 6 | 64 | |
| GSE54994 | SRGAP2C | 653464 | 14 | 0 | 39 | |
| GSE60625 | SRGAP2C | 653464 | 0 | 0 | 11 | |
| GSE74703 | SRGAP2C | 653464 | 7 | 0 | 29 | |
| GSE74704 | SRGAP2C | 653464 | 5 | 0 | 15 |
Total number of gains: 72; Total number of losses: 7; Total Number of normals: 313.
Somatic mutations of SRGAP2C:
Generating mutation plots.
Highly correlated genes for SRGAP2C:
Showing all 17 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRGAP2C | ZNF25 | 0.711388 | 3 | 0 | 3 |
| SRGAP2C | PIEZO2 | 0.668681 | 3 | 0 | 3 |
| SRGAP2C | PDGFRA | 0.643541 | 3 | 0 | 3 |
| SRGAP2C | SRGAP2 | 0.633394 | 3 | 0 | 3 |
| SRGAP2C | LXN | 0.606572 | 3 | 0 | 3 |
| SRGAP2C | GIMAP4 | 0.596858 | 3 | 0 | 3 |
| SRGAP2C | HSPA12B | 0.593925 | 3 | 0 | 3 |
| SRGAP2C | C1orf54 | 0.590338 | 4 | 0 | 3 |
| SRGAP2C | ZMYND11 | 0.57899 | 3 | 0 | 3 |
| SRGAP2C | SYNPO2 | 0.577227 | 3 | 0 | 3 |
| SRGAP2C | SLC16A4 | 0.566673 | 3 | 0 | 3 |
| SRGAP2C | KLHL15 | 0.557981 | 3 | 0 | 3 |
| SRGAP2C | FHL1 | 0.547514 | 4 | 0 | 3 |
| SRGAP2C | SCARB2 | 0.543605 | 3 | 0 | 3 |
| SRGAP2C | ADAMTS9-AS2 | 0.538312 | 3 | 0 | 3 |
| SRGAP2C | AGBL3 | 0.533751 | 3 | 0 | 3 |
| SRGAP2C | LARP7 | 0.532629 | 3 | 0 | 3 |
For details and further investigation, click here
