| Full name: piezo type mechanosensitive ion channel component 2 | Alias Symbol: FLJ23403|FLJ23144|HsT748|HsT771|FLJ34907 | ||
| Type: protein-coding gene | Cytoband: 18p11.22-p11.21 | ||
| Entrez ID: 63895 | HGNC ID: HGNC:26270 | Ensembl Gene: ENSG00000154864 | OMIM ID: 613629 |
| Drug and gene relationship at DGIdb | |||
Expression of PIEZO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIEZO2 | 63895 | 219602_s_at | -0.7137 | 0.2912 | |
| GSE20347 | PIEZO2 | 63895 | 219602_s_at | 0.1167 | 0.6555 | |
| GSE23400 | PIEZO2 | 63895 | 219602_s_at | -0.1094 | 0.0917 | |
| GSE26886 | PIEZO2 | 63895 | 1562488_at | -0.0073 | 0.9623 | |
| GSE29001 | PIEZO2 | 63895 | 219602_s_at | 0.4142 | 0.4332 | |
| GSE38129 | PIEZO2 | 63895 | 219602_s_at | 0.0751 | 0.7564 | |
| GSE45670 | PIEZO2 | 63895 | 219602_s_at | -1.7283 | 0.0000 | |
| GSE53622 | PIEZO2 | 63895 | 8535 | -0.3127 | 0.0020 | |
| GSE53624 | PIEZO2 | 63895 | 8535 | -0.3250 | 0.0000 | |
| GSE63941 | PIEZO2 | 63895 | 1562488_at | -0.4420 | 0.0157 | |
| GSE77861 | PIEZO2 | 63895 | 1562488_at | 0.0337 | 0.8183 | |
| GSE97050 | PIEZO2 | 63895 | A_33_P3351150 | 0.0140 | 0.9695 | |
| SRP007169 | PIEZO2 | 63895 | RNAseq | 1.4239 | 0.0517 | |
| SRP064894 | PIEZO2 | 63895 | RNAseq | -0.4910 | 0.1964 | |
| SRP133303 | PIEZO2 | 63895 | RNAseq | -1.1031 | 0.0000 | |
| SRP159526 | PIEZO2 | 63895 | RNAseq | 0.2884 | 0.7009 | |
| SRP193095 | PIEZO2 | 63895 | RNAseq | 0.1033 | 0.7878 | |
| SRP219564 | PIEZO2 | 63895 | RNAseq | -0.1369 | 0.8573 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PIEZO2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PIEZO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIEZO2 | 63895 | 6 | 3 | 21 | |
| GSE20123 | PIEZO2 | 63895 | 6 | 3 | 21 | |
| GSE43470 | PIEZO2 | 63895 | 1 | 6 | 36 | |
| GSE46452 | PIEZO2 | 63895 | 3 | 21 | 35 | |
| GSE47630 | PIEZO2 | 63895 | 7 | 17 | 16 | |
| GSE54993 | PIEZO2 | 63895 | 6 | 2 | 62 | |
| GSE54994 | PIEZO2 | 63895 | 8 | 8 | 37 | |
| GSE60625 | PIEZO2 | 63895 | 0 | 4 | 7 | |
| GSE74703 | PIEZO2 | 63895 | 1 | 4 | 31 | |
| GSE74704 | PIEZO2 | 63895 | 4 | 2 | 14 | |
| TCGA | PIEZO2 | 63895 | 28 | 24 | 44 |
Total number of gains: 70; Total number of losses: 94; Total Number of normals: 324.
Somatic mutations of PIEZO2:
Generating mutation plots.
Highly correlated genes for PIEZO2:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIEZO2 | SCARA5 | 0.759346 | 3 | 0 | 3 |
| PIEZO2 | CD300LG | 0.73673 | 3 | 0 | 3 |
| PIEZO2 | C16orf89 | 0.734389 | 4 | 0 | 3 |
| PIEZO2 | ZCCHC18 | 0.718518 | 4 | 0 | 3 |
| PIEZO2 | KCTD19 | 0.698769 | 3 | 0 | 3 |
| PIEZO2 | RNF180 | 0.69729 | 3 | 0 | 3 |
| PIEZO2 | SCN3A | 0.687673 | 5 | 0 | 4 |
| PIEZO2 | VIPR2 | 0.679878 | 3 | 0 | 3 |
| PIEZO2 | ANKDD1A | 0.678014 | 5 | 0 | 5 |
| PIEZO2 | SRGAP2C | 0.668681 | 3 | 0 | 3 |
| PIEZO2 | GPR146 | 0.660494 | 3 | 0 | 3 |
| PIEZO2 | ASRGL1 | 0.643964 | 5 | 0 | 4 |
| PIEZO2 | SETDB2 | 0.64251 | 4 | 0 | 3 |
| PIEZO2 | GPR88 | 0.641751 | 4 | 0 | 3 |
| PIEZO2 | KANK3 | 0.636634 | 4 | 0 | 3 |
| PIEZO2 | GNAL | 0.629981 | 4 | 0 | 3 |
| PIEZO2 | SNED1 | 0.627291 | 7 | 0 | 6 |
| PIEZO2 | DMGDH | 0.626392 | 4 | 0 | 3 |
| PIEZO2 | ZBTB20 | 0.625039 | 5 | 0 | 3 |
| PIEZO2 | FGD5 | 0.61393 | 5 | 0 | 4 |
For details and further investigation, click here
