| Full name: four and a half LIM domains 1 | Alias Symbol: SLIM1|KYO-T|bA535K18.1|FHL1B|XMPMA|FLH1A|MGC111107 | ||
| Type: protein-coding gene | Cytoband: Xq26.3 | ||
| Entrez ID: 2273 | HGNC ID: HGNC:3702 | Ensembl Gene: ENSG00000022267 | OMIM ID: 300163 |
| Drug and gene relationship at DGIdb | |||
FHL1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway |
Expression of FHL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FHL1 | 2273 | 201540_at | -1.9672 | 0.1328 | |
| GSE20347 | FHL1 | 2273 | 201540_at | -1.1262 | 0.0203 | |
| GSE23400 | FHL1 | 2273 | 201540_at | -1.2838 | 0.0000 | |
| GSE26886 | FHL1 | 2273 | 201540_at | 1.4922 | 0.0285 | |
| GSE29001 | FHL1 | 2273 | 201540_at | -0.7748 | 0.1742 | |
| GSE38129 | FHL1 | 2273 | 201540_at | -1.7632 | 0.0006 | |
| GSE45670 | FHL1 | 2273 | 201540_at | -3.3652 | 0.0000 | |
| GSE53622 | FHL1 | 2273 | 11989 | -2.7399 | 0.0000 | |
| GSE53624 | FHL1 | 2273 | 11989 | -2.2378 | 0.0000 | |
| GSE63941 | FHL1 | 2273 | 201540_at | -4.2395 | 0.0167 | |
| GSE77861 | FHL1 | 2273 | 201540_at | 1.7732 | 0.0076 | |
| GSE97050 | FHL1 | 2273 | A_33_P3849275 | -1.9771 | 0.0828 | |
| SRP007169 | FHL1 | 2273 | RNAseq | 1.9594 | 0.0010 | |
| SRP008496 | FHL1 | 2273 | RNAseq | 2.2388 | 0.0000 | |
| SRP064894 | FHL1 | 2273 | RNAseq | -1.4668 | 0.0004 | |
| SRP133303 | FHL1 | 2273 | RNAseq | -1.3301 | 0.1003 | |
| SRP159526 | FHL1 | 2273 | RNAseq | -2.0225 | 0.0000 | |
| SRP193095 | FHL1 | 2273 | RNAseq | 0.0276 | 0.9518 | |
| SRP219564 | FHL1 | 2273 | RNAseq | -1.1225 | 0.3100 | |
| TCGA | FHL1 | 2273 | RNAseq | -0.8673 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 9.
Survival by FHL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FHL1:
No record found for this gene.
Somatic mutations of FHL1:
Generating mutation plots.
Highly correlated genes for FHL1:
Showing top 20/979 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FHL1 | SORCS1 | 0.847156 | 4 | 0 | 4 |
| FHL1 | CYP21A2 | 0.845759 | 3 | 0 | 3 |
| FHL1 | CLEC3B | 0.835651 | 3 | 0 | 3 |
| FHL1 | PREX2 | 0.811643 | 4 | 0 | 4 |
| FHL1 | MYADM | 0.79641 | 4 | 0 | 4 |
| FHL1 | LMOD1 | 0.79288 | 12 | 0 | 12 |
| FHL1 | SYNM | 0.790286 | 12 | 0 | 12 |
| FHL1 | CHRDL1 | 0.787517 | 10 | 0 | 9 |
| FHL1 | AOC3 | 0.786457 | 12 | 0 | 11 |
| FHL1 | PPP1R12B | 0.783385 | 11 | 0 | 10 |
| FHL1 | MSRB3 | 0.782118 | 7 | 0 | 7 |
| FHL1 | PDLIM3 | 0.78128 | 13 | 0 | 13 |
| FHL1 | ARHGEF9 | 0.780016 | 7 | 0 | 7 |
| FHL1 | ITGA9 | 0.779562 | 7 | 0 | 6 |
| FHL1 | ACTG2 | 0.777598 | 13 | 0 | 13 |
| FHL1 | ANGPTL1 | 0.777529 | 7 | 0 | 6 |
| FHL1 | CNN1 | 0.777278 | 11 | 0 | 11 |
| FHL1 | MRVI1 | 0.775146 | 7 | 0 | 6 |
| FHL1 | MYH11 | 0.774678 | 12 | 0 | 12 |
| FHL1 | ZNF347 | 0.774618 | 3 | 0 | 3 |
For details and further investigation, click here
