| Full name: serine racemase | Alias Symbol: ILV1|ISO1 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 63826 | HGNC ID: HGNC:14398 | Ensembl Gene: ENSG00000167720 | OMIM ID: 606477 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SRR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRR | 63826 | 219205_at | -0.6767 | 0.0631 | |
| GSE20347 | SRR | 63826 | 219205_at | -0.4955 | 0.0006 | |
| GSE23400 | SRR | 63826 | 219205_at | -0.1202 | 0.0033 | |
| GSE26886 | SRR | 63826 | 219205_at | -0.0958 | 0.6455 | |
| GSE29001 | SRR | 63826 | 219205_at | -0.4221 | 0.1026 | |
| GSE38129 | SRR | 63826 | 219205_at | -0.6808 | 0.0000 | |
| GSE45670 | SRR | 63826 | 219205_at | -0.5613 | 0.0008 | |
| GSE53622 | SRR | 63826 | 47313 | -0.1530 | 0.0386 | |
| GSE53624 | SRR | 63826 | 47313 | 0.2597 | 0.0001 | |
| GSE63941 | SRR | 63826 | 219205_at | -1.1589 | 0.0883 | |
| GSE77861 | SRR | 63826 | 219205_at | -0.4834 | 0.0028 | |
| GSE97050 | SRR | 63826 | A_23_P141248 | -0.3563 | 0.2038 | |
| SRP007169 | SRR | 63826 | RNAseq | -0.5388 | 0.2417 | |
| SRP008496 | SRR | 63826 | RNAseq | -0.4348 | 0.2064 | |
| SRP064894 | SRR | 63826 | RNAseq | 0.2250 | 0.2874 | |
| SRP133303 | SRR | 63826 | RNAseq | -0.3588 | 0.0310 | |
| SRP159526 | SRR | 63826 | RNAseq | -0.4428 | 0.1841 | |
| SRP193095 | SRR | 63826 | RNAseq | -0.3030 | 0.0214 | |
| SRP219564 | SRR | 63826 | RNAseq | -0.0983 | 0.8153 | |
| TCGA | SRR | 63826 | RNAseq | -0.1667 | 0.0317 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SRR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SRR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRR | 63826 | 4 | 2 | 24 | |
| GSE20123 | SRR | 63826 | 4 | 3 | 23 | |
| GSE43470 | SRR | 63826 | 1 | 6 | 36 | |
| GSE46452 | SRR | 63826 | 34 | 1 | 24 | |
| GSE47630 | SRR | 63826 | 7 | 1 | 32 | |
| GSE54993 | SRR | 63826 | 4 | 3 | 63 | |
| GSE54994 | SRR | 63826 | 6 | 9 | 38 | |
| GSE60625 | SRR | 63826 | 4 | 0 | 7 | |
| GSE74703 | SRR | 63826 | 1 | 3 | 32 | |
| GSE74704 | SRR | 63826 | 2 | 1 | 17 | |
| TCGA | SRR | 63826 | 17 | 22 | 57 |
Total number of gains: 84; Total number of losses: 51; Total Number of normals: 353.
Somatic mutations of SRR:
Generating mutation plots.
Highly correlated genes for SRR:
Showing top 20/829 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRR | KLHL29 | 0.807335 | 3 | 0 | 3 |
| SRR | DCTN6 | 0.772895 | 3 | 0 | 3 |
| SRR | ANGPTL1 | 0.756634 | 3 | 0 | 3 |
| SRR | VPS36 | 0.754791 | 3 | 0 | 3 |
| SRR | ITPRIP | 0.752176 | 3 | 0 | 3 |
| SRR | OAT | 0.745971 | 4 | 0 | 4 |
| SRR | SYTL4 | 0.738163 | 3 | 0 | 3 |
| SRR | DNAJB9 | 0.729725 | 3 | 0 | 3 |
| SRR | LONRF2 | 0.72774 | 3 | 0 | 3 |
| SRR | FIGN | 0.724724 | 3 | 0 | 3 |
| SRR | KCTD6 | 0.723066 | 4 | 0 | 3 |
| SRR | PODN | 0.720834 | 3 | 0 | 3 |
| SRR | RASGEF1B | 0.719963 | 3 | 0 | 3 |
| SRR | PPM1L | 0.715464 | 3 | 0 | 3 |
| SRR | SLC9A9 | 0.71539 | 3 | 0 | 3 |
| SRR | MTIF3 | 0.713487 | 4 | 0 | 3 |
| SRR | KIAA1191 | 0.712698 | 4 | 0 | 3 |
| SRR | PHYHD1 | 0.711679 | 4 | 0 | 4 |
| SRR | PREX2 | 0.711333 | 4 | 0 | 3 |
| SRR | ZNF547 | 0.706908 | 3 | 0 | 3 |
For details and further investigation, click here
