| Full name: serine/arginine repetitive matrix 4 | Alias Symbol: nSR100 | ||
| Type: protein-coding gene | Cytoband: 12q24.23 | ||
| Entrez ID: 84530 | HGNC ID: HGNC:29389 | Ensembl Gene: ENSG00000139767 | OMIM ID: 613103 |
| Drug and gene relationship at DGIdb | |||
Expression of SRRM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRRM4 | 84530 | 236151_at | -0.0573 | 0.8512 | |
| GSE26886 | SRRM4 | 84530 | 236151_at | -0.3400 | 0.0153 | |
| GSE45670 | SRRM4 | 84530 | 236151_at | 0.0127 | 0.9012 | |
| GSE63941 | SRRM4 | 84530 | 236151_at | 0.1087 | 0.4221 | |
| GSE77861 | SRRM4 | 84530 | 236151_at | -0.1377 | 0.1562 | |
| SRP133303 | SRRM4 | 84530 | RNAseq | -0.3019 | 0.1388 | |
| TCGA | SRRM4 | 84530 | RNAseq | -3.5599 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SRRM4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SRRM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRRM4 | 84530 | 6 | 2 | 22 | |
| GSE20123 | SRRM4 | 84530 | 6 | 2 | 22 | |
| GSE43470 | SRRM4 | 84530 | 2 | 2 | 39 | |
| GSE46452 | SRRM4 | 84530 | 9 | 1 | 49 | |
| GSE47630 | SRRM4 | 84530 | 9 | 3 | 28 | |
| GSE54993 | SRRM4 | 84530 | 0 | 5 | 65 | |
| GSE54994 | SRRM4 | 84530 | 6 | 6 | 41 | |
| GSE60625 | SRRM4 | 84530 | 0 | 0 | 11 | |
| GSE74703 | SRRM4 | 84530 | 2 | 1 | 33 | |
| GSE74704 | SRRM4 | 84530 | 3 | 2 | 15 | |
| TCGA | SRRM4 | 84530 | 21 | 11 | 64 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of SRRM4:
Generating mutation plots.
Highly correlated genes for SRRM4:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRRM4 | IFNA4 | 0.767702 | 3 | 0 | 3 |
| SRRM4 | OR51I1 | 0.674061 | 3 | 0 | 3 |
| SRRM4 | PPM1E | 0.6555 | 3 | 0 | 3 |
| SRRM4 | ASMTL-AS1 | 0.651019 | 3 | 0 | 3 |
| SRRM4 | TTR | 0.647705 | 3 | 0 | 3 |
| SRRM4 | CHRNA2 | 0.64447 | 3 | 0 | 3 |
| SRRM4 | CASC11 | 0.639838 | 3 | 0 | 3 |
| SRRM4 | LINC00421 | 0.639105 | 3 | 0 | 3 |
| SRRM4 | KRTAP5-8 | 0.638039 | 4 | 0 | 4 |
| SRRM4 | HPYR1 | 0.637759 | 3 | 0 | 3 |
| SRRM4 | SV2C | 0.625881 | 3 | 0 | 3 |
| SRRM4 | NME9 | 0.623238 | 3 | 0 | 3 |
| SRRM4 | EPHA5-AS1 | 0.622709 | 3 | 0 | 3 |
| SRRM4 | TTTY11 | 0.614891 | 4 | 0 | 3 |
| SRRM4 | PCAT4 | 0.61253 | 4 | 0 | 4 |
| SRRM4 | LINC00838 | 0.609101 | 3 | 0 | 3 |
| SRRM4 | C8B | 0.597482 | 3 | 0 | 3 |
| SRRM4 | FGF10-AS1 | 0.597462 | 4 | 0 | 3 |
| SRRM4 | ANO2 | 0.596878 | 3 | 0 | 3 |
| SRRM4 | CDRT1 | 0.574943 | 3 | 0 | 3 |
For details and further investigation, click here
