| Full name: myogenic factor 5 | Alias Symbol: bHLHc2 | ||
| Type: protein-coding gene | Cytoband: 12q21.31 | ||
| Entrez ID: 4617 | HGNC ID: HGNC:7565 | Ensembl Gene: ENSG00000111049 | OMIM ID: 159990 |
| Drug and gene relationship at DGIdb | |||
Expression of MYF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYF5 | 4617 | 207424_at | 0.0638 | 0.8170 | |
| GSE20347 | MYF5 | 4617 | 207424_at | -0.0421 | 0.4904 | |
| GSE23400 | MYF5 | 4617 | 207424_at | -0.0854 | 0.0004 | |
| GSE26886 | MYF5 | 4617 | 207424_at | 0.1112 | 0.3878 | |
| GSE29001 | MYF5 | 4617 | 207424_at | -0.1214 | 0.3752 | |
| GSE38129 | MYF5 | 4617 | 207424_at | -0.0484 | 0.3392 | |
| GSE45670 | MYF5 | 4617 | 207424_at | 0.0295 | 0.7558 | |
| GSE63941 | MYF5 | 4617 | 207424_at | 0.0525 | 0.6937 | |
| GSE77861 | MYF5 | 4617 | 207424_at | -0.0105 | 0.9332 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYF5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MYF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYF5 | 4617 | 3 | 4 | 23 | |
| GSE20123 | MYF5 | 4617 | 3 | 4 | 23 | |
| GSE43470 | MYF5 | 4617 | 3 | 1 | 39 | |
| GSE46452 | MYF5 | 4617 | 9 | 1 | 49 | |
| GSE47630 | MYF5 | 4617 | 10 | 1 | 29 | |
| GSE54993 | MYF5 | 4617 | 0 | 5 | 65 | |
| GSE54994 | MYF5 | 4617 | 7 | 1 | 45 | |
| GSE60625 | MYF5 | 4617 | 0 | 0 | 11 | |
| GSE74703 | MYF5 | 4617 | 3 | 1 | 32 | |
| GSE74704 | MYF5 | 4617 | 2 | 3 | 15 | |
| TCGA | MYF5 | 4617 | 15 | 13 | 68 |
Total number of gains: 55; Total number of losses: 34; Total Number of normals: 399.
Somatic mutations of MYF5:
Generating mutation plots.
Highly correlated genes for MYF5:
Showing top 20/274 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYF5 | CCR4 | 0.699282 | 3 | 0 | 3 |
| MYF5 | DOC2B | 0.695024 | 3 | 0 | 3 |
| MYF5 | CCIN | 0.682255 | 3 | 0 | 3 |
| MYF5 | TREML2 | 0.681761 | 3 | 0 | 3 |
| MYF5 | PWWP2A | 0.676263 | 3 | 0 | 3 |
| MYF5 | LRTM1 | 0.673362 | 4 | 0 | 3 |
| MYF5 | ARMC4 | 0.666323 | 3 | 0 | 3 |
| MYF5 | SHOX | 0.661708 | 3 | 0 | 3 |
| MYF5 | KSR1 | 0.655754 | 3 | 0 | 3 |
| MYF5 | ST8SIA5 | 0.655015 | 4 | 0 | 3 |
| MYF5 | SHBG | 0.652765 | 3 | 0 | 3 |
| MYF5 | OR2J2 | 0.649053 | 3 | 0 | 3 |
| MYF5 | USP29 | 0.647858 | 3 | 0 | 3 |
| MYF5 | SRPK3 | 0.647274 | 3 | 0 | 3 |
| MYF5 | ADRA2B | 0.645485 | 3 | 0 | 3 |
| MYF5 | GPD1 | 0.645393 | 4 | 0 | 4 |
| MYF5 | IFNA14 | 0.64528 | 3 | 0 | 3 |
| MYF5 | TNP1 | 0.64507 | 3 | 0 | 3 |
| MYF5 | ACHE | 0.644634 | 3 | 0 | 3 |
| MYF5 | IL5RA | 0.643215 | 3 | 0 | 3 |
For details and further investigation, click here
