| Full name: stromal interaction molecule 1 | Alias Symbol: GOK|D11S4896E | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 6786 | HGNC ID: HGNC:11386 | Ensembl Gene: ENSG00000167323 | OMIM ID: 605921 |
STIM1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04020 | Calcium signaling pathway | |
| hsa04611 | Platelet activation |
Expression of STIM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STIM1 | 6786 | 202764_at | -0.6189 | 0.1934 | |
| GSE20347 | STIM1 | 6786 | 202764_at | -0.8237 | 0.0000 | |
| GSE23400 | STIM1 | 6786 | 202764_at | -0.4347 | 0.0000 | |
| GSE26886 | STIM1 | 6786 | 202764_at | -0.4859 | 0.0005 | |
| GSE29001 | STIM1 | 6786 | 202764_at | -0.6294 | 0.0044 | |
| GSE38129 | STIM1 | 6786 | 202764_at | -0.7563 | 0.0000 | |
| GSE45670 | STIM1 | 6786 | 202764_at | -0.2800 | 0.0384 | |
| GSE53622 | STIM1 | 6786 | 18690 | -0.9953 | 0.0000 | |
| GSE53624 | STIM1 | 6786 | 137016 | -1.0375 | 0.0000 | |
| GSE63941 | STIM1 | 6786 | 202764_at | -0.3326 | 0.2405 | |
| GSE77861 | STIM1 | 6786 | 202764_at | -0.2727 | 0.2231 | |
| GSE97050 | STIM1 | 6786 | A_23_P53162 | -0.6641 | 0.0962 | |
| SRP007169 | STIM1 | 6786 | RNAseq | -1.3270 | 0.0001 | |
| SRP008496 | STIM1 | 6786 | RNAseq | -1.3581 | 0.0000 | |
| SRP064894 | STIM1 | 6786 | RNAseq | -0.9426 | 0.0000 | |
| SRP133303 | STIM1 | 6786 | RNAseq | -1.0765 | 0.0000 | |
| SRP159526 | STIM1 | 6786 | RNAseq | -1.1246 | 0.0046 | |
| SRP193095 | STIM1 | 6786 | RNAseq | -0.6153 | 0.0001 | |
| SRP219564 | STIM1 | 6786 | RNAseq | -0.8459 | 0.0003 | |
| TCGA | STIM1 | 6786 | RNAseq | -0.1292 | 0.0207 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by STIM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STIM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STIM1 | 6786 | 1 | 12 | 17 | |
| GSE20123 | STIM1 | 6786 | 1 | 11 | 18 | |
| GSE43470 | STIM1 | 6786 | 1 | 8 | 34 | |
| GSE46452 | STIM1 | 6786 | 7 | 8 | 44 | |
| GSE47630 | STIM1 | 6786 | 4 | 13 | 23 | |
| GSE54993 | STIM1 | 6786 | 3 | 1 | 66 | |
| GSE54994 | STIM1 | 6786 | 1 | 12 | 40 | |
| GSE60625 | STIM1 | 6786 | 0 | 0 | 11 | |
| GSE74703 | STIM1 | 6786 | 1 | 7 | 28 | |
| GSE74704 | STIM1 | 6786 | 0 | 8 | 12 | |
| TCGA | STIM1 | 6786 | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 119; Total Number of normals: 342.
Somatic mutations of STIM1:
Generating mutation plots.
Highly correlated genes for STIM1:
Showing top 20/1399 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STIM1 | TCP11L2 | 0.764915 | 5 | 0 | 5 |
| STIM1 | SMIM5 | 0.764351 | 5 | 0 | 5 |
| STIM1 | EVPL | 0.753029 | 10 | 0 | 10 |
| STIM1 | NLRX1 | 0.752407 | 10 | 0 | 10 |
| STIM1 | MGLL | 0.739071 | 11 | 0 | 10 |
| STIM1 | SPAG17 | 0.737865 | 3 | 0 | 3 |
| STIM1 | TMPRSS11B | 0.732724 | 5 | 0 | 5 |
| STIM1 | MAPK3 | 0.731726 | 10 | 0 | 10 |
| STIM1 | MUC15 | 0.728086 | 5 | 0 | 5 |
| STIM1 | BTBD11 | 0.727518 | 6 | 0 | 6 |
| STIM1 | VSIG10L | 0.727143 | 6 | 0 | 6 |
| STIM1 | CYSRT1 | 0.726101 | 6 | 0 | 6 |
| STIM1 | CCNYL1 | 0.724428 | 5 | 0 | 5 |
| STIM1 | RASSF3 | 0.721597 | 3 | 0 | 3 |
| STIM1 | LRP10 | 0.72002 | 12 | 0 | 11 |
| STIM1 | ABLIM1 | 0.719271 | 11 | 0 | 10 |
| STIM1 | MAB21L3 | 0.717921 | 5 | 0 | 5 |
| STIM1 | FAM214A | 0.71713 | 5 | 0 | 5 |
| STIM1 | RNH1 | 0.715653 | 12 | 0 | 11 |
| STIM1 | FCHO2 | 0.71493 | 7 | 0 | 6 |
For details and further investigation, click here
